PDB: 8861 resultsInfo pagesStatus searchChemie searchBIRD

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4RAU	crystal structure of RTOFab in complex with human PF4 Descriptor: Platelet factor 4, RTOFab heavy chain, RTOFab light chain Authors: Cai, Z, Zhu, Z, Liu, Q, Greene, M.I. Deposit date: 2014-09-11 Release date: 2016-03-16 Method: X-RAY DIFFRACTION (3.74 Å) Cite: crystal structure of RTOFab in complex with platelet factor 4 To be Published
8SJD	Cryo-EM structure of the Hermes transposase bound to two right-ends of its DNA transposon. Descriptor: DNA (46-MER), DNA (55-MER), DNA (8-MER), ... Authors: Lannes, L, Dyda, F. Deposit date: 2023-04-17 Release date: 2023-08-02 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (5.1 Å) Cite: Zinc-finger BED domains drive the formation of the active Hermes transpososome by asymmetric DNA binding. Nat Commun, 14, 2023
1CF7	STRUCTURAL BASIS OF DNA RECOGNITION BY THE HETERODIMERIC CELL CYCLE TRANSCRIPTION FACTOR E2F-DP Descriptor: DNA (5'-D(*AP*TP*TP*TP*TP*CP*GP*CP*GP*CP*GP*GP*TP*TP*TP*T)-3'), DNA (5'-D(*TP*AP*AP*AP*AP*CP*CP*GP*CP*GP*CP*GP*AP*AP*AP*A)-3'), PROTEIN (TRANSCRIPTION FACTOR DP-2), ... Authors: Zheng, N, Fraenkel, E, Pabo, C.O, Pavletich, N.P. Deposit date: 1999-03-24 Release date: 1999-04-02 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structural basis of DNA recognition by the heterodimeric cell cycle transcription factor E2F-DP. Genes Dev., 13, 1999
3PSI	Crystal Structure of the Spt6 core domain from Saccharomyces cerevisiae, Form Spt6(239-1451) Descriptor: Transcription elongation factor SPT6 Authors: Close, D, Hill, C.P, Johnson, S.J. Deposit date: 2010-12-01 Release date: 2011-03-30 Last modified: 2011-08-03 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Crystal structures of the S. cerevisiae Spt6 core and C-terminal tandem SH2 domain. J.Mol.Biol., 408, 2011
3PSF	Crystal Structure of the Spt6 core domain from Saccharomyces cerevisiae, Form Spt6(236-1259) Descriptor: Transcription elongation factor SPT6 Authors: Close, D, Hill, C.P. Deposit date: 2010-12-01 Release date: 2011-03-30 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.59 Å) Cite: Crystal structures of the S. cerevisiae Spt6 core and C-terminal tandem SH2 domain. J.Mol.Biol., 408, 2011
5FR1	Double acetylated RhoGDI-alpha in complex with RhoA-GDP Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RHO GDP-DISSOCIATION INHIBITOR 1, ... Authors: Kuhlmann, N, Wroblowski, S, Lammers, M. Deposit date: 2015-12-15 Release date: 2016-01-13 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Rhogdi Alpha Acetylation at K127 and K141 Affects Binding Towards Non-Prenylated Rhoa. Biochemistry, 55, 2016
7EFA	Crystal structure of the complex between the C-terminal domain of mouse MUTYH and human PCNA Descriptor: Adenine DNA glycosylase, Proliferating cell nuclear antigen Authors: Nakamura, T, Nakabeppu, Y, Yamagata, Y. Deposit date: 2021-03-21 Release date: 2021-06-23 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structure of the mammalian adenine DNA glycosylase MUTYH: insights into the base excision repair pathway and cancer. Nucleic Acids Res., 49, 2021
5SXM	WDR5 in complex with MLL Win motif peptidomimetic Descriptor: ACE-ALA-ARG-THR-GLU-VAL-TYR-NH2, WD repeat-containing protein 5 Authors: Alicea-Velazquez, N.L, Shinsky, S.A, Cosgrove, M.S. Deposit date: 2016-08-09 Release date: 2016-09-07 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2 Å) Cite: Targeted Disruption of the Interaction between WD-40 Repeat Protein 5 (WDR5) and Mixed Lineage Leukemia (MLL)/SET1 Family Proteins Specifically Inhibits MLL1 and SETd1A Methyltransferase Complexes. J.Biol.Chem., 291, 2016
