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6I7Q

Structure of pVHL-elongin B-elongin C (VCB) in complex with hydroxylated-HIF-2alpha (523-542) in the C2221 form

Summary for 6I7Q
Entry DOI10.2210/pdb6i7q/pdb
DescriptorElongin-B, Elongin-C, Endothelial PAS domain-containing protein 1, ... (6 entities in total)
Functional Keywordse3 ubiquitin ligase, gene regulation, von hippel lindau, prolyl hydroxylation, hif, tumor suppressor, cancer, proteosomal degradation, ubiquitin
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains4
Total formula weight45076.06
Authors
Chowdhury, R.,Aguilera, L.S.,Schofield, C.J. (deposition date: 2018-11-17, release date: 2019-11-27, Last modification date: 2024-01-24)
Primary citationChowdhury, R.,Schofield, C.J.
HIF-2alpha-pVHL-elongin B-elongin C complex
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.798 Å)
Structure validation

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