PDB: 72308 resultsInfo pagesStatus searchChemie searchBIRD

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6TYG	Crystal structure of MTB sigma L transcription initiation complex with 9 nt long RNA primer Descriptor: DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*AP*TP*CP*GP*AP*GP*GP*GP*TP*G)-3'), DNA (5'-D(P*GP*TP*GP*TP*CP*AP*GP*TP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Molodtsov, V, Ebright, R.H. Deposit date: 2019-08-08 Release date: 2020-03-11 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.5 Å) Cite: RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription. Proc.Natl.Acad.Sci.USA, 117, 2020
6TYE	Crystal structure of MTB sigma L transcription initiation complex with 5 nt long RNA primer Descriptor: DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*AP*TP*CP*GP*AP*GP*G)-3'), DNA (5'-D(P*GP*TP*GP*TP*CP*AP*GP*TP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Molodtsov, V, Ebright, R.H. Deposit date: 2019-08-08 Release date: 2020-03-11 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.79 Å) Cite: RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription. Proc.Natl.Acad.Sci.USA, 117, 2020
1K8W	Crystal structure of the E. coli pseudouridine synthase TruB bound to a T stem-loop RNA Descriptor: 5'-R(*GP*GP*CP*AP*AP*CP*GP*GP*UP*(FHU)P*CP*GP*AP*UP*CP*CP*CP*GP*UP*UP*GP*C)-3', SULFATE ION, tRNA Pseudouridine Synthase B Authors: Hoang, C, Ferre-D'Amare, A.R. Deposit date: 2001-10-25 Release date: 2001-12-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Cocrystal structure of a tRNA Psi55 pseudouridine synthase: nucleotide flipping by an RNA-modifying enzyme. Cell(Cambridge,Mass.), 107, 2001
1MT4	Structure of 23S ribosomal RNA hairpin 35 Descriptor: 23S ribosomal Hairpin 35 Authors: Lebars, I, Yoshizawa, S, Stenholm, A.R, Guittet, E, Douthwaite, S, Fourmy, D. Deposit date: 2002-09-20 Release date: 2003-01-14 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Structure of 23S rRNA hairpin 35 and its interaction with the tylosin-resistance methyltransferase RlmAII Embo J., 22, 2003
8FIY	Cryo-EM structure of E. coli RNA polymerase Elongation complex in the Transcription-Translation Complex (RNAP in an anti-swiveled conformation) Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Florez Ariza, A, Wee, L, Tong, A, Canari, C, Grob, P, Nogales, E, Bustamante, C. Deposit date: 2022-12-17 Release date: 2023-03-29 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (7.3 Å) Cite: A trailing ribosome speeds up RNA polymerase at the expense of transcript fidelity via force and allostery. Cell, 186, 2023
8GZR	Cryo-EM structure of the the NS5-NS3 RNA-elongation complex Descriptor: CYTIDINE-5'-DIPHOSPHATE, Genome polyprotein, MANGANESE (II) ION, ... Authors: Osawa, T, Ehara, H, Sekine, S. Deposit date: 2022-09-27 Release date: 2023-08-02 Last modified: 2023-08-23 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Structures of dengue virus RNA replicase complexes. Mol.Cell, 83, 2023
5OC5	Crystal structure of human tRNA-dihydrouridine(20) synthase dsRBD K419A-K420A mutant Descriptor: CHLORIDE ION, GLYCEROL, tRNA-dihydrouridine(20) synthase [NAD(P)+]-like Authors: Bou-nader, C, Pecqueur, L, Hamdane, D. Deposit date: 2017-06-29 Release date: 2018-12-26 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.893 Å) Cite: Molecular basis for transfer RNA recognition by the double-stranded RNA-binding domain of human dihydrouridine synthase 2. Nucleic Acids Res., 47, 2019
5OC4	Crystal structure of human tRNA-dihydrouridine(20) synthase dsRBD R361A-R362A mutant Descriptor: CACODYLATE ION, CHLORIDE ION, GLYCEROL, ... Authors: Bou-nader, C, Pecqueur, L, Hamdane, D. Deposit date: 2017-06-29 Release date: 2018-12-26 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.71 Å) Cite: Molecular basis for transfer RNA recognition by the double-stranded RNA-binding domain of human dihydrouridine synthase 2. Nucleic Acids Res., 47, 2019
