Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0035556 | biological_process | intracellular signal transduction |
B | 0006368 | biological_process | transcription elongation by RNA polymerase II |
B | 0030891 | cellular_component | VCB complex |
B | 0070449 | cellular_component | elongin complex |
C | 0006511 | biological_process | ubiquitin-dependent protein catabolic process |
D | 0035556 | biological_process | intracellular signal transduction |
E | 0006368 | biological_process | transcription elongation by RNA polymerase II |
E | 0030891 | cellular_component | VCB complex |
E | 0070449 | cellular_component | elongin complex |
F | 0006511 | biological_process | ubiquitin-dependent protein catabolic process |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 6 |
Details | binding site for residue CO A 201 |
Chain | Residue |
A | HIS149 |
A | HOH338 |
A | HOH365 |
A | HOH383 |
K | HIS4 |
K | HOH108 |
site_id | AC2 |
Number of Residues | 3 |
Details | binding site for residue CO D 201 |
Chain | Residue |
D | HIS149 |
L | SER2 |
L | HIS4 |
site_id | AC3 |
Number of Residues | 5 |
Details | binding site for residue SO4 D 202 |
Chain | Residue |
D | GLN45 |
D | SER162 |
D | ARG168 |
D | TYR190 |
D | HOH339 |
site_id | AC4 |
Number of Residues | 18 |
Details | binding site for Di-peptide PTR I 0 and THR I 1 |
Chain | Residue |
A | VAL55 |
A | ARG73 |
A | SER75 |
A | SER76 |
A | THR83 |
A | THR93 |
A | ASN94 |
A | LEU95 |
A | ARG96 |
I | VAL-3 |
I | PRO-2 |
I | ASP-1 |
I | SER2 |
I | HOH101 |
I | HOH102 |
K | ILE5 |
K | VLM6 |
K | HOH106 |
site_id | AC5 |
Number of Residues | 6 |
Details | binding site for Di-peptide ILE I 5 and VLM I 6 |
Chain | Residue |
A | HOH361 |
C | MET45 |
I | HIS4 |
I | HOH104 |
K | SER2 |
K | ILE3 |
site_id | AC6 |
Number of Residues | 14 |
Details | binding site for Di-peptide ASP I -1 and PTR I 0 |
Chain | Residue |
A | VAL55 |
A | ARG73 |
A | SER75 |
A | SER76 |
A | THR83 |
A | THR93 |
A | ASN94 |
A | ARG96 |
A | HOH351 |
I | PRO-2 |
I | THR1 |
I | HOH102 |
I | HOH103 |
K | HOH106 |
site_id | AC7 |
Number of Residues | 16 |
Details | binding site for Di-peptide PTR J 0 and THR J 1 |
Chain | Residue |
D | VAL55 |
D | ARG73 |
D | SER75 |
D | SER76 |
D | THR83 |
D | THR93 |
D | ASN94 |
D | LEU95 |
D | ARG96 |
J | VAL-3 |
J | PRO-2 |
J | ASP-1 |
J | SER2 |
J | HOH101 |
L | ILE5 |
L | VLM6 |
site_id | AC8 |
Number of Residues | 10 |
Details | binding site for Di-peptide ASP J -1 and PTR J 0 |
Chain | Residue |
D | VAL55 |
D | ARG73 |
D | SER75 |
D | SER76 |
D | THR83 |
D | THR93 |
D | ASN94 |
D | ARG96 |
J | PRO-2 |
J | THR1 |
site_id | AC9 |
Number of Residues | 12 |
Details | binding site for Di-peptide PTR K 0 and THR K 1 |
Chain | Residue |
A | MET132 |
A | CAS133 |
A | ASP135 |
A | LYS136 |
A | HIS149 |
A | HOH367 |
K | ASP-1 |
K | PRO-2 |
K | SER2 |
K | ILE3 |
K | HOH104 |
K | HOH107 |
site_id | AD1 |
Number of Residues | 11 |
Details | binding site for Di-peptide ILE K 5 and VLM K 6 |
Chain | Residue |
K | HOH106 |
K | HOH109 |
A | THR88 |
A | ILE109 |
A | VAL148 |
I | THR1 |
I | SER2 |
I | ILE3 |
K | HIS4 |
K | HOH102 |
K | HOH103 |
site_id | AD2 |
Number of Residues | 11 |
Details | binding site for Di-peptide ASP K -1 and PTR K 0 |
Chain | Residue |
A | MET132 |
A | ASP135 |
A | LYS136 |
A | HIS149 |
A | HOH367 |
K | PRO-2 |
K | VAL-3 |
K | THR1 |
K | SER2 |
K | HOH107 |
K | HOH110 |
site_id | AD3 |
Number of Residues | 7 |
Details | binding site for Di-peptide PTR L 0 and THR L 1 |
Chain | Residue |
D | MET132 |
D | CAS133 |
D | HIS149 |
L | PRO-2 |
L | ASP-1 |
L | SER2 |
L | ILE3 |
site_id | AD4 |
Number of Residues | 7 |
Details | binding site for Di-peptide ILE L 5 and VLM L 6 |
Chain | Residue |
D | VAL148 |
D | LEU150 |
J | THR1 |
J | SER2 |
J | ILE3 |
L | HIS4 |
L | HOH101 |
site_id | AD5 |
Number of Residues | 6 |
Details | binding site for Di-peptide ASP L -1 and PTR L 0 |
Chain | Residue |
D | MET132 |
D | CAS133 |
D | HIS149 |
L | PRO-2 |
L | THR1 |
L | HOH102 |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
B | MET1 | |
E | MET1 | |
Chain | Residue | Details |
B | THR84 | |
E | THR84 | |
site_id | SWS_FT_FI3 |
Number of Residues | 4 |
Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:31578312 |
Chain | Residue | Details |
A | LYS173 | |
D | LYS173 | |