2Y7S

Structure of a designed meningococcal antigen (factor H binding protein, mutant G1) inducing broad protective immunity

Summary for 2Y7S

Entry DOI	10.2210/pdb2y7s/pdb
Related	2W80 2W81
Descriptor	FACTOR H BINDING PROTEIN (2 entities in total)
Functional Keywords	immune system, antigen, epitope, antibody, structure-based design, vaccine
Biological source	NEISSERIA MENINGITIDIS SEROGROUP B
Total number of polymer chains	2
Total formula weight	55437.79
Authors	Malito, E.,Spraggon, G.,Bottomley, M.J. (deposition date: 2011-02-01, release date: 2011-07-27, Last modification date: 2023-12-20)
Primary citation	Scarselli, M.,Arico, B.,Brunelli, B.,Savino, S.,Di Marcello, F.,Palumbo, E.,Veggi, D.,Ciucchi, L.,Cartocci, E.,Bottomley, M.J.,Malito, E.,Lo Surdo, P.,Comanducci, M.,Giuliani, M.M.,Cantini, F.,Dragonetti, S.,Colaprico, A.,Doro, F.,Giannetti, P.,Pallaoro, M.,Brogioni, B.,Tontini, M.,Hilleringmann, M.,Nardi-Dei, V.,Banci, L.,Pizza, M.,Rappuoli, R. Rational Design of a Meningococcal Antigen Inducing Broad Protective Immunity. Sci.Transl.Med, 3:91RA6-, 2011 Cited by PubMed: 21753121 DOI: 10.1126/SCITRANSLMED.3002234 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation