3V96
Complex of matrix metalloproteinase-10 catalytic domain (MMP-10cd) with tissue inhibitor of metalloproteinases-1 (TIMP-1)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Metalloproteinase inhibitor 1 | polymer | 184 | 20689.8 | 1 | UniProt (P01033) Pfam (PF00965) | Homo sapiens (human) | Erythroid-potentiating activity, EPA, Fibroblast collagenase inhibitor, Collagenase inhibitor, Tissue inhibitor of metalloproteinases 1, TIMP-1 |
| 2 | B (B) | Stromelysin-2 | polymer | 165 | 18570.6 | 1 | UniProt (P09238) Pfam (PF00413) | Homo sapiens (human) | SL-2, Matrix metalloproteinase-10, MMP-10, Transin-2 |
| 3 | C, D (A) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 4 | E, F (B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 5 | G, H, I (B) | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
| 6 | J, K (A, B) | water | water | 18.0 | 188 | Chemie (HOH) |
Sequence modifications
A: 1 - 184 (UniProt: P01033)
| PDB | External Database | Details |
|---|---|---|
| Ala 30 | Asn 53 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 39260.4 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 441.0 | |
| All* | Total formula weight | 39701.4 |
