3V96
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![BU of 3v96 by Molmil](/molmil-images/mine/3v96) | Complex of matrix metalloproteinase-10 catalytic domain (MMP-10cd) with tissue inhibitor of metalloproteinases-1 (TIMP-1) | Descriptor: | CALCIUM ION, Metalloproteinase inhibitor 1, PHOSPHATE ION, ... | Authors: | Batra, J, Soares, A.S, Radisky, E.S. | Deposit date: | 2011-12-23 | Release date: | 2012-03-28 | Last modified: | 2012-07-25 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Matrix metalloproteinase-10 (MMP-10) interaction with tissue inhibitors of metalloproteinases TIMP-1 and TIMP-2: binding studies and crystal structure. J.Biol.Chem., 287, 2012
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1LMJ
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![BU of 1lmj by Molmil](/molmil-images/mine/1lmj) | NMR Study of the Fibrillin-1 cbEGF12-13 Pair of Ca2+ Binding Epidermal Growth Factor-like Domains | Descriptor: | CALCIUM ION, fibrillin 1 | Authors: | Smallridge, R.S, Whiteman, P, Werner, J.M, Campbell, I.D, Handford, P.A, Downing, A.K. | Deposit date: | 2002-05-02 | Release date: | 2003-04-29 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Solution Structure and Dynamics of a Calcium Binding Epidermal Growth
Factor-like Domain Pair from the Neonatal Region of Human Fibrillin-1. J.Biol.Chem., 278, 2003
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8FPT
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![BU of 8fpt by Molmil](/molmil-images/mine/8fpt) | STRUCTURE OF ALPHA-SYNUCLEIN FIBRILS DERIVED FROM HUMAN LEWY BODY DEMENTIA TISSUE | Descriptor: | Alpha-synuclein | Authors: | Barclay, A.M, Dhavale, D.D, Borcik, C.G, Rau, M.J, Basore, K, Milchberg, M.H, Warmuth, O.A, Kotzbauer, P.T, Rienstra, C.M, Schwieters, C.D. | Deposit date: | 2023-01-05 | Release date: | 2023-02-22 | Last modified: | 2024-05-15 | Method: | SOLID-STATE NMR | Cite: | Structure of alpha-synuclein fibrils derived from human Lewy body dementia tissue. Biorxiv, 2023
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3T06
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![BU of 3t06 by Molmil](/molmil-images/mine/3t06) | |
1X86
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![BU of 1x86 by Molmil](/molmil-images/mine/1x86) | |
1LB1
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![BU of 1lb1 by Molmil](/molmil-images/mine/1lb1) | Crystal Structure of the Dbl and Pleckstrin homology domains of Dbs in complex with RhoA | Descriptor: | Guanine nucleotide exchange factor DBS, Transforming protein RhoA | Authors: | Snyder, J.T, Worthylake, D.K, Rossman, K.L, Betts, L, Pruitt, W.M, Siderovski, D.P, Der, C.J, Sondek, J. | Deposit date: | 2002-04-01 | Release date: | 2002-05-29 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.81 Å) | Cite: | Structural basis for the selective activation of Rho GTPases by Dbl exchange factors. Nat.Struct.Biol., 9, 2002
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6URQ
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![BU of 6urq by Molmil](/molmil-images/mine/6urq) | Complex structure of human poly-ADP-ribosyltransferase TNKS1 ARC2-ARC3 and P antigen family member 4 (PAGE4) | Descriptor: | GLYCEROL, P antigen family member 4, Poly [ADP-ribose] polymerase tankyrase-1, ... | Authors: | Zheng, Y, Koirala, S, Miller, D, Potts, P.R. | Deposit date: | 2019-10-24 | Release date: | 2020-07-29 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Tissue-Specific Regulation of the Wnt/ beta-Catenin Pathway by PAGE4 Inhibition of Tankyrase. Cell Rep, 32, 2020
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6BOF
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![BU of 6bof by Molmil](/molmil-images/mine/6bof) | |
3BFO
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![BU of 3bfo by Molmil](/molmil-images/mine/3bfo) | Crystal structure of Ig-like C2-type 2 domain of the human Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | Descriptor: | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Isoform 2) | Authors: | Walker, J.R, Akutsu, M, Littler, D.R, Li, Y, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2007-11-22 | Release date: | 2007-12-11 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Structure of the Ig-like C2-type 2 domain of the human Mucosa-associated lymphoid tissue lymphoma translocation protein 1. To be Published
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5ZV2
