5LBV
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![BU of 5lbv by Molmil](/molmil-images/mine/5lbv) | Structural basis of zika and dengue virus potent antibody cross-neutralization | Descriptor: | SODIUM ION, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, envelope protein E | Authors: | Barba-Spaeth, G. | Deposit date: | 2016-06-17 | Release date: | 2016-07-06 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis of potent Zika-dengue virus antibody cross-neutralization. Nature, 536, 2016
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6PLK
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![BU of 6plk by Molmil](/molmil-images/mine/6plk) | |
6LD3
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![BU of 6ld3 by Molmil](/molmil-images/mine/6ld3) | Zika NS5 polymerase domain | Descriptor: | 2,4-dimethoxy-5-thiophen-2-yl-benzoic acid, RNA-directed RNA polymerase NS5, ZINC ION, ... | Authors: | El Sahili, A, Lescar, J. | Deposit date: | 2019-11-20 | Release date: | 2020-08-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Non-nucleoside Inhibitors of Zika Virus RNA-Dependent RNA Polymerase. J.Virol., 94, 2020
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5LBS
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![BU of 5lbs by Molmil](/molmil-images/mine/5lbs) | structural basis of Zika and Dengue virus potent antibody cross-neutralization | Descriptor: | 1,2-ETHANEDIOL, BROADLY NEUTRALIZING HUMAN ANTIBODY EDE1 C8, SULFATE ION, ... | Authors: | Vaney, M.C, Rouvinski, A, Barba-Spaeth, G, Rey, F.A. | Deposit date: | 2016-06-17 | Release date: | 2016-07-06 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Structural basis of potent Zika-dengue virus antibody cross-neutralization. Nature, 536, 2016
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5GP1
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![BU of 5gp1 by Molmil](/molmil-images/mine/5gp1) | Crystal structure of ZIKV NS5 Methyltransferase in complex with GTP and SAH | Descriptor: | NICKEL (II) ION, P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE, RNA-directed RNA polymerase NS5, ... | Authors: | Zhang, C, Jin, T. | Deposit date: | 2016-07-30 | Release date: | 2016-12-07 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (2.444 Å) | Cite: | Structure of the NS5 methyltransferase from Zika virus and implications in inhibitor design Biochem. Biophys. Res. Commun., 492, 2017
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7YW8
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![BU of 7yw8 by Molmil](/molmil-images/mine/7yw8) | |
6UM3
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![BU of 6um3 by Molmil](/molmil-images/mine/6um3) | |
7BSD
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![BU of 7bsd by Molmil](/molmil-images/mine/7bsd) | |
7YW7
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![BU of 7yw7 by Molmil](/molmil-images/mine/7yw7) | |
5LCV
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![BU of 5lcv by Molmil](/molmil-images/mine/5lcv) | |
8EE8
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![BU of 8ee8 by Molmil](/molmil-images/mine/8ee8) | |
8EEE
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![BU of 8eee by Molmil](/molmil-images/mine/8eee) | |
7BQ5
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![BU of 7bq5 by Molmil](/molmil-images/mine/7bq5) | ZIKV sE bound to mAb Z6 | Descriptor: | Z6 Light Chain, Z6 heavy chain, envelope protein | Authors: | Dai, L, Qi, J, Gao, G.F. | Deposit date: | 2020-03-24 | Release date: | 2021-03-24 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.99 Å) | Cite: | Protective Zika vaccines engineered to eliminate enhancement of dengue infection via immunodominance switch. Nat.Immunol., 22, 2021
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7A3U
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![BU of 7a3u by Molmil](/molmil-images/mine/7a3u) | Crystal structure of Zika virus envelope glycoprotein in complex with the divalent F(ab')2 fragment of the broadly neutralizing human antibody EDE1 C10 | Descriptor: | EDE1 C10 antibody divalent F(ab')2 fragment, EDE1 C10 divalent F(ab')2 fragment, Envelope protein | Authors: | Sharma, A, Vaney, M.C, Guardado-Calvo, P, Duquerroy, S, Rouvinski, A, Rey, F.A. | Deposit date: | 2020-08-18 | Release date: | 2021-12-08 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The epitope arrangement on flavivirus particles contributes to Mab C10's extraordinary neutralization breadth across Zika and dengue viruses. Cell, 184, 2021
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7BPK
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![BU of 7bpk by Molmil](/molmil-images/mine/7bpk) | Zika virus envelope protein mutant bound to mAb | Descriptor: | Envelope protein, IG c307_light_IGLV1-51_IGLJ2, Z3L1 Heavy chain | Authors: | Dai, L, Qi, J, Gao, G.F. | Deposit date: | 2020-03-23 | Release date: | 2021-03-24 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Protective Zika vaccines engineered to eliminate enhancement of dengue infection via immunodominance switch. Nat.Immunol., 22, 2021
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6CO8
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![BU of 6co8 by Molmil](/molmil-images/mine/6co8) | Structure of Zika virus at a resolution of 3.1 Angstrom | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, E protein, M protein | Authors: | Sevvana, M, Long, F, Miller, A.J, Klose, T, Buda, G, Sun, L, Kuhn, R.J, Rossmann, M.R. | Deposit date: | 2018-03-12 | Release date: | 2018-07-04 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Refinement and Analysis of the Mature Zika Virus Cryo-EM Structure at 3.1 angstrom Resolution. Structure, 26, 2018
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8CXI
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![BU of 8cxi by Molmil](/molmil-images/mine/8cxi) | Structures of Zika Virus in Complex with Antibodies Targeting E Dimer Epitopes and Basis for Neutralization Efficacy | Descriptor: | A11 heavy chain, A11 light chain, Ankyrin repeat family A protein 2,Envelope E protein, ... | Authors: | Liu, W, Zhang, X.K, Gong, D.Y, Dai, X.H, Sharma, A, Zhang, T.H, Rey, F, Zhou, Z.H. | Deposit date: | 2022-05-21 | Release date: | 2023-06-07 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structures of Zika Virus in Complex with Antibodies Targeting E Dimer Epitopes and Basis for Neutralization Efficacy To Be Published
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8EED
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![BU of 8eed by Molmil](/molmil-images/mine/8eed) | |
8EE5
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![BU of 8ee5 by Molmil](/molmil-images/mine/8ee5) | |
5IZ7
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![BU of 5iz7 by Molmil](/molmil-images/mine/5iz7) | Cryo-EM structure of thermally stable Zika virus strain H/PