8FPT

STRUCTURE OF ALPHA-SYNUCLEIN FIBRILS DERIVED FROM HUMAN LEWY BODY DEMENTIA TISSUE

Summary for 8FPT

• Entry DOI: 10.2210/pdb8fpt/pdb
• NMR Information: BMRB: 31068
• Descriptor: Alpha-synuclein (1 entity in total)
• Functional Keywords: protein fibril, amyloid, lewy body dementia, polymorphism, parkinson, structural protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 10
• Total formula weight: 144761.08

Authors

Barclay, A.M.,Dhavale, D.D.,Borcik, C.G.,Rau, M.J.,Basore, K.,Milchberg, M.H.,Warmuth, O.A.,Kotzbauer, P.T.,Rienstra, C.M.,Schwieters, C.D. (deposition date: 2023-01-05, release date: 2023-02-22, Last modification date: 2024-05-15)

• Primary citation: Dhavale, D.D.,Barclay, A.M.,Borcik, C.G.,Basore, K.,Gordon, I.R.,Liu, J.,Milchberg, M.H.,Oa Shea, J.,Rau, M.J.,Smith, Z.,Sen, S.,Summers, B.,Smith, J.,Warmuth, O.A.,Chen, Q.,Fitzpatrick, J.A.J.,Schwieters, C.D.,Tajkhorshid, E.,Rienstra, C.M.,Kotzbauer, P.T.; Structure of alpha-synuclein fibrils derived from human Lewy body dementia tissue.; Biorxiv, 2023; PubMed: 36711931; DOI: 10.1101/2023.01.09.523303

Experimental method

SOLID-STATE NMR