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2ZVO
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BU of 2zvo by Molmil
NEMO CoZi domain in complex with diubiquitin in C2 space group
Descriptor: NF-kappa-B essential modulator, UBC protein
Authors:Rahighi, S, Ikeda, F, Kawasaki, M, Akutsu, M, Suzuki, N, Kato, R, Kensche, T, Uejima, T, Bloor, S, Komander, D, Randow, F, Wakatsuki, S, Dikic, I.
Deposit date:2008-11-12
Release date:2009-03-24
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation
Cell(Cambridge,Mass.), 136, 2009
3DBH
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BU of 3dbh by Molmil
Structural Dissection of a Gating Mechanism Preventing Misactivation of Ubiquitin by NEDD8's E1 (APPBP1-UBA3Arg190Ala-NEDD8Ala72Arg)
Descriptor: NEDD8, NEDD8-activating enzyme E1 catalytic subunit, NEDD8-activating enzyme E1 regulatory subunit, ...
Authors:Souphron, J, Schulman, B.A.
Deposit date:2008-05-31
Release date:2008-08-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural dissection of a gating mechanism preventing misactivation of ubiquitin by NEDD8's E1.
Biochemistry, 47, 2008
3C0R
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BU of 3c0r by Molmil
Structure of Ovarian Tumor (OTU) domain in complex with Ubiquitin
Descriptor: 3-AMINOPROPANE, Ubiquitin, Ubiquitin thioesterase OTU1
Authors:Messick, T.E, Marmorstein, R.
Deposit date:2008-01-21
Release date:2008-02-19
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.315 Å)
Cite:Structural basis for ubiquitin recognition by the Otu1 ovarian tumor domain protein
J.Biol.Chem., 283, 2008
2Z59
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BU of 2z59 by Molmil
Complex Structures of Mouse Rpn13 (22-130aa) and ubiquitin
Descriptor: Protein ADRM1, Ubiquitin
Authors:Chen, X, Schreiner, P, Groll, M, Walters, K.J.
Deposit date:2007-07-01
Release date:2008-05-20
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Ubiquitin docking at the proteasome through a novel pleckstrin-homology domain interaction.
Nature, 453, 2008
3BY4
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BU of 3by4 by Molmil
Structure of Ovarian Tumor (OTU) domain in complex with Ubiquitin
Descriptor: 3-AMINOPROPANE, Ubiquitin, Ubiquitin thioesterase OTU1
Authors:Messick, T.E, Marmorstein, R.
Deposit date:2008-01-15
Release date:2008-02-19
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural basis for ubiquitin recognition by the Otu1 ovarian tumor domain protein
J.Biol.Chem., 283, 2008
3DBR
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BU of 3dbr by Molmil
Structural Dissection of a Gating Mechanism Preventing Misactivation of Ubiquitin by NEDD8's E1 (APPBP1-UBA3Arg190Gln-NEDD8Ala72Arg)
Descriptor: NEDD8, NEDD8-activating enzyme E1 catalytic subunit, NEDD8-activating enzyme E1 regulatory subunit, ...
Authors:Souphron, J, Schulman, B.A.
Deposit date:2008-06-02
Release date:2008-08-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structural dissection of a gating mechanism preventing misactivation of ubiquitin by NEDD8's E1.
Biochemistry, 47, 2008
3A1Q
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BU of 3a1q by Molmil
Crystal structure of the mouse RAP80 UIMs in complex with Lys63-linked di-ubiquitin
Descriptor: Ubiquitin, Ubiquitin interaction motif-containing protein 1
Authors:Sato, Y, Yoshikawa, A, Mimura, H, Yamashita, M, Yamagata, A, Fukai, S.
Deposit date:2009-04-21
Release date:2009-07-21
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for specific recognition of Lys 63-linked polyubiquitin chains by tandem UIMs of RAP80
Embo J., 28, 2009
3AI5
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BU of 3ai5 by Molmil
Crystal structure of yeast enhanced green fluorescent protein-ubiquitin fusion protein
Descriptor: 1,2-ETHANEDIOL, yeast enhanced green fluorescent protein,Ubiquitin
Authors:Suzuki, N, Wakatsuki, S, Kawasaki, M.
Deposit date:2010-05-10
Release date:2010-09-29
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystallization of small proteins assisted by green fluorescent protein
Acta Crystallogr.,Sect.D, 66, 2010
4FBJ
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BU of 4fbj by Molmil
Structure of the Cif:Nedd8 complex - Photorhabdus luminescens Cycle Inhibiting Factor in complex with human Nedd8
Descriptor: CHLORIDE ION, Hypothetical protein, NEDD8
Authors:Crow, A, Banfield, M.J.
