5FR1

Double acetylated RhoGDI-alpha in complex with RhoA-GDP

Summary for 5FR1

Related5FR2
DescriptorTRANSFORMING PROTEIN RHOA, RHO GDP-DISSOCIATION INHIBITOR 1, GUANOSINE-5'-DIPHOSPHATE, ... (5 entities in total)
Functional Keywordssignaling protein, ras-superfamily, guanine-nucleotide-binding protein, molecular switch, actin-cytoskeleton rhogdi-alpha, nucleotide dissociation, prenylation, lysine-acetylation
Biological sourceHOMO SAPIENS (HUMAN)
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Total number of polymer chains2
Total molecular weight47221.21
Authors
Kuhlmann, N.,Wroblowski, S.,Lammers, M. (deposition date: 2015-12-15, release date: 2016-01-13, Last modification date: 2019-10-16)
Primary citation
Kuhlmann, N.,Wroblowski, S.,Scislowski, L.,Lammers, M.
Rhogdi Alpha Acetylation at K127 and K141 Affects Binding Towards Non-Prenylated Rhoa.
Biochemistry, 55:304-, 2016
PubMed: 26695096 (PDB entries with the same primary citation)
DOI: 10.1021/ACS.BIOCHEM.5B01242
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.75 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.228600 4.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
171916
PDB entries from 2020-12-02