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![BU of 5zv2 by Molmil](/molmil-images/mine/5zv2) | FGFR-1 in complex with ligand lenvatinib | Descriptor: | 4-{3-chloro-4-[(cyclopropylcarbamoyl)amino]phenoxy}-7-methoxyquinoline-6-carboxamide, Fibroblast growth factor receptor 1 | Authors: | Matsuki, M, Hoshi, T, Yamamoto, Y, Ikemori-Kawada, M, Minoshima, Y, Funahashi, Y, Matsui, J. | Deposit date: | 2018-05-09 | Release date: | 2018-07-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.86 Å) | Cite: | Lenvatinib inhibits angiogenesis and tumor fibroblast growth factor signaling pathways in human hepatocellular carcinoma models. Cancer Med, 7, 2018
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1KR7
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![BU of 1kr7 by Molmil](/molmil-images/mine/1kr7) | Crystal structure of the nerve tissue mini-hemoglobin from the nemertean worm Cerebratulus lacteus | Descriptor: | ACETATE ION, Neural globin, OXYGEN MOLECULE, ... | Authors: | Pesce, A, Nardini, M, Dewilde, S, Geuens, E, Yamauchi, k, Ascenzi, P, Riggs, A.F, Moens, L, Bolognesi, M. | Deposit date: | 2002-01-09 | Release date: | 2002-05-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | The 109 residue nerve tissue minihemoglobin from Cerebratulus lacteus highlights striking structural plasticity of the alpha-helical globin fold Structure, 10, 2002
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4Z2X
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![BU of 4z2x by Molmil](/molmil-images/mine/4z2x) | |
1F9Q
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![BU of 1f9q by Molmil](/molmil-images/mine/1f9q) | CRYSTAL STRUCTURE OF PLATELET FACTOR 4 | Descriptor: | PLATELET FACTOR 4 | Authors: | Yang, J, Doyle, M, Faulk, T, Visentin, G, Aster, R, Edwards, B. | Deposit date: | 2000-07-11 | Release date: | 2003-08-26 | Last modified: | 2017-10-04 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure Comparison of Two Platelet Factor 4 Mutants with the Wild-Type Reveals the Epitopes for the Heparin-Induced Thrombocytopenia Antibodies To be Published
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6SEO
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![BU of 6seo by Molmil](/molmil-images/mine/6seo) | TEAD4 bound to a FAM181B peptide | Descriptor: | Protein FAM181B, Transcriptional enhancer factor TEF-3 | Authors: | Scheufler, C, Villard, F. | Deposit date: | 2019-07-30 | Release date: | 2019-11-20 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Identification of FAM181A and FAM181B as new interactors with the TEAD transcription factors. Protein Sci., 29, 2020
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6SEN
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![BU of 6sen by Molmil](/molmil-images/mine/6sen) | TEAD4 bound to a FAM181A peptide | Descriptor: | Protein FAM181A, SULFATE ION, Transcriptional enhancer factor TEF-3 | Authors: | Scheufler, C, Villard, F. | Deposit date: | 2019-07-30 | Release date: | 2019-11-20 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Identification of FAM181A and FAM181B as new interactors with the TEAD transcription factors. Protein Sci., 29, 2020
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5O9K
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![BU of 5o9k by Molmil](/molmil-images/mine/5o9k) | Crystal structure of Murine Histmaine-Releasing Factor (HRF/TCTP) | Descriptor: | GLYCEROL, Translationally-controlled tumor protein | Authors: | Dore, K.A, Kashiwakura, J, McDonnell, J.M, Gould, H.J, Kawakami, T, Sutton, B.J, Davies, A.M. | Deposit date: | 2017-06-19 | Release date: | 2017-12-20 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (4.014 Å) | Cite: | Crystal structures of murine and human Histamine-Releasing Factor (HRF/TCTP) and a model for HRF dimerisation in mast cell activation. Mol. Immunol., 93, 2017
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1C28
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![BU of 1c28 by Molmil](/molmil-images/mine/1c28) | |
4JGW
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![BU of 4jgw by Molmil](/molmil-images/mine/4jgw) | |
4EFV
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![BU of 4efv by Molmil](/molmil-images/mine/4efv) | Crystal structure of OIF from Llama seminal plasma | Descriptor: | CHLORIDE ION, Ovulation-inducing factor (OIF), PHOSPHATE ION | Authors: | Van Straaten, K.E, Leduc, Y.A, Ratto, M.H, Valderrama, X.P, Delbaere, T.J, Pierson, R.A, Adams, G.P. | Deposit date: | 2012-03-30 | Release date: | 2012-08-22 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | The nerve of ovulation-inducing factor in semen. Proc.Natl.Acad.Sci.USA, 109, 2012
