8FIY

Cryo-EM structure of E. coli RNA polymerase Elongation complex in the Transcription-Translation Complex (RNAP in an anti-swiveled conformation)

Summary for 8FIY

Entry DOI	10.2210/pdb8fiy/pdb
EMDB information	29213
Descriptor	DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... (8 entities in total)
Functional Keywords	rna polymerase, ribosome, coupling, transcription, transcription-dna-rna complex, transcription/dna/rna
Biological source	Escherichia coli K-12 More
Total number of polymer chains	7
Total formula weight	393971.48
Authors	Florez Ariza, A.,Wee, L.,Tong, A.,Canari, C.,Grob, P.,Nogales, E.,Bustamante, C. (deposition date: 2022-12-17, release date: 2023-03-29)
Primary citation	Wee, L.M.,Tong, A.B.,Florez Ariza, A.J.,Canari-Chumpitaz, C.,Grob, P.,Nogales, E.,Bustamante, C.J. A trailing ribosome speeds up RNA polymerase at the expense of transcript fidelity via force and allostery. Cell, 186:1244-1262.e34, 2023 Cited by PubMed: 36931247 DOI: 10.1016/j.cell.2023.02.008 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (7.3 Å)

Structure validation