3PSE

Structure of a viral OTU domain protease bound to interferon-stimulated gene 15 (ISG15)

Summary for 3PSE

• Entry DOI: 10.2210/pdb3pse/pdb
• Related: 3PT2
• Descriptor: RNA polymerase, Ubiquitin-like protein ISG15, 1.7.6 3-bromanylpropan-1-amine, ... (5 entities in total)
• Functional Keywords: viral deubiquitinase, 3-aminopropane, intein-mediated ligation, crimean-congo hemorrhagic fever virus, hydrolase-protein binding complex, hydrolase/protein binding
• Biological source: Crimean-Congo hemorrhagic fever virus; More
• Cellular location: Cytoplasm: P05161
• Total number of polymer chains: 2
• Total formula weight: 36828.52

Authors

Bacik, J.P.,James, T.W.,Frias-Staheli, N.,Garcia-Sastre, A.,Mark, B.L. (deposition date: 2010-12-01, release date: 2011-01-19, Last modification date: 2023-09-20)

• Primary citation: James, T.W.,Frias-Staheli, N.,Bacik, J.P.,Levingston Macleod, J.M.,Khajehpour, M.,Garcia-Sastre, A.,Mark, B.L.; Structural basis for the removal of ubiquitin and interferon-stimulated gene 15 by a viral ovarian tumor domain-containing protease.; Proc.Natl.Acad.Sci.USA, 108:2222-2227, 2011; PubMed: 21245344; DOI: 10.1073/pnas.1013388108

Experimental method

X-RAY DIFFRACTION (2.3 Å)