3V96
Complex of matrix metalloproteinase-10 catalytic domain (MMP-10cd) with tissue inhibitor of metalloproteinases-1 (TIMP-1)
Summary for 3V96
Entry DOI | 10.2210/pdb3v96/pdb |
Descriptor | Metalloproteinase inhibitor 1, Stromelysin-2, PHOSPHATE ION, ... (6 entities in total) |
Functional Keywords | metzincin, ob-fold, metalloproteinase, protease inhibitor, hydrolase inhibitor-hydrolase complex, hydrolase inhibitor/hydrolase |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P01033 Secreted, extracellular space, extracellular matrix (Probable): P09238 |
Total number of polymer chains | 2 |
Total formula weight | 39701.38 |
Authors | Batra, J.,Soares, A.S.,Radisky, E.S. (deposition date: 2011-12-23, release date: 2012-03-28, Last modification date: 2012-07-25) |
Primary citation | Batra, J.,Robinson, J.,Soares, A.S.,Fields, A.P.,Radisky, D.C.,Radisky, E.S. Matrix metalloproteinase-10 (MMP-10) interaction with tissue inhibitors of metalloproteinases TIMP-1 and TIMP-2: binding studies and crystal structure. J.Biol.Chem., 287:15935-15946, 2012 Cited by PubMed: 22427646DOI: 10.1074/jbc.M112.341156 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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