8RTT
Structure of the formin Cdc12 bound to the barbed end of phalloidin-stabilized F-actin.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Actin, cytoplasmic 1, N-terminally processed | polymer | 375 | 41763.6 | 4 | UniProt (P60709) Pfam (PF00022) | Homo sapiens (human) | |
| 2 | E, I (E, F) | Cell division control protein 12 | polymer | 419 | 48495.2 | 2 | UniProt (Q10059) Pfam (PF02181) | Schizosaccharomyces pombe (fission yeast) | |
| 3 | F, G, H (H, I, J) | Phalloidin | polymer | 7 | 808.9 | 3 | BIRD (PRD_002366) | Amanita phalloides | |
| 4 | J, M, P, S (A, B, C, D) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 4 | Chemie (ADP) | |||
| 5 | K, N, Q, T (A, B, C, D) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 6 | L, O, R (A, B, C) | PHOSPHATE ION | non-polymer | 95.0 | 3 | Chemie (PO4) |
Sequence modifications
A, B, C, D: 1 - 375 (UniProt: P60709)
| PDB | External Database | Details |
|---|---|---|
| Ala 272 | Cys 272 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 266471.6 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 2090.9 | |
| All* | Total formula weight | 268562.6 |