Deposit date:2012-05-23
Release date:2012-06-20
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The molecular basis of Nedd8 deamidation by the bacterial effector protein Cif
Proc.Natl.Acad.Sci.USA, 2012
4GIV
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BU of 4giv by Molmil
Crystal structure of a SMT fusion Peptidyl-prolyl cis-trans isomerase with surface mutation D44G from Burkholderia pseudomallei complexed with CJ183
Descriptor: 3-(pyridin-3-yl)propyl (2S)-1-[(3-nitrophenyl)sulfonyl]piperidine-2-carboxylate, FORMIC ACID, Ubiquitin-like protein SMT3, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2012-08-09
Release date:2012-09-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:A structural biology approach enables the development of antimicrobials targeting bacterial immunophilins.
Antimicrob.Agents Chemother., 58, 2014
4GGQ
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BU of 4ggq by Molmil
Crystal structure of a SMT fusion Peptidyl-prolyl cis-trans isomerase from Burkholderia pseudomallei complexed with CJ40
Descriptor: 3-(3,4,5-trimethoxyphenyl)propyl (2S)-1-(benzylsulfonyl)piperidine-2-carboxylate, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2012-08-07
Release date:2012-08-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:A structural biology approach enables the development of antimicrobials targeting bacterial immunophilins.
Antimicrob.Agents Chemother., 58, 2014
4FJV
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BU of 4fjv by Molmil
Crystal Structure of Human Otubain2 and Ubiquitin Complex
Descriptor: ETHANAMINE, GLYCEROL, Polyubiquitin-C, ...
Authors:Altun, M, Walter, T.S, Kramer, H.B, Iphofer, A, David, Y, Komsany, A, Ternette, N, Nicholson, B, Navon, A, Stuart, D.I, Ren, J, Kessler, B.M.
Deposit date:2012-06-12
Release date:2013-06-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.047 Å)
Cite:The human otubain2-ubiquitin structure provides insights into the cleavage specificity of poly-ubiquitin-linkages.
Plos One, 10, 2015
4HCN
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BU of 4hcn by Molmil
Crystal structure of Burkholderia pseudomallei effector protein CHBP in complex with ubiquitin
Descriptor: DI(HYDROXYETHYL)ETHER, FORMIC ACID, PHOSPHATE ION, ...
Authors:Yao, Q, Cui, J, Zhu, Y, Shao, F.
Deposit date:2012-09-30
Release date:2012-11-21
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural mechanism of ubiquitin and NEDD8 deamidation catalyzed by bacterial effectors that induce macrophage-specific apoptosis.
Proc.Natl.Acad.Sci.USA, 109, 2012
4HCP
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BU of 4hcp by Molmil
crystal structure of Burkholderia pseudomallei effector protein chbp in complex with nedd8
Descriptor: GLYCEROL, NEDD8, Putative ATP/GTP binding protein, ...
Authors:Yao, Q, Shao, F.
Deposit date:2012-10-01
Release date:2012-11-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Structural mechanism of ubiquitin and NEDD8 deamidation catalyzed by bacterial effectors that induce macrophage-specific apoptosis.
Proc.Natl.Acad.Sci.USA, 109, 2012
4FN2
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BU of 4fn2 by Molmil
Crystal structure of a SMT fusion Peptidyl-prolyl cis-trans isomerase with surface mutation D44G from Burkholderia pseudomallei complexed with CJ37
Descriptor: Ubiquitin-like protein SMT3, Peptidyl-prolyl cis-trans isomerase, ethyl (2S)-1-(benzylsulfonyl)piperidine-2-carboxylate
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2012-06-19
Release date:2012-08-01
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:A structural biology approach enables the development of antimicrobials targeting bacterial immunophilins.
Antimicrob.Agents Chemother., 58, 2014
4F8C
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BU of 4f8c by Molmil
Structure of the Cif:Nedd8 complex - Yersinia pseudotuberculosis Cycle Inhibiting Factor in complex with human Nedd8
Descriptor: 1,2-ETHANEDIOL, Cycle Inhibiting Factor, NEDD8
Authors:Crow, A, Banfield, M.
Deposit date:2012-05-17
Release date:2012-06-20
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The molecular basis of Nedd8 deamidation by the bacterial effector protein Cif
Proc.Natl.Acad.Sci.USA, 2012
4G50
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BU of 4g50 by Molmil
Crystal structure of a SMT fusion Peptidyl-prolyl cis-trans isomerase with surface mutation D44G from Burkholderia pseudomallei complexed with CJ168
Descriptor: 1,2-ETHANEDIOL, 3-(3,4,5-trimethoxyphenyl)propyl (2S)-1-(benzylsulfonyl)piperidine-2-carboxylate, FORMIC ACID, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2012-07-17
Release date:2012-08-01
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:A structural biology approach enables the development of antimicrobials targeting bacterial immunophilins.
