8FIX
Cryo-EM structure of E. coli RNA polymerase backtracked elongation complex harboring a terminal mismatch
Summary for 8FIX
| Entry DOI | 10.2210/pdb8fix/pdb |
| EMDB information | 29212 |
| Descriptor | Non-template DNA, Template DNA, DNA-directed RNA polymerase subunit alpha, ... (9 entities in total) |
| Functional Keywords | rna polymerase, ribosome, coupling, transcription |
| Biological source | Escherichia coli K-12 More |
| Total number of polymer chains | 8 |
| Total formula weight | 404867.38 |
| Authors | Florez Ariza, A.,Wee, L.,Tong, A.,Canari, C.,Grob, P.,Nogales, E.,Bustamante, C. (deposition date: 2022-12-17, release date: 2023-03-29) |
| Primary citation | Wee, L.M.,Tong, A.B.,Florez Ariza, A.J.,Canari-Chumpitaz, C.,Grob, P.,Nogales, E.,Bustamante, C.J. A trailing ribosome speeds up RNA polymerase at the expense of transcript fidelity via force and allostery. Cell, 186:1244-1262.e34, 2023 Cited by PubMed: 36931247DOI: 10.1016/j.cell.2023.02.008 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.9 Å) |
Structure validation
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