4OFG

Co-crystal structure of carboxy cGMP binding domain of Plasmodium falciparum PKG with cGMP

Summary for 4OFG

• Entry DOI: 10.2210/pdb4ofg/pdb
• Related: 4OFF
• Descriptor: CGMP-dependent protein kinase, CYCLIC GUANOSINE MONOPHOSPHATE, PENTANE-1,5-DIAMINE, ... (6 entities in total)
• Functional Keywords: phosphate binding cassette/cyclic gmp binding domain/pkg, serine/threonine kinase, tf2i, irag, cgmp binding, transferase
• Biological source: Plasmodium falciparum
• Total number of polymer chains: 1
• Total formula weight: 18799.78

Authors

Kim, J.J.,Sanabria figueroa, E.,Kim, C. (deposition date: 2014-01-14, release date: 2015-01-21, Last modification date: 2024-02-28)

• Primary citation: Kim, J.J.,Flueck, C.,Franz, E.,Sanabria-Figueroa, E.,Thompson, E.,Lorenz, R.,Bertinetti, D.,Baker, D.A.,Herberg, F.W.,Kim, C.; Crystal Structures of the Carboxyl cGMP Binding Domain of the Plasmodium falciparum cGMP-dependent Protein Kinase Reveal a Novel Capping Triad Crucial for Merozoite Egress.; Plos Pathog., 11:e1004639-e1004639, 2015; PubMed: 25646845; DOI: 10.1371/journal.ppat.1004639

Experimental method

X-RAY DIFFRACTION (2 Å)