8RTT
Structure of the formin Cdc12 bound to the barbed end of phalloidin-stabilized F-actin.
Summary for 8RTT
| Entry DOI | 10.2210/pdb8rtt/pdb |
| EMDB information | 19496 |
| Related PRD ID | PRD_002366 |
| Descriptor | Actin, cytoplasmic 1, N-terminally processed, Cell division control protein 12, Phalloidin, ... (6 entities in total) |
| Functional Keywords | actin, formin, cdc12, actin assembly., structural protein |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 9 |
| Total formula weight | 268562.59 |
| Authors | Oosterheert, W.,Boiero Sanders, M.,Funk, J.,Prumbaum, D.,Raunser, S.,Bieling, P. (deposition date: 2024-01-29, release date: 2024-04-10, Last modification date: 2024-06-05) |
| Primary citation | Oosterheert, W.,Boiero Sanders, M.,Funk, J.,Prumbaum, D.,Raunser, S.,Bieling, P. Molecular mechanism of actin filament elongation by formins. Science, 384:eadn9560-eadn9560, 2024 Cited by PubMed: 38603491DOI: 10.1126/science.adn9560 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.56 Å) |
Structure validation
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