PDB: 376 resultsInfo pagesStatus searchChemie searchBIRD

---

5KJX	Co-crystal Structure of PKA RI alpha CNB-B domain with cAMP Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, cAMP-dependent protein kinase type I-alpha regulatory subunit Authors: Lorenz, R, Moon, E, Kim, J.J, Huang, G.Y, Kim, C, Herberg, F.W. Deposit date: 2016-06-20 Release date: 2017-06-28 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Mutations of PKA cyclic nucleotide-binding domains reveal novel aspects of cyclic nucleotide selectivity. Biochem. J., 474, 2017
1Q3E	HCN2J 443-645 in the presence of cGMP Descriptor: CYCLIC GUANOSINE MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 Authors: Zagotta, W.N, Olivier, N.B, Black, K.D, Young, E.C, Olson, R, Gouaux, J.E. Deposit date: 2003-07-29 Release date: 2003-09-09 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural basis for modulation and agonist specificity of HCN pacemaker channels Nature, 425, 2003
1I5Z	STRUCTURE OF CRP-CAMP AT 1.9 A Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, CATABOLITE GENE ACTIVATOR PROTEIN Authors: White, M.A, Lee, J.C, Fox, R.O. Deposit date: 2001-03-01 Release date: 2003-06-17 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (1.9 Å) Cite: The effect of the D53H point mutation on the macroscopic motions of E. coli Cyclic AMP Receptor Protein To be Published
3MDP	Crystal structure of a Putative Cyclic nucleotide-binding protein (Gmet_1532) from Geobacter metallireducens GS-15 at 1.90 A resolution Descriptor: 1,2-ETHANEDIOL, Cyclic nucleotide-binding domain (CNMP-BD) protein, SUCCINIC ACID Authors: Joint Center for Structural Genomics (JCSG) Deposit date: 2010-03-30 Release date: 2010-05-19 Last modified: 2023-02-01 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal structure of a Putative Cyclic nucleotide-binding protein (Gmet_1532) from Geobacter metallireducens GS-15 at 1.90 A resolution To be published
3B02	Crystal structure of TTHB099, a transcriptional regulator CRP family from Thermus thermophilus HB8 Descriptor: Transcriptional regulator, Crp family Authors: Agari, Y, Kuramitsu, S, Shinkai, A, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2011-06-03 Release date: 2011-06-15 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.92 Å) Cite: X-ray crystal structure of TTHB099, a CRP/FNR superfamily transcriptional regulator from Thermus thermophilus HB8, reveals a DNA-binding protein with no required allosteric effector molecule Proteins, 80, 2012
2PTM	Structure and rearrangements in the carboxy-terminal region of SpIH channels Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, COBALT HEXAMMINE(III), Hyperpolarization-activated (Ih) channel Authors: Flynn, G.E, Black, K.D, Islas, L.D, Sankaran, B, Zagotta, W.N. Deposit date: 2007-05-08 Release date: 2007-06-19 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.93 Å) Cite: Structure and rearrangements in the carboxy-terminal region of SpIH channels. Structure, 15, 2007
5BV6	PKG II's Carboxyl Terminal Cyclic Nucleotide Binding Domain (CNB-B) in a complex with cGMP Descriptor: ACETATE ION, CALCIUM ION, GUANOSINE-3',5'-MONOPHOSPHATE, ... Authors: Campbell, J.C, Reger, A.S, Huang, G.Y, Sankaran, B, Kim, J.J, Kim, C.W. Deposit date: 2015-06-04 Release date: 2016-01-20 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.94 Å) Cite: Structural Basis of Cyclic Nucleotide Selectivity in cGMP-dependent Protein Kinase II. J.Biol.Chem., 291, 2016
3QOP	Domain-domain flexibility leads to allostery within the camp receptor protein (CRP) Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Catabolite gene activator, GLYCEROL Authors: Knapp, J, White, M.A, Lee, J.C. Deposit date: 2011-02-10 Release date: 2012-04-04 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.96 Å) Cite: Domain-Domain Flexibility Leads to Allostery within the Camp Receptor Protein (Crp) To be Published
4FT8	E. coli Catabolite Activator Protein with Cobalt and Sulfate Ligands Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, COBALT (II) ION, Catabolite gene activator, ... Authors: Rao, R, Lawson, C.L. Deposit date: 2012-06-27 Release date: 2013-12-18 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.966 Å) Cite: Structure of catabolite activator protein with cobalt(II) and sulfate. Acta Crystallogr F Struct Biol Commun, 70, 2014
7T4U	Crystal Structure of cGMP-dependent Protein Kinase Descriptor: 3-amino-4-({(2S,3S)-3-[(1S)-1-(3,5-dichlorophenyl)-2-hydroxyethoxy]-2-phenylpiperidin-1-yl}methyl)benzoic acid, cGMP-dependent protein kinase 1 Authors: Zebisch, M, Silvestre, L, Fischmann, T.O. Deposit date: 2021-12-10 Release date: 2023-06-14 Last modified: 2023-07-12 Method: X-RAY DIFFRACTION (1.99 Å) Cite: Selective small molecule activation of PKG1alpha: structure and function Commun Biol, 2023
4KU8	Structures of PKGI Reveal a cGMP-Selective Activation Mechanism Descriptor: GLYCINE, cGMP-dependent Protein Kinase 1 Authors: Huang, G.Y, Kim, J.J, Reger, A.S, Lorenz, R, Moon, E.W, Casteel, D.E, Sankaran, B, Herberg, F.W, Kim, C. Deposit date: 2013-05-21 Release date: 2014-01-15 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.994 Å) Cite: Structural Basis for Cyclic-Nucleotide Selectivity and cGMP-Selective Activation of PKG I. Structure, 22, 2014
4LLO	Structure of the eag domain-CNBHD complex of the mouse EAG1 channel Descriptor: Potassium voltage-gated channel subfamily H member 1 Authors: Haitin, Y, Carlson, A.E, Zagotta, W.N. Deposit date: 2013-07-09 Release date: 2013-08-28 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.995 Å) Cite: The structural mechanism of KCNH-channel regulation by the eag domain. Nature, 501, 2013
3E5X	OCPA complexed CprK Descriptor: (3-CHLORO-4-HYDROXYPHENYL)ACETIC ACID, Cyclic nucleotide-binding protein Authors: Levy, C. Deposit date: 2008-08-14 Release date: 2008-12-09 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.999 Å) Cite: Molecular basis of halorespiration control by CprK, a CRP-FNR type transcriptional regulator Mol.Microbiol., 70, 2008
3E6D	Crystal Structure of CprK C200S Descriptor: Cyclic nucleotide-binding protein Authors: Levy, C. Deposit date: 2008-08-15 Release date: 2008-09-30 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2 Å) Cite: Molecular basis of halorespiration control by CprK, a CRP-FNR type transcriptional regulator Mol.Microbiol., 70, 2008
5KBF	cAMP bound PfPKA-R (141-441) Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, CAMP-dependent protein kinase regulatory subunit, putative Authors: Littler, D.R, Gilson, P.R, Crabb, B.S, Rossjohn, J.J. Deposit date: 2016-06-03 Release date: 2016-10-12 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2 Å) Cite: Disrupting the Allosteric Interaction between the Plasmodium falciparum cAMP-dependent Kinase and Its Regulatory Subunit. J. Biol. Chem., 291, 2016
4OFG	Co-crystal structure of carboxy cGMP binding domain of Plasmodium falciparum PKG with cGMP Descriptor: CGMP-dependent protein kinase, CYCLIC GUANOSINE MONOPHOSPHATE, ETHANOL, ... Authors: Kim, J.J, Sanabria figueroa, E, Kim, C. Deposit date: 2014-01-14 Release date: 2015-01-21 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal Structures of the Carboxyl cGMP Binding Domain of the Plasmodium falciparum cGMP-dependent Protein Kinase Reveal a Novel Capping Triad Crucial for Merozoite Egress. Plos Pathog., 11, 2015
3FHI	Crystal structure of a complex between the catalytic and regulatory (RI{alpha}) subunits of PKA Descriptor: MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, cAMP-dependent protein kinase catalytic subunit alpha, ... Authors: Kim, C. Deposit date: 2008-12-09 Release date: 2009-04-14 Last modified: 2021-10-20 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structure of a complex between the catalytic and regulatory (RIalpha) subunits of PKA. Science, 307, 2005
