7LI9

5-HT bound serotonin transporter reconstituted in lipid nanodisc in KCl

Summary for 7LI9

• Entry DOI: 10.2210/pdb7li9/pdb
• EMDB information: 23364
• Descriptor: Sodium-dependent serotonin transporter, CHLORIDE ION, variable domain of 15B8 antibody Fab heavy chain, ... (10 entities in total)
• Functional Keywords: serotonin, transport, kcl, inward, membrane protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 87484.91

Authors

Yang, D.,Gouaux, E. (deposition date: 2021-01-26, release date: 2021-12-15)

• Primary citation: Yang, D.,Gouaux, E.; Illumination of serotonin transporter mechanism and role of the allosteric site.; Sci Adv, 7:eabl3857-eabl3857, 2021; PubMed: 34851672; DOI: 10.1126/sciadv.abl3857

Experimental method

ELECTRON MICROSCOPY (3.9 Å)