3PSJ	Crystal Structure of the Spt6 Tandem SH2 Domain from Saccharomyces cerevisiae, Form Se-Spt6 (1247-1451) Descriptor: SULFATE ION, Transcription elongation factor SPT6 Authors: Close, D, Hill, C.P. Deposit date: 2010-12-01 Release date: 2011-03-30 Last modified: 2017-11-08 Method: X-RAY DIFFRACTION (2.702 Å) Cite: Crystal structures of the S. cerevisiae Spt6 core and C-terminal tandem SH2 domain. J.Mol.Biol., 408, 2011
6FCM	Crystal structure of human PCNA Descriptor: Proliferating cell nuclear antigen Authors: Housset, D, Frachet, P. Deposit date: 2017-12-20 Release date: 2019-01-30 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Cytosolic PCNA interacts with p47phox and controls NADPH oxidase NOX2 activation in neutrophils. J.Exp.Med., 216, 2019
6WGE	Cryo-EM structure of human Cohesin-NIPBL-DNA complex without STAG1 Descriptor: DNA (43-MER), Double-strand-break repair protein rad21 homolog, MAGNESIUM ION, ... Authors: Shi, Z.B, Gao, H, Bai, X.C, Yu, H. Deposit date: 2020-04-05 Release date: 2020-05-20 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Cryo-EM structure of the human cohesin-NIPBL-DNA complex. Science, 368, 2020
6FCN	Crystal structure of human PCNA soaked with p47phox(106-127) peptide Descriptor: Proliferating cell nuclear antigen Authors: Housset, D, Frachet, P. Deposit date: 2017-12-20 Release date: 2019-01-30 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (3.22 Å) Cite: Cytosolic PCNA interacts with p47phox and controls NADPH oxidase NOX2 activation in neutrophils. J.Exp.Med., 216, 2019
7RPW	Archaeal DNA ligase and heterotrimeric PCNA in complex with adenylated DNA Descriptor: ADENOSINE MONOPHOSPHATE, DNA ligase, DNA polymerase sliding clamp 1, ... Authors: Sverzhinsky, A, Pascal, J.M. Deposit date: 2021-08-04 Release date: 2021-11-17 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (4.38 Å) Cite: Cryo-EM structures and biochemical insights into heterotrimeric PCNA regulation of DNA ligase. Structure, 30, 2022
7RPO	Archaeal DNA ligase and heterotrimeric PCNA in complex with non-ligatable DNA Descriptor: ADENOSINE MONOPHOSPHATE, DNA ligase, DNA polymerase sliding clamp 1, ... Authors: Sverzhinsky, A, Pascal, J.M. Deposit date: 2021-08-03 Release date: 2021-11-17 Last modified: 2022-03-16 Method: ELECTRON MICROSCOPY (4.16 Å) Cite: Cryo-EM structures and biochemical insights into heterotrimeric PCNA regulation of DNA ligase. Structure, 30, 2022
7RPX	Archaeal DNA ligase and heterotrimeric PCNA in complex with end-joined DNA Descriptor: DNA ligase, DNA polymerase sliding clamp 1, DNA polymerase sliding clamp 2, ... Authors: Sverzhinsky, A, Pascal, J.M. Deposit date: 2021-08-04 Release date: 2021-11-17 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Cryo-EM structures and biochemical insights into heterotrimeric PCNA regulation of DNA ligase. Structure, 30, 2022
5XY9	Structure of the MST4 and 14-3-3 complex Descriptor: 14-3-3 protein zeta/delta, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, GLYCEROL, ... Authors: Shi, Z.B, Zhou, Z.C. Deposit date: 2017-07-06 Release date: 2018-07-11 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.303 Å) Cite: Structure of the MST4 and 14-3-3 complex To Be Published
5UTZ	Human IL-2/Fab complex Descriptor: Fab 5111 heavy chain, Fab 5111 light chain, GLYCEROL, ... Authors: Jude, K.M, Garcia, K.C. Deposit date: 2017-02-15 Release date: 2018-07-11 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.747 Å) Cite: A human anti-IL-2 antibody that potentiates regulatory T cells by a structure-based mechanism. Nat. Med., 24, 2018