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5CP9
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![BU of 5cp9 by Molmil](/molmil-images/mine/5cp9) | The structure of the NK1 fragment of HGF/SF complexed with MB605 | Descriptor: | 1,2-ETHANEDIOL, 3-(furan-2-yl)propanoic acid, Hepatocyte growth factor | Authors: | Sigurdardottir, A.G, Winter, A, Sobkowicz, A, Fragai, M, Chirgadze, D.Y, Ascher, D.B, Blundell, T.L, Gherardi, E. | Deposit date: | 2015-07-21 | Release date: | 2015-08-12 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Exploring the chemical space of the lysine-binding pocket of the first kringle domain of hepatocyte growth factor/scatter factor (HGF/SF) yields a new class of inhibitors of HGF/SF-MET binding. Chem Sci, 6, 2015
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5COE
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![BU of 5coe by Molmil](/molmil-images/mine/5coe) | The structure of the NK1 fragment of HGF/SF complexed with HEPES | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Hepatocyte growth factor | Authors: | Sigurdardottir, A.G, Winter, A, Sobkowicz, A, Fragai, M, Ascher, D.B, Chirgadze, D.Y, Blundell, T.L, Gherardi, E. | Deposit date: | 2015-07-20 | Release date: | 2015-08-12 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Exploring the chemical space of the lysine-binding pocket of the first kringle domain of hepatocyte growth factor/scatter factor (HGF/SF) yields a new class of inhibitors of HGF/SF-MET binding. Chem Sci, 6, 2015
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5CSQ
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![BU of 5csq by Molmil](/molmil-images/mine/5csq) | The structure of the NK1 fragment of HGF/SF complexed with MOPS | Descriptor: | 3[N-MORPHOLINO]PROPANE SULFONIC ACID, Hepatocyte growth factor | Authors: | Sigurdardottir, A.G, Winter, A, Sobkowicz, A, Fragai, M, Chirgadze, D.Y, Ascher, D.B, Blundell, T.L, Gherardi, E. | Deposit date: | 2015-07-23 | Release date: | 2015-08-12 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Exploring the chemical space of the lysine-binding pocket of the first kringle domain of hepatocyte growth factor/scatter factor (HGF/SF) yields a new class of inhibitors of HGF/SF-MET binding. Chem Sci, 6, 2015
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5CS9
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![BU of 5cs9 by Molmil](/molmil-images/mine/5cs9) | The structure of the NK1 fragment of HGF/SF complexed with MES | Descriptor: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Hepatocyte growth factor | Authors: | Sigurdardottir, A.G, Winter, A, Sobkowicz, A, Fragai, M, Chirgadze, D.Y, Ascher, D.B, Blundell, T.L, Gherardi, E. | Deposit date: | 2015-07-23 | Release date: | 2015-08-12 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Exploring the chemical space of the lysine-binding pocket of the first kringle domain of hepatocyte growth factor/scatter factor (HGF/SF) yields a new class of inhibitors of HGF/SF-MET binding. Chem Sci, 6, 2015
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5CT1
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![BU of 5ct1 by Molmil](/molmil-images/mine/5ct1) | The structure of the NK1 fragment of HGF/SF complexed with CHES | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Hepatocyte growth factor | Authors: | Sigurdardottir, A.G, Winter, A, Sobkowicz, A, Fragai, M, Chirgadze, D.Y, Ascher, D.B, Blundell, T.L, Gherardi, E. | Deposit date: | 2015-07-23 | Release date: | 2015-08-12 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Exploring the chemical space of the lysine-binding pocket of the first kringle domain of hepatocyte growth factor/scatter factor (HGF/SF) yields a new class of inhibitors of HGF/SF-MET binding. Chem Sci, 6, 2015
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5CS1
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![BU of 5cs1 by Molmil](/molmil-images/mine/5cs1) | The structure of the NK1 fragment of HGF/SF | Descriptor: | Hepatocyte growth factor | Authors: | Sigurdardottir, A.G, Winter, A, Sobkowicz, A, Fragai, M, Chirgadze, D.Y, Ascher, D.B, Blundell, T.L, Gherardi, E. | Deposit date: | 2015-07-23 | Release date: | 2015-08-12 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Exploring the chemical space of the lysine-binding pocket of the first kringle domain of hepatocyte growth factor/scatter factor (HGF/SF) yields a new class of inhibitors of HGF/SF-MET binding. Chem Sci, 6, 2015
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