8FPT
STRUCTURE OF ALPHA-SYNUCLEIN FIBRILS DERIVED FROM HUMAN LEWY BODY DEMENTIA TISSUE
Summary for 8FPT
Entry DOI | 10.2210/pdb8fpt/pdb |
NMR Information | BMRB: 31068 |
Descriptor | Alpha-synuclein (1 entity in total) |
Functional Keywords | protein fibril, amyloid, lewy body dementia, polymorphism, parkinson, structural protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 10 |
Total formula weight | 144761.08 |
Authors | Barclay, A.M.,Dhavale, D.D.,Borcik, C.G.,Rau, M.J.,Basore, K.,Milchberg, M.H.,Warmuth, O.A.,Kotzbauer, P.T.,Rienstra, C.M.,Schwieters, C.D. (deposition date: 2023-01-05, release date: 2023-02-22, Last modification date: 2024-05-15) |
Primary citation | Dhavale, D.D.,Barclay, A.M.,Borcik, C.G.,Basore, K.,Gordon, I.R.,Liu, J.,Milchberg, M.H.,Oa Shea, J.,Rau, M.J.,Smith, Z.,Sen, S.,Summers, B.,Smith, J.,Warmuth, O.A.,Chen, Q.,Fitzpatrick, J.A.J.,Schwieters, C.D.,Tajkhorshid, E.,Rienstra, C.M.,Kotzbauer, P.T. Structure of alpha-synuclein fibrils derived from human Lewy body dementia tissue. Biorxiv, 2023 Cited by PubMed: 36711931DOI: 10.1101/2023.01.09.523303 PDB entries with the same primary citation |
Experimental method | SOLID-STATE NMR |
Structure validation
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