8RTY	Structure of the F-actin barbed end bound by Cdc12 and profilin (ring complex) at a resolution of 6.3 Angstrom Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... Authors: Oosterheert, W, Boiero Sanders, M, Funk, J, Prumbaum, D, Raunser, S, Bieling, P. Deposit date: 2024-01-29 Release date: 2024-04-10 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (6.25 Å) Cite: Molecular mechanism of actin filament elongation by formins. Science, 384, 2024
7DR4	Complex of anti-human IL-2 antibody and human IL-2 Descriptor: Interleukin-2, anti-human IL-2 antibody, mouse Ig G, ... Authors: Kim, M.S, Kim, J.E. Deposit date: 2020-12-25 Release date: 2021-04-14 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.49 Å) Cite: Crystal structure of human interleukin-2 in complex with TCB2, a new antibody-drug candidate with antitumor activity. Oncoimmunology, 10, 2021
6MEV	Structure of JMJD6 bound to Mono-Methyl Arginine. Descriptor: (2S)-2-amino-5-[(N-methylcarbamimidoyl)amino]pentanoic acid, 2-OXOGLUTARIC ACID, Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6, ... Authors: Lee, S, Zhang, G. Deposit date: 2018-09-07 Release date: 2019-09-18 Last modified: 2020-04-01 Method: X-RAY DIFFRACTION (2.6 Å) Cite: JMJD6 cleaves MePCE to release positive transcription elongation factor b (P-TEFb) in higher eukaryotes. Elife, 9, 2020
7Q3O	Structure of CDX1 bound to hydroxymethylated DNA Descriptor: Homeobox protein CDX-1, hydroxymethylated DNA (18-MER) Authors: Morgunova, E, Yin, Y, Popov, A, Taipale, J. Deposit date: 2021-10-28 Release date: 2022-11-16 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.78 Å) Cite: Structure of CDX1 bound to hydroxymethylated DNA To Be Published
3QEX	RB69 DNA Polymerase (L561A/S565G/Y567A) Ternary Complex with dGTP Opposite dT Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ... Authors: Xia, S, Konigsberg, W.H, Wang, J. Deposit date: 2011-01-20 Release date: 2012-01-25 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.73 Å) Cite: Hydrogen-Bonding Capability of Difluorotoluene Nucleoside in Replication Complexes To be Published
8UQE	Crystal structure of RNF168 (RING)-UbcH5c fused to H2A-H2B via a 26-residue linker (RING not modeled in density) Descriptor: E3 ubiquitin-protein ligase RNF168,Ubiquitin-conjugating enzyme E2 D3,Histone H2B type 2-E,Histone H2A type 1-B/E Authors: Hu, Q, Botuyan, M.V, Mer, G. Deposit date: 2023-10-23 Release date: 2024-01-17 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (3.562 Å) Cite: Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
8UQA	Crystal structure of RNF168 (RING)-UbcH5c fused to H2A-H2B via a 12-residue linker Descriptor: CHLORIDE ION, E3 ubiquitin-protein ligase RNF168,Ubiquitin-conjugating enzyme E2 D3,Histone H2B type 2-E,Histone H2A type 1-B/E, SODIUM ION, ... Authors: Hu, Q, Botuyan, M.V, Mer, G. Deposit date: 2023-10-23 Release date: 2024-01-17 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.049 Å) Cite: Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
8UQB	Crystal structure of RNF168 (RING)-UbcH5c fused to H2A-H2B via a 20-residue linker (crystallization condition 1) Descriptor: CHLORIDE ION, E3 ubiquitin-protein ligase RNF168,Ubiquitin-conjugating enzyme E2 D3,Histone H2B type 2-E,Histone H2A type 1-B/E, ZINC ION Authors: Hu, Q, Botuyan, M.V, Mer, G. Deposit date: 2023-10-23 Release date: 2024-01-17 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.484 Å) Cite: Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024

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