7LIA

5-HT bound serotonin transporter reconstituted in lipid nanodisc in presence of NaCl in outward facing conformation

Summary for 7LIA

• Entry DOI: 10.2210/pdb7lia/pdb
• EMDB information: 23365
• Descriptor: Sodium-dependent serotonin transporter, PENTANE, CHOLESTEROL, ... (11 entities in total)
• Functional Keywords: serotonin, outward open, serotonin transporter, fab, membrane protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 88963.66

Authors

Yang, D.,Gouaux, E. (deposition date: 2021-01-26, release date: 2021-12-15)

• Primary citation: Yang, D.,Gouaux, E.; Illumination of serotonin transporter mechanism and role of the allosteric site.; Sci Adv, 7:eabl3857-eabl3857, 2021; PubMed: 34851672; DOI: 10.1126/sciadv.abl3857

Experimental method

ELECTRON MICROSCOPY (3.3 Å)