4OFG
Co-crystal structure of carboxy cGMP binding domain of Plasmodium falciparum PKG with cGMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | CGMP-dependent protein kinase | polymer | 144 | 16954.4 | 1 | UniProt (Q8MMZ4) Pfam (PF00027) UniProt (by SIFTS) (Q8I719) | Plasmodium falciparum | |
| 2 | B (A) | CYCLIC GUANOSINE MONOPHOSPHATE | non-polymer | 345.2 | 1 | Chemie (PCG) PubChem (177270406) PubChem (136759845) PubChem (135398570) PubChem (135402012) PubChem (135415582) PubChem (135530416) PubChem (135566687) PubChem (135612771) PubChem (136122637) PubChem (136183234) PubChem (136183235) PubChem (136239427) PubChem (136268916) PubChem (136454903) PubChem (136454906) PubChem (136488083) PubChem (136488088) PubChem (136499047) PubChem (136678837) PubChem (137218937) PubChem (137234705) PubChem (137279777) PubChem (138399475) PubChem (164162904) | |||
| 3 | C, D, E, F, G... (A) | PENTANE-1,5-DIAMINE | non-polymer | 102.2 | 6 | Chemie (N2P) PubChem (273) | |||
| 4 | I, J, K (A) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 5 | L, M, N, O, P... (A) | ETHANOL | non-polymer | 46.1 | 13 | Chemie (EOH) | |||
| 6 | Y (A) | water | water | 18.0 | 50 | Chemie (HOH) |
Sequence modifications
A: 401 - 542 (UniProt: Q8MMZ4)
| PDB | External Database | Details |
|---|---|---|
| Gly 399 | - | expression tag |
| Ser 400 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 16954.4 | |
| Non-Polymers* | Number of molecules | 23 |
| Total formula weight | 1845.3 | |
| All* | Total formula weight | 18799.8 |
