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6NOG
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BU of 6nog by Molmil
Poised-state Dot1L bound to the H2B-Ubiquitinated nucleosome
Descriptor: 601 DNA Strand 1, 601 DNA Strand 2, Histone H2A type 1, ...
Authors:Worden, E.J, Hoffmann, N.A, Wolberger, C.
Deposit date:2019-01-16
Release date:2019-02-20
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Mechanism of Cross-talk between H2B Ubiquitination and H3 Methylation by Dot1L.
Cell, 176, 2019
6NN6
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BU of 6nn6 by Molmil
Structure of Dot1L-H2BK120ub nucleosome complex
Descriptor: DNA (145-MER), Histone H2A type 1, Histone H2B 1.1, ...
Authors:Anderson, C.J, Baird, M.R, Hsu, A, Barbour, E.H, Koyama, Y, Borgnia, M.J, McGinty, R.K.
Deposit date:2019-01-14
Release date:2019-02-13
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural Basis for Recognition of Ubiquitylated Nucleosome by Dot1L Methyltransferase.
Cell Rep, 26, 2019
6J62
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BU of 6j62 by Molmil
Crystal structure of mISG15/NS1B complex
Descriptor: Non-structural protein 1, Ubiquitin-like protein ISG15
Authors:Jiang, Y.N, Wang, X.Q.
Deposit date:2019-01-12
Release date:2019-12-25
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.486 Å)
Cite:Crystal structure of mISG15/NS1B complex
To Be Published
6QF8
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BU of 6qf8 by Molmil
Solution NMR ensemble for human ubiquitin at 298K compiled using the CoMAND method
Descriptor: Polyubiquitin-B
Authors:ElGamacy, M, Truffault, V, Zhu, H, Coles, M.
Deposit date:2019-01-09
Release date:2019-04-10
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Mapping Local Conformational Landscapes of Proteins in Solution.
Structure, 27, 2019
6NJD
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BU of 6njd by Molmil
Crystal structure of RavD (residues 1-200) from Legionella pneumophila (strain Corby) complexed with Met-1 linked di-ubiquitin
Descriptor: Di-ubiquitin, MAGNESIUM ION, RavD
Authors:Wang, X, Zhou, Y, Zhu, Y.
Deposit date:2019-01-03
Release date:2019-05-22
Last modified:2020-01-08
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:A bacterial effector deubiquitinase specifically hydrolyses linear ubiquitin chains to inhibit host inflammatory signalling.
Nat Microbiol, 4, 2019
6NJG
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BU of 6njg by Molmil
Ubiquitin Variant in Complex with Ubiquitin Interacting Motif
Descriptor: Polyubiquitin-B, Vacuolar protein sorting-associated protein 27
Authors:Manczyk, N, Sicheri, F.
Deposit date:2019-01-03
Release date:2019-03-06
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Dimerization of a ubiquitin variant leads to high affinity interactions with a ubiquitin interacting motif.
Protein Sci., 28, 2019
6NJ9
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BU of 6nj9 by Molmil
Active state Dot1L bound to the H2B-Ubiquitinated nucleosome, 2-to-1 complex
Descriptor: 601 DNA Strand 1, 601 DNA Strand 2, Histone H2A type 1, ...
Authors:Worden, E.J, Hoffmann, N.A, Wolberger, C.
Deposit date:2019-01-02
Release date:2019-02-20
Last modified:2021-06-16
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:Mechanism of Cross-talk between H2B Ubiquitination and H3 Methylation by Dot1L.
Cell, 176, 2019
6N8O
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BU of 6n8o by Molmil
Cryo-EM structure of Rpl10-inserted (RI) pre-60S ribosomal subunit
Descriptor: 5.8S rRNA, 5S rRNA, 60S ribosomal export protein NMD3, ...
Authors:Zhou, Y, Musalgaonkar, S, Johnson, A.W, Taylor, D.W.
Deposit date:2018-11-29
Release date:2019-03-13
Last modified:2020-01-08
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome.
Nat Commun, 10, 2019
6N8N
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BU of 6n8n by Molmil
Cryo-EM structure of Lsg1-engaged (LE) pre-60S ribosomal subunit
Descriptor: 5.8S rRNA, 5S rRNA, 60S ribosomal export protein NMD3, ...
