7LIA
5-HT bound serotonin transporter reconstituted in lipid nanodisc in presence of NaCl in outward facing conformation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Sodium-dependent serotonin transporter | polymer | 539 | 60876.0 | 1 | UniProt (P31645) Pfam (PF00209) | Homo sapiens (Human) | SERT,5HT transporter,5HTT,Solute carrier family 6 member 4 |
| 2 | B (B) | variable domain of 15B8 antibody Fab heavy chain | polymer | 118 | 12980.5 | 1 | Mus musculus (mouse) | ||
| 3 | C (C) | variable domain of 15B8 antibody Fab light chain | polymer | 110 | 11776.1 | 1 | Mus musculus (mouse) | ||
| 4 | D (D) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 5 | E, I (A) | SEROTONIN | non-polymer | 176.2 | 2 | Chemie (SRO) | |||
| 6 | F (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 7 | G, H (A) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 8 | AA, BA, J, V, W (A) | DECANE | non-polymer | 142.3 | 5 | Chemie (D10) | |||
| 9 | K, L, M, N, O... (A) | HEPTANE | non-polymer | 100.2 | 13 | Chemie (HP6) | |||
| 10 | U (A) | PENTANE | non-polymer | 72.1 | 1 | Chemie (LNK) | |||
| 11 | CA (A) | CHOLESTEROL | non-polymer | 386.7 | 1 | Chemie (CLR) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 85632.6 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 25 |
| Total formula weight | 2906.7 | |
| All* | Total formula weight | 88963.7 |