1Y1V	Refined RNA Polymerase II-TFIIS complex Descriptor: DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 140 kDa polypeptide, DNA-directed RNA polymerase II 19 kDa polypeptide, ... Authors: Kettenberger, H, Armache, K.-J, Cramer, P. Deposit date: 2004-11-19 Release date: 2004-12-28 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (3.8 Å) Cite: Complete RNA polymerase II elongation complex structure and its interactions with NTP and TFIIS. Mol.Cell, 16, 2004
4PKD	U1-70k in complex with U1 snRNA stem-loops 1 and U1-A RRM in complex with stem-loop 2 Descriptor: IMIDAZOLE, MAGNESIUM ION, U1 small nuclear ribonucleoprotein A,U1 small nuclear ribonucleoprotein 70 kDa, ... Authors: Oubridge, C, Kondo, Y, van Roon, A.M, Nagai, K. Deposit date: 2014-05-14 Release date: 2014-12-31 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystal structure of human U1 snRNP, a small nuclear ribonucleoprotein particle, reveals the mechanism of 5' splice site recognition. Elife, 4, 2015
3Q2T	Crystal Structure of CFIm68 RRM/CFIm25/RNA complex Descriptor: Cleavage and polyadenylation specificity factor subunit 5, Cleavage and polyadenylation specificity factor subunit 6, RNA Authors: Yang, Q, Coseno, M, Gilmartin, G.M, Doublie, S. Deposit date: 2010-12-20 Release date: 2011-02-16 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (3.061 Å) Cite: Crystal Structure of a Human Cleavage Factor CFI(m)25/CFI(m)68/RNA Complex Provides an Insight into Poly(A) Site Recognition and RNA Looping. Structure, 19, 2011
3V11	Structure of the ternary initiation complex AIF2:GDPNP:methionylated initiator TRNA Descriptor: Initiator tRNA, MAGNESIUM ION, METHIONINE, ... Authors: Mechulam, Y, Schmitt, E. Deposit date: 2011-12-09 Release date: 2012-03-28 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (5 Å) Cite: Structure of the ternary initiation complex aIF2-GDPNP-methionylated initiator tRNA. Nat.Struct.Mol.Biol., 19, 2012
8HSG	Thermus thermophilus RNA polymerase elongation complex Descriptor: DNA (27-MER), DNA (37-MER), DNA-directed RNA polymerase subunit alpha, ... Authors: Murayama, Y, Ehara, H, Sekine, S. Deposit date: 2022-12-19 Release date: 2023-05-03 Last modified: 2024-07-03 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Structural basis of the transcription termination factor Rho engagement with transcribing RNA polymerase from Thermus thermophilus. Sci Adv, 9, 2023
8HSL	Thermus thermophilus RNA polymerase bound with an inverted Rho hexamer Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase subunit alpha, ... Authors: Murayama, Y, Ehara, H, Sekine, S. Deposit date: 2022-12-19 Release date: 2023-05-03 Last modified: 2024-07-03 Method: ELECTRON MICROSCOPY (5.8 Å) Cite: Structural basis of the transcription termination factor Rho engagement with transcribing RNA polymerase from Thermus thermophilus. Sci Adv, 9, 2023
8HSR	Thermus thermophilus Rho-engaged RNAP elongation complex Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA (31-MER), ... Authors: Murayama, Y, Ehara, H, Sekine, S. Deposit date: 2022-12-20 Release date: 2023-05-03 Method: ELECTRON MICROSCOPY (4 Å) Cite: Structural basis of the transcription termination factor Rho engagement with transcribing RNA polymerase from Thermus thermophilus. Sci Adv, 9, 2023
8FIX	Cryo-EM structure of E. coli RNA polymerase backtracked elongation complex harboring a terminal mismatch Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Florez Ariza, A, Wee, L, Tong, A, Canari, C, Grob, P, Nogales, E, Bustamante, C. Deposit date: 2022-12-17 Release date: 2023-03-29 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: A trailing ribosome speeds up RNA polymerase at the expense of transcript fidelity via force and allostery. Cell, 186, 2023