Authors:Zhou, Y, Musalgaonkar, S, Johnson, A.W, Taylor, D.W.
Deposit date:2018-11-29
Release date:2019-03-13
Last modified:2020-01-08
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome.
Nat Commun, 10, 2019
6N8M
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BU of 6n8m by Molmil
Cryo-EM structure of pre-Lsg1 (PL) pre-60S ribosomal subunit
Descriptor: 5.8S RNA, 5S rRNA, 60S ribosomal export protein NMD3, ...
Authors:Zhou, Y, Musalgaonkar, S, Johnson, A.W, Taylor, D.W.
Deposit date:2018-11-29
Release date:2019-03-13
Last modified:2020-01-08
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome.
Nat Commun, 10, 2019
6N6R
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BU of 6n6r by Molmil
Crystal structure of ABIN-1 UBAN in complex with two M1-linked di-ubiquitins
Descriptor: TNFAIP3-interacting protein 1, Ubiquitin
Authors:Rahighi, S, Dikic, I, Wakatsuki, S.
Deposit date:2018-11-27
Release date:2019-07-17
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Molecular Recognition of M1-Linked Ubiquitin Chains by Native and Phosphorylated UBAN Domains.
J.Mol.Biol., 431, 2019
6N5M
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BU of 6n5m by Molmil
Crystal structure of ABIN-1 UBAN in complex with one M1-linked di-ubiquitin
Descriptor: Polyubiquitin-C, TNFAIP3-interacting protein 1
Authors:Rahighi, S, Dikic, I, Wakatsuki, S.
Deposit date:2018-11-22
Release date:2019-07-17
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Molecular Recognition of M1-Linked Ubiquitin Chains by Native and Phosphorylated UBAN Domains.
J.Mol.Biol., 431, 2019
6ISU
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BU of 6isu by Molmil
Crystal structure of Lys27-linked di-ubiquitin in complex with its selective interacting protein UCHL3
Descriptor: Ubiquitin, Ubiquitin carboxyl-terminal hydrolase isozyme L3
Authors:Ding, S, Pan, M, Zheng, Q, Ren, Y, Hong, D.
Deposit date:2018-11-19
Release date:2019-02-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.866 Å)
Cite:Chemical Protein Synthesis Enabled Mechanistic Studies on the Molecular Recognition of K27-linked Ubiquitin Chains.
Angew. Chem. Int. Ed. Engl., 58, 2019
6I7Q
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BU of 6i7q by Molmil
Structure of pVHL-elongin B-elongin C (VCB) in complex with hydroxylated-HIF-2alpha (523-542) in the C2221 form
Descriptor: Elongin-B, Elongin-C, Endothelial PAS domain-containing protein 1, ...
Authors:Chowdhury, R, Aguilera, L.S, Schofield, C.J.
Deposit date:2018-11-17
Release date:2019-11-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.798 Å)
Cite:HIF-2alpha-pVHL-elongin B-elongin C complex
To Be Published
6I7R
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BU of 6i7r by Molmil
Structure of pVHL-elongin B-elongin C (VCB) in complex with hydroxylated-HIF-2alpha (523-542) in the P43212 form
Descriptor: Elongin-B, Elongin-C, Endothelial PAS domain-containing protein 1, ...
Authors:Chowdhury, R, Aguilera, L.S, Schofield, C.J.
Deposit date:2018-11-17
Release date:2019-11-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.949 Å)
Cite:HIF-2alpha-pVHL-elongin B-elongin C complex
To Be Published
6I5N
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BU of 6i5n by Molmil
Crystal structure of SOCS2:Elongin C:Elongin B in complex with growth hormone receptor peptide
Descriptor: COBALT (II) ION, Elongin-B, Elongin-C, ...
Authors:Kung, W.W, Ramachandran, S, Makukhin, N, Bruno, E, Ciulli, A.
Deposit date:2018-11-14
Release date:2019-05-29
Last modified:2019-06-19
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structural insights into substrate recognition by the SOCS2 E3 ubiquitin ligase.
Nat Commun, 10, 2019
6I5J
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BU of 6i5j by Molmil
Crystal structure of SOCS2:Elongin C:Elongin B in complex with growth hormone receptor peptide
Descriptor: COBALT (II) ION, Elongin-B, Elongin-C, ...
Authors:Kung, W.W, Ramachandran, S, Makukhin, N, Bruno, E, Ciulli, A.
