7M2I
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7M7E
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![BU of 7m7e by Molmil](/molmil-images/mine/7m7e) | 6-Deoxyerythronolide B synthase (DEBS) hybrid module (M3/1) in complex with antibody fragment 1B2 | Descriptor: | 1B2 (heavy chain), 1B2 (light chain), 6-deoxyerythronolide-B synthase EryA2, ... | Authors: | Cogan, D.P, Zhang, K, Chiu, W, Khosla, C. | Deposit date: | 2021-03-28 | Release date: | 2021-11-17 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Mapping the catalytic conformations of an assembly-line polyketide synthase module. Science, 374, 2021
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7M7G
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![BU of 7m7g by Molmil](/molmil-images/mine/7m7g) | 6-Deoxyerythronolide B synthase (DEBS) module 1 in complex with antibody fragment 1B2: State 2 | Descriptor: | 1B2 (heavy chain), 1B2 (light chain), EryAI,6-deoxyerythronolide-B synthase EryA3, ... | Authors: | Cogan, D.P, Zhang, K, Chiu, W, Khosla, C. | Deposit date: | 2021-03-28 | Release date: | 2021-11-17 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Mapping the catalytic conformations of an assembly-line polyketide synthase module. Science, 374, 2021
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7M7H
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![BU of 7m7h by Molmil](/molmil-images/mine/7m7h) | 6-Deoxyerythronolide B synthase (DEBS) module 1 in complex with antibody fragment 1B2: State 1' | Descriptor: | 1B2 (heavy chain), 1B2 (light chain), EryAI,6-deoxyerythronolide-B synthase EryA3, ... | Authors: | Cogan, D.P, Zhang, K, Chiu, W, Khosla, C. | Deposit date: | 2021-03-28 | Release date: | 2021-11-17 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Mapping the catalytic conformations of an assembly-line polyketide synthase module. Science, 374, 2021
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7M7I
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![BU of 7m7i by Molmil](/molmil-images/mine/7m7i) | 6-Deoxyerythronolide B synthase (DEBS) module 1 in complex with antibody fragment 1B2 (TE-free) | Descriptor: | 1B2 (heavy chain), 1B2 (light chain), EryAI, ... | Authors: | Cogan, D.P, Zhang, K, Chiu, W, Khosla, C. | Deposit date: | 2021-03-28 | Release date: | 2021-11-17 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Mapping the catalytic conformations of an assembly-line polyketide synthase module. Science, 374, 2021
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7M7J
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![BU of 7m7j by Molmil](/molmil-images/mine/7m7j) | 6-Deoxyerythronolide B synthase (DEBS) module 1 in complex with antibody fragment 1B2: "turnstile closed" state (TE-free) | Descriptor: | 1B2 (heavy chain), 1B2 (light chain), EryAI | Authors: | Cogan, D.P, Zhang, K, Chiu, W, Khosla, C. | Deposit date: | 2021-03-28 | Release date: | 2021-11-17 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Mapping the catalytic conformations of an assembly-line polyketide synthase module. Science, 374, 2021
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7M7F
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![BU of 7m7f by Molmil](/molmil-images/mine/7m7f) | 6-Deoxyerythronolide B synthase (DEBS) module 1 in complex with antibody fragment 1B2: State 1 | Descriptor: | 1B2 (heavy chain), 1B2 (light chain), EryAI,6-deoxyerythronolide-B synthase EryA3, ... | Authors: | Cogan, D.P, Zhang, K, Chiu, W, Khosla, C. | Deposit date: | 2021-03-28 | Release date: | 2021-11-17 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Mapping the catalytic conformations of an assembly-line polyketide synthase module. Science, 374, 2021
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7PIU
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![BU of 7piu by Molmil](/molmil-images/mine/7piu) | Cryo-EM structure of the agonist setmelanotide bound to the active melanocortin-4 receptor (MC4R) in complex with the heterotrimeric Gs protein at 2.6 A resolution. | Descriptor: | CALCIUM ION, Camelid antibody fragment - nanobody 35, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Heyder, N.A, Schmidt, A, Kleinau, G, Hilal, T, Scheerer, P. | Deposit date: | 2021-08-23 | Release date: | 2021-11-17 | Method: | ELECTRON MICROSCOPY (2.58 Å) | Cite: | Structures of active melanocortin-4 receptor-Gs-protein complexes with NDP-alpha-MSH and setmelanotide. Cell Res., 31, 2021
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7PIV
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![BU of 7piv by Molmil](/molmil-images/mine/7piv) | Active Melanocortin-4 receptor (MC4R)- Gs protein complex bound to agonist NDP-alpha-MSH at 2.86 A resolution. | Descriptor: | CALCIUM ION, Camelid antibody VHH fragment - nanobody 35, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Heyder, N.A, Schmidt, A, Kleinau, G, Hilal, T, Scheerer, P. | Deposit date: | 2021-08-23 | Release date: | 2021-11-17 | Method: | ELECTRON MICROSCOPY (2.86 Å) | Cite: | Structures of active melanocortin-4 receptor-Gs-protein complexes with NDP-alpha-MSH and setmelanotide. Cell Res., 31, 2021
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7LI9