7AAV	Human pre-Bact-2 spliceosome core structure Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, D-chiro inositol hexakisphosphate, ... Authors: Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R. Deposit date: 2020-09-04 Release date: 2020-12-09 Last modified: 2020-12-30 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation. Science, 370, 2020
6NSX	Yeast Hsh155 Ligand bound to Human Tat-SF1 Motif Descriptor: CHLORIDE ION, HIV Tat-specific factor 1, Hsh155 Authors: Jenkins, J.L, Leach, J.R, Kielkopf, C.L. Deposit date: 2019-01-25 Release date: 2019-06-05 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2 Å) Cite: Cus2 enforces the first ATP-dependent step of splicing by binding to yeast SF3b1 through a UHM-ULM interaction. Rna, 25, 2019
5X6C	Crystal structure of SepRS-SepCysE from Methanocaldococcus jannaschii Descriptor: ADENOSINE-5'-TRIPHOSPHATE, O-phosphoserine--tRNA(Cys) ligase, SULFATE ION, ... Authors: Chen, M, Kato, K, Yao, M. Deposit date: 2017-02-21 Release date: 2017-12-06 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (3.101 Å) Cite: Structural basis for tRNA-dependent cysteine biosynthesis Nat Commun, 8, 2017
4PZ6	PCE1 guanylyltransferase bound to SER2/SER5 phosphorylated RNA pol II CTD Descriptor: DNA-directed RNA polymerase II subunit rpb1, GUANOSINE, mRNA-capping enzyme subunit alpha Authors: Doamekpor, S.K, Lima, C.D. Deposit date: 2014-03-28 Release date: 2014-06-25 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.406 Å) Cite: How an mRNA capping enzyme reads distinct RNA polymerase II and Spt5 CTD phosphorylation codes. Genes Dev., 28, 2014
6KQF	Thermus thermophilus initial transcription complex comprising sigma A and 5'-OH RNA of 5 nt Descriptor: DNA (5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G*)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Zhang, Y, Li, L, Ebright, R.H. Deposit date: 2019-08-17 Release date: 2020-03-11 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.45 Å) Cite: RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription. Proc.Natl.Acad.Sci.USA, 117, 2020
6NY5	Crystal structure of the PUM-HD domain of S. pombe Puf1 in complex with RNA Descriptor: MAGNESIUM ION, Pumilio domain-containing protein C56F2.08c, RNA (5'-R(P*UP*UP*AP*AP*UP*AP*AP*CP*UP*UP*AP*AP*U)-3'), ... Authors: Qiu, C, Hall, T.M.T. Deposit date: 2019-02-11 Release date: 2019-07-03 Last modified: 2020-01-15 Method: X-RAY DIFFRACTION (3.002 Å) Cite: Distinct RNA-binding modules in a single PUF protein cooperate to determine RNA specificity. Nucleic Acids Res., 47, 2019
6L74	Thermus thermophilus initial transcription complex comprising sigma A and 5'-triphosphate RNA of 2 nt Descriptor: DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Zhang, Y, Li, L, Ebright, R.H. Deposit date: 2019-10-31 Release date: 2020-03-11 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (3.12 Å) Cite: RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription. Proc.Natl.Acad.Sci.USA, 117, 2020
8HSH	Thermus thermophilus RNA polymerase coreenzyme Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Murayama, Y, Ehara, H, Sekine, S. Deposit date: 2022-12-19 Release date: 2023-05-03 Last modified: 2024-07-03 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structural basis of the transcription termination factor Rho engagement with transcribing RNA polymerase from Thermus thermophilus. Sci Adv, 9, 2023
354D	Structure of loop E FROM E. coli 5S RRNA Descriptor: MAGNESIUM ION, RNA (5'-R(*CP*CP*GP*AP*UP*GP*GP*UP*AP*GP*UP*G)-3'), RNA-DNA (5'-R(*GP*CP*GP*AP*GP*AP*GP*UP*AP*)-D(*DGP(S)*)-R(*GP*C)-3') Authors: Correll, C.C, Freeborn, B, Moore, P.B, Steitz, T.A. Deposit date: 1997-10-01 Release date: 1997-11-26 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Metals, motifs, and recognition in the crystal structure of a 5S rRNA domain. Cell(Cambridge,Mass.), 91, 1997

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