6I5N

Crystal structure of SOCS2:Elongin C:Elongin B in complex with growth hormone receptor peptide

Summary for 6I5N

• Entry DOI: 10.2210/pdb6i5n/pdb
• Descriptor: Suppressor of cytokine signaling 2, Elongin-B, Elongin-C, ... (7 entities in total)
• Functional Keywords: complex, signaling protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 10
• Total formula weight: 89973.48

Authors

Kung, W.W.,Ramachandran, S.,Makukhin, N.,Bruno, E.,Ciulli, A. (deposition date: 2018-11-14, release date: 2019-05-29, Last modification date: 2019-06-19)

• Primary citation: Kung, W.W.,Ramachandran, S.,Makukhin, N.,Bruno, E.,Ciulli, A.; Structural insights into substrate recognition by the SOCS2 E3 ubiquitin ligase.; Nat Commun, 10:2534-2534, 2019; PubMed: 31182716; DOI: 10.1038/s41467-019-10190-4

Experimental method

X-RAY DIFFRACTION (1.98 Å)