6WGE

Cryo-EM structure of human Cohesin-NIPBL-DNA complex without STAG1

Summary for 6WGE

• Entry DOI: 10.2210/pdb6wge/pdb
• EMDB information: 21663
• Descriptor: Structural maintenance of chromosomes protein 1A, Structural maintenance of chromosomes protein 3, Double-strand-break repair protein rad21 homolog, ... (8 entities in total)
• Functional Keywords: protein-dna complex, atpase, dna-binding protein, genome organization, sister chromatid cohesion, transcription regulation, cell cycle, cell cycle-dna complex, cell cycle/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 571108.31

Authors

Shi, Z.B.,Gao, H.,Bai, X.C.,Yu, H. (deposition date: 2020-04-05, release date: 2020-05-20, Last modification date: 2024-03-06)

• Primary citation: Shi, Z.,Gao, H.,Bai, X.C.,Yu, H.; Cryo-EM structure of the human cohesin-NIPBL-DNA complex.; Science, 368:1454-1459, 2020; PubMed: 32409525; DOI: 10.1126/science.abb0981

Experimental method

ELECTRON MICROSCOPY (3.9 Å)