6ISU

Crystal structure of Lys27-linked di-ubiquitin in complex with its selective interacting protein UCHL3

Summary for 6ISU

Entry DOI	10.2210/pdb6isu/pdb
Descriptor	Ubiquitin carboxyl-terminal hydrolase isozyme L3, Ubiquitin, ... (4 entities in total)
Functional Keywords	ubiquitination, uchl3, lys27-linked di-ubiquitin, hydrolase
Biological source	Homo sapiens (Human) More
Total number of polymer chains	3
Total formula weight	43384.27
Authors	Ding, S.,Pan, M.,Zheng, Q.,Ren, Y.,Hong, D. (deposition date: 2018-11-19, release date: 2019-02-06, Last modification date: 2023-11-22)
Primary citation	Pan, M.,Zheng, Q.,Ding, S.,Zhang, L.,Qu, Q.,Wang, T.,Hong, D.,Ren, Y.,Liang, L.,Chen, C.,Mei, Z.,Liu, L. Chemical Protein Synthesis Enabled Mechanistic Studies on the Molecular Recognition of K27-linked Ubiquitin Chains. Angew. Chem. Int. Ed. Engl., 58:2627-2631, 2019 Cited by PubMed: 30589182 DOI: 10.1002/anie.201810814 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.866 Å)

Structure validation