8RTY

Structure of the F-actin barbed end bound by Cdc12 and profilin (ring complex) at a resolution of 6.3 Angstrom

This is a non-PDB format compatible entry.

Summary for 8RTY

• Entry DOI: 10.2210/pdb8rty/pdb
• Related: 8RTT
• EMDB information: 19496 19497 19499
• Related PRD ID: PRD_002366
• Descriptor: Actin, cytoplasmic 1, N-terminally processed, Methylated-DNA--protein-cysteine methyltransferase,Cell division control protein 12, Phalloidin (Amanita phalloides), ... (7 entities in total)
• Functional Keywords: actin, formin, cdc12, profilin, actin assembly, structural protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 10
• Total formula weight: 341825.17

Authors

Oosterheert, W.,Boiero Sanders, M.,Funk, J.,Prumbaum, D.,Raunser, S.,Bieling, P. (deposition date: 2024-01-29, release date: 2024-04-10, Last modification date: 2024-04-24)

• Primary citation: Oosterheert, W.,Boiero Sanders, M.,Funk, J.,Prumbaum, D.,Raunser, S.,Bieling, P.; Molecular mechanism of actin filament elongation by formins.; Science, 384:eadn9560-eadn9560, 2024; PubMed: 38603491; DOI: 10.1126/science.adn9560

Experimental method

ELECTRON MICROSCOPY (6.25 Å)