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![BU of 7li9 by Molmil](/molmil-images/mine/7li9) | |
7LIA
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5WCD
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![BU of 5wcd by Molmil](/molmil-images/mine/5wcd) | Crystal structure of the broadly neutralizing Influenza A antibody VRC 315 04-1D02 Fab. | Descriptor: | PHOSPHATE ION, SULFATE ION, VRC315 04-1D02 Fab Heavy chain, ... | Authors: | Joyce, M.G, Andrews, S.F, Mascola, J.R, McDermott, A.B, Kwong, P.D. | Deposit date: | 2017-06-29 | Release date: | 2017-08-23 | Last modified: | 2018-11-28 | Method: | X-RAY DIFFRACTION (1.814 Å) | Cite: | Preferential induction of cross-group influenza A hemagglutinin stem-specific memory B cells after H7N9 immunization in humans. Sci Immunol, 2, 2017
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7LJ5
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7LJB
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7LJA
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7LJ4
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7VAF
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![BU of 7vaf by Molmil](/molmil-images/mine/7vaf) | Cryo-EM structure of Rat NTCP complexed with YN69202Fab | Descriptor: | Fab heavy chain from antibody IgG clone number YN69202, Fab light chain from antibody IgG clone number YN69202, Sodium/bile acid cotransporter | Authors: | Asami, J, Shimizu, T, Ohto, U. | Deposit date: | 2021-08-29 | Release date: | 2022-05-25 | Last modified: | 2022-07-13 | Method: | ELECTRON MICROSCOPY (3.11 Å) | Cite: | Structure of the bile acid transporter and HBV receptor NTCP. Nature, 606, 2022
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7VAG
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7VAD
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![BU of 7vad by Molmil](/molmil-images/mine/7vad) | Cryo-EM structure of human NTCP complexed with YN69202Fab | Descriptor: | Fab heavy chain from antibody IgG clone number YN69202, Fab light chain from antibody IgG clone number YN69202, Sodium/bile acid cotransporter | Authors: | Asami, J, Shimizu, T, Ohto, U. | Deposit date: | 2021-08-29 | Release date: | 2022-05-25 | Last modified: | 2022-07-13 | Method: | ELECTRON MICROSCOPY (3.41 Å) | Cite: | Structure of the bile acid transporter and HBV receptor NTCP. Nature, 606, 2022
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7VAE
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![BU of 7vae by Molmil](/molmil-images/mine/7vae) | Cryo-EM structure of bovine NTCP complexed with YN69202Fab | Descriptor: | Fab heavy chain from antibody IgG clone number YN69202, Fab light chain from antibody IgG clone number YN69202, Solute carrier family 10 (Sodium/bile acid cotransporter family), ... | Authors: | Asami, J, Shimizu, T, Ohto, U. | Deposit date: | 2021-08-29 | Release date: | 2022-05-25 | Last modified: | 2022-07-13 | Method: | ELECTRON MICROSCOPY (3.55 Å) | Cite: | Structure of the bile acid transporter and HBV receptor NTCP. Nature, 606, 2022
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5VGA
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![BU of 5vga by Molmil](/molmil-images/mine/5vga) | Alternative model for Fab 36-65 | Descriptor: | Fab 36-65 heavy chain, Fab 36-65 light chain, TRIETHYLENE GLYCOL | Authors: | Stanfield, R.L, Rupp, B, Wlodawer, A, Dauter, Z, Porebski, P.J, Minor, W, Jaskolski, M, Pozharski, E, Weichenberger, C.X. | Deposit date: | 2017-04-10 | Release date: | 2017-12-06 | Last modified: | 2022-04-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Detect, correct, retract: How to manage incorrect structural models. FEBS J., 285, 2018
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2Y7S
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2MCP
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5WCA
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![BU of 5wca by Molmil](/molmil-images/mine/5wca) | Crystal structure of the broadly neutralizing Influenza A antibody VRC 315 27-1C08 Fab. | Descriptor: | VRC315 27-1C08 Fab Heavy chain, VRC315 27-1C08 Fab Light chain | Authors: | Joyce, M.G, Andrews, S.F, Mascola, J.R, McDermott, A.B, Kwong, P.D. | Deposit date: | 2017-06-29 | Release date: | 2017-08-02 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.369 Å) | Cite: | Preferential induction of cross-group influenza A hemagglutinin stem-specific memory B cells after H7N9 immunization in humans. Sci Immunol, 2, 2017
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7O7F
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![BU of 7o7f by Molmil](/molmil-images/mine/7o7f) | Structural basis of the activation of the CC chemokine receptor 5 by a chemokine agonist | Descriptor: | C-C chemokine receptor type 5, C-C motif chemokine 5, Fab antibody fragment heavy chain, ... | Authors: | Isaikina, P, Tsai, C.-J, Dietz, N.B, Pamula, F, Goldie, K.N, Schertler, G.F.X, Maier, T, Stahlberg, H, Deupi, X, Grzesiek, S. | Deposit date: | 2021-04-13 | Release date: | 2021-06-30 | Last modified: | 2022-03-16 | Method: | ELECTRON MICROSCOPY (3.15 Å) | Cite: | Structural basis of the activation of the CC chemokine receptor 5 by a chemokine agonist. Sci Adv, 7, 2021
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