5KJY	Co-crystal structure of PKA RI alpha CNB-B mutant (G316R/A336T) with cAMP Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, cAMP-dependent protein kinase type I-alpha regulatory subunit Authors: Lorenz, R, Moon, E, Kim, J.J, Huang, G.Y, Kim, C, Herberg, F.W. Deposit date: 2016-06-20 Release date: 2017-06-28 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2 Å) Cite: Mutations of PKA cyclic nucleotide-binding domains reveal novel aspects of cyclic nucleotide selectivity. Biochem. J., 474, 2017
3D0S	cAMP receptor protein from m.tuberculosis, cAMP-free form Descriptor: CHLORIDE ION, TRANSCRIPTIONAL REGULATORY PROTEIN Authors: Gallagher, D.T, Robinson, H, Reddy, P.T. Deposit date: 2008-05-02 Release date: 2009-02-03 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structure of cAMP receptor protein from M. tuberculosis in the unliganded form To be Published
4ORF	cAMP-binding acyltransferase from Mycobacterium smegmatis, mutant R95K Descriptor: Acetyltransferase Pat, CHLORIDE ION Authors: Podobnik, M, Rebolj, K, Visweswariah, S.S. Deposit date: 2014-02-11 Release date: 2014-04-30 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2 Å) Cite: Allostery and Conformational Dynamics in cAMP-binding Acyltransferases. J.Biol.Chem., 289, 2014
5D1I	Structure of Cyclic nucleotide-binding-like protein from Brucella abortus bv. 1 str. 9-941 Descriptor: Cyclic nucleotide-binding protein Authors: He, Z, Dong, J, Li, X, Gao, Y. Deposit date: 2015-08-04 Release date: 2015-09-09 Last modified: 2016-01-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structure of cyclic nucleotide-binding-like protein from Brucella abortus Biochem.Biophys.Res.Commun., 468, 2015
6BQ8	Joint X-ray/neutron structure of PKG II CNB-B domain in complex with 8-pCPT-cGMP Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(~2~H_2_)amino-8-[(4-chlorophenyl)sulfanyl]-9-[(2S,4aR,6R,7R,7aS)-2-hydroxy-7-(~2~H)hydroxy-2-oxotetrahydro-2H,4H-2lambda~5~-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl](~2~H)-1,9-dihydro-6H-purin-6-one, STRONTIUM ION, ... Authors: Kim, C, Kovalevsky, A, Gerlits, O. Deposit date: 2017-11-27 Release date: 2018-03-21 Last modified: 2024-04-03 Method: NEUTRON DIFFRACTION (2 Å), X-RAY DIFFRACTION Cite: Neutron Crystallography Detects Differences in Protein Dynamics: Structure of the PKG II Cyclic Nucleotide Binding Domain in Complex with an Activator. Biochemistry, 57, 2018
3CLP	M. loti cyclic-nucleotide binding domain mutant 2 Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Mll3241 protein Authors: Clayton, G.M, Altieri, S.L, Thomas, L.R, Morais-Cabral, J.H. Deposit date: 2008-03-19 Release date: 2008-08-05 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural and Energetic Analysis of Activation by a Cyclic Nucleotide Binding Domain. J.Mol.Biol., 381, 2008
2PQQ	Structural Genomics, the crystal structure of the N-terminal domain of a transcriptional regulator from Streptomyces coelicolor A3(2) Descriptor: FORMIC ACID, Putative transcriptional regulator Authors: Tan, K, Xu, X, Zheng, H, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) Deposit date: 2007-05-02 Release date: 2007-06-05 Last modified: 2017-10-18 Method: X-RAY DIFFRACTION (2 Å) Cite: The crystal structure of the N-terminal domain of a transcriptional regulator from Streptomyces coelicolor A3(2) To be Published
1Q43	HCN2I 443-640 in the presence of cAMP, selenomethionine derivative Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 Authors: Zagotta, W.N, Olivier, N.B, Black, K.D, Young, E.C, Olson, R, Gouaux, J.E. Deposit date: 2003-08-01 Release date: 2003-09-09 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural basis for modulation and agonist specificity of HCN pacemaker channels Nature, 425, 2003

<12345678910111213141516>