7VAE

Cryo-EM structure of bovine NTCP complexed with YN69202Fab

Summary for 7VAE

Entry DOI	10.2210/pdb7vae/pdb
EMDB information	31838
Descriptor	Solute carrier family 10 (Sodium/bile acid cotransporter family), member 1, Fab heavy chain from antibody IgG clone number YN69202, Fab light chain from antibody IgG clone number YN69202 (3 entities in total)
Functional Keywords	hepatitis b virus (hbv), host entry receptor, bile acid transporter, taurocholate, na+-coupled symporter, transport protein
Biological source	Bos taurus (Bovine) More
Total number of polymer chains	3
Total formula weight	89004.08
Authors	Asami, J.,Shimizu, T.,Ohto, U. (deposition date: 2021-08-29, release date: 2022-05-25, Last modification date: 2022-07-13)
Primary citation	Asami, J.,Kimura, K.T.,Fujita-Fujiharu, Y.,Ishida, H.,Zhang, Z.,Nomura, Y.,Liu, K.,Uemura, T.,Sato, Y.,Ono, M.,Yamamoto, M.,Noda, T.,Shigematsu, H.,Drew, D.,Iwata, S.,Shimizu, T.,Nomura, N.,Ohto, U. Structure of the bile acid transporter and HBV receptor NTCP. Nature, 606:1021-1026, 2022 Cited by PubMed: 35580629 DOI: 10.1038/s41586-022-04845-4 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.55 Å)

Structure validation