3PSE
Structure of a viral OTU domain protease bound to interferon-stimulated gene 15 (ISG15)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | RNA polymerase | polymer | 171 | 19480.8 | 1 | UniProt (Q6TQF5) Pfam (PF02338) UniProt (by SIFTS) (Q6TQR6) In PDB | Crimean-Congo hemorrhagic fever virus | |
| 2 | B | Ubiquitin-like protein ISG15 | polymer | 156 | 17117.6 | 1 | UniProt (P05161) Pfam (PF00240) In PDB | Homo sapiens (human) | Interferon-induced 15 kDa protein, Interferon-induced 17 kDa protein, IP17, Ubiquitin cross-reactive protein, hUCRP |
| 3 | B | 1.7.6 3-bromanylpropan-1-amine | non-polymer | 138.0 | 1 | Chemie (4LJ) | |||
| 4 | B | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | water | water | 18.0 | 139 | Chemie (HOH) |
Sequence modifications
A: 1 - 169 (UniProt: Q6TQF5)
B: 1 - 156 (UniProt: P05161)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Pro 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 78 | Cys 78 | engineered mutation |
| Asn 83 | Ser 83 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 36598.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 230.1 | |
| All* | Total formula weight | 36828.5 |
