5OC5
Crystal structure of human tRNA-dihydrouridine(20) synthase dsRBD K419A-K420A mutant
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000049 | molecular_function | tRNA binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 501 |
| Chain | Residue |
| A | THR390 |
| A | GOL503 |
| A | HOH605 |
| A | HOH633 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 502 |
| Chain | Residue |
| A | ARG397 |
| A | LYS417 |
| A | HOH637 |
| A | HOH654 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 503 |
| Chain | Residue |
| A | GOL501 |
| A | HOH618 |
| A | GLN392 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 504 |
| Chain | Residue |
| A | ARG361 |
| A | TRP377 |
| A | ARG380 |
| A | SER418 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 505 |
| Chain | Residue |
| A | HOH606 |
| A | HOH641 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 67 |
| Details | Domain: {"description":"DRBM","evidences":[{"source":"PubMed","id":"26429968","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Region: {"description":"Interaction with tRNA","evidences":[{"source":"PubMed","id":"30605527","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38680565","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