Antimicrob.Agents Chemother., 58, 2014
4HXD
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BU of 4hxd by Molmil
Diversity of ubiquitin and ISG15 specificity amongst nairoviruses viral ovarian tumor domain proteases
Descriptor: 1.7.6 3-bromanylpropan-1-amine, Polyubiquitin-C, RNA-directed RNA polymerase L, ...
Authors:Capodagli, G.C, Pegan, S.D.
Deposit date:2012-11-09
Release date:2013-02-13
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Diversity of Ubiquitin and ISG15 Specificity among Nairoviruses' Viral Ovarian Tumor Domain Proteases.
J.Virol., 87, 2013
5C7M
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BU of 5c7m by Molmil
CRYSTAL STRUCTURE OF E3 LIGASE ITCH WITH A UB VARIANT
Descriptor: E3 ubiquitin-protein ligase Itchy homolog, Polyubiquitin-C
Authors:Walker, J.R, Hu, J, Dong, A, Wernimont, A, Zhang, W, Sidhu, S, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Tong, Y, Structural Genomics Consortium (SGC)
Deposit date:2015-06-24
Release date:2016-03-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.03 Å)
Cite:System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.
Mol.Cell, 62, 2016
5C23
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BU of 5c23 by Molmil
Parkin (S65DUblR0RBR)
Descriptor: CHLORIDE ION, E3 ubiquitin-protein ligase parkin, GLYCEROL, ...
Authors:Kumar, A, Aguirre, J.D, Condos, T.E.C, Martinez-Torres, R.J, Chaugule, V.K, Toth, R, Sundaramoorthy, R, Mercier, P, Knebel, A, Spratt, D.E, Barber, K.R, Shaw, G.S, Walden, H.
Deposit date:2015-06-15
Release date:2015-07-29
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis.
Embo J., 34, 2015
5CHV
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BU of 5chv by Molmil
Crystal structure of USP18-ISG15 complex
Descriptor: CHLORIDE ION, SULFATE ION, Ubiquitin-like protein ISG15, ...
Authors:Fritz, G, Basters, A.
Deposit date:2015-07-10
Release date:2016-09-28
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.005 Å)
Cite:Structural basis of the specificity of USP18 toward ISG15.
Nat. Struct. Mol. Biol., 24, 2017
5C1Z
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BU of 5c1z by Molmil
Parkin (UblR0RBR)
Descriptor: CHLORIDE ION, E3 ubiquitin-protein ligase parkin, GLYCEROL, ...
Authors:kumar, A, Aguirre, J.D, Condos, T.E.C, Martinez-Torres, R.J, Chaugule, V.K, Toth, R, Sundaramoorthy, R, Mercier, P, Knebel, A, Spratt, D.E, Barber, K.R, Shaw, G.S, Walden, H.
Deposit date:2015-06-15
Release date:2015-07-29
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis.
Embo J., 34, 2015
5C7J
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BU of 5c7j by Molmil
CRYSTAL STRUCTURE OF NEDD4 WITH A UB VARIANT
Descriptor: E3 ubiquitin-protein ligase NEDD4, Polyubiquitin-C
Authors:Walker, J.R, Hu, J, Dong, A, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Tong, Y, Structural Genomics Consortium (SGC)
Deposit date:2015-06-24
Release date:2016-03-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.
Mol.Cell, 62, 2016
5CVM
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BU of 5cvm by Molmil
USP46~ubiquitin BEA covalent complex
Descriptor: Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 46, ZINC ION
Authors:Harris, S.F, Yin, J.
Deposit date:2015-07-27
Release date:2015-10-07
Last modified:2015-11-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Insights into WD-Repeat 48 Activation of Ubiquitin-Specific Protease 46.
Structure, 23, 2015
5CRA
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BU of 5cra by Molmil
Structure of the SdeA DUB Domain
Descriptor: METHYL 4-AMINOBUTANOATE, Polyubiquitin-B, SULFATE ION, ...
Authors:Sheedlo, M.J, Qiu, J, Luo, Z.Q, Das, C.
Deposit date:2015-07-22
Release date:2015-11-25
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Structural basis of substrate recognition by a bacterial deubiquitinase important for dynamics of phagosome ubiquitination.
Proc.Natl.Acad.Sci.USA, 112, 2015

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