4PKD
U1-70k in complex with U1 snRNA stem-loops 1 and U1-A RRM in complex with stem-loop 2
Summary for 4PKD
Entry DOI | 10.2210/pdb4pkd/pdb |
Related | 1URN 3CW1 3PGW |
Descriptor | U1 snRNA stem-loops 1 and 2 (55-MER), U1 small nuclear ribonucleoprotein A,U1 small nuclear ribonucleoprotein 70 kDa, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | u1-70k, u1 snrnp, pre-mrna splicing, spliceosome, gene regulation |
Biological source | Sus scrofa (Pig) More |
Cellular location | Nucleus: P08621 |
Total number of polymer chains | 2 |
Total formula weight | 50112.00 |
Authors | Oubridge, C.,Kondo, Y.,van Roon, A.M.,Nagai, K. (deposition date: 2014-05-14, release date: 2014-12-31, Last modification date: 2023-12-20) |
Primary citation | Kondo, Y.,Oubridge, C.,van Roon, A.M.,Nagai, K. Crystal structure of human U1 snRNP, a small nuclear ribonucleoprotein particle, reveals the mechanism of 5' splice site recognition. Elife, 4:-, 2015 Cited by PubMed: 25555158DOI: 10.7554/eLife.04986 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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