Deposit date:2018-11-13
Release date:2019-05-29
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural insights into substrate recognition by the SOCS2 E3 ubiquitin ligase.
Nat Commun, 10, 2019
6I4X
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BU of 6i4x by Molmil
Crystal structure of SOCS2:Elongin C:Elongin B in complex with erythropoietin receptor peptide
Descriptor: DI(HYDROXYETHYL)ETHER, Elongin-B, Elongin-C, ...
Authors:Kung, W.W, Ramachandran, S, Makukhin, N, Bruno, E, Ciulli, A.
Deposit date:2018-11-12
Release date:2019-05-29
Last modified:2019-06-19
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Structural insights into substrate recognition by the SOCS2 E3 ubiquitin ligase.
Nat Commun, 10, 2019
6N13
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BU of 6n13 by Molmil
UbcH7-Ub Complex with R0RBR Parkin and phosphoubiquitin
Descriptor: E3 ubiquitin-protein ligase parkin, Ubiquitin-conjugating enzyme E2 L3, ZINC ION, ...
Authors:Condos, T.E.C, Dunkerley, K.M, Freeman, E.A, Barber, K.R, Aguirre, J.D, Chaugule, V.K, Xiao, Y, Konermann, L, Walden, H, Shaw, G.S.
Deposit date:2018-11-08
Release date:2018-11-28
Last modified:2020-01-08
Method:SOLUTION NMR
Cite:Synergistic recruitment of UbcH7~Ub and phosphorylated Ubl domain triggers parkin activation.
EMBO J., 37, 2018
6IP6
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BU of 6ip6 by Molmil
Cryo-EM structure of the CMV-stalled human 80S ribosome with HCV IRES (Structure iii)
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Yokoyama, T, Shigematsu, H, Shirouzu, M, Imataka, H, Ito, T.
Deposit date:2018-11-02
Release date:2019-05-29
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:HCV IRES Captures an Actively Translating 80S Ribosome.
Mol.Cell, 74, 2019
6IP8
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BU of 6ip8 by Molmil
Cryo-EM structure of the HCV IRES dependently initiated CMV-stalled 80S ribosome (Structure iv)
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Yokoyama, T, Shigematsu, H, Shirouzu, M, Imataka, H, Ito, T.
Deposit date:2018-11-02
Release date:2019-05-29
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:HCV IRES Captures an Actively Translating 80S Ribosome.
Mol.Cell, 74, 2019
6IP5
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BU of 6ip5 by Molmil
Cryo-EM structure of the CMV-stalled human 80S ribosome (Structure ii)
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Yokoyama, T, Shigematsu, H, Shirouzu, M, Imataka, H, Ito, T.
Deposit date:2018-11-02
Release date:2019-05-29
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:HCV IRES Captures an Actively Translating 80S Ribosome.
Mol.Cell, 74, 2019
6MUN
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BU of 6mun by Molmil
Structure of hRpn10 bound to UBQLN2 UBL
Descriptor: 26S proteasome non-ATPase regulatory subunit 4, Ubiquilin-2
Authors:Chen, X, Walters, K.J.
Deposit date:2018-10-23
Release date:2019-09-04
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structure of hRpn10 Bound to UBQLN2 UBL Illustrates Basis for Complementarity between Shuttle Factors and Substrates at the Proteasome.
J.Mol.Biol., 431, 2019
6MTB
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BU of 6mtb by Molmil
Rabbit 80S ribosome with P- and Z-site tRNAs (unrotated state)
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
Authors:Brown, A, Baird, M.R, Yip, M.C.J, Murray, J, Shao, S.
Deposit date:2018-10-19
Release date:2018-11-21
Last modified:2019-05-15
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structures of translationally inactive mammalian ribosomes.
Elife, 7, 2018
6MTD
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BU of 6mtd by Molmil
Rabbit 80S ribosome with eEF2 and SERBP1 (unrotated state with 40S head swivel)
Descriptor: 18S rRNA, 28S rRNA, 5.8S rRNA, ...
Authors:Brown, A, Baird, M.R, Yip, M.C.J, Murray, J, Shao, S.
Deposit date:2018-10-19
Release date:2018-11-21
Last modified:2019-05-15
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structures of translationally inactive mammalian ribosomes.
Elife, 7, 2018

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