5OC5

Crystal structure of human tRNA-dihydrouridine(20) synthase dsRBD K419A-K420A mutant

Summary for 5OC5

Entry DOI	10.2210/pdb5oc5/pdb
Descriptor	tRNA-dihydrouridine(20) synthase [NAD(P)+]-like, GLYCEROL, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	double-stranded rna-binding domain, rna binding protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	13959.68
Authors	Bou-nader, C.,Pecqueur, L.,Hamdane, D. (deposition date: 2017-06-29, release date: 2018-12-26, Last modification date: 2024-01-17)
Primary citation	Bou-Nader, C.,Barraud, P.,Pecqueur, L.,Perez, J.,Velours, C.,Shepard, W.,Fontecave, M.,Tisne, C.,Hamdane, D. Molecular basis for transfer RNA recognition by the double-stranded RNA-binding domain of human dihydrouridine synthase 2. Nucleic Acids Res., 47:3117-3126, 2019 Cited by PubMed: 30605527 DOI: 10.1093/nar/gky1302 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.893 Å)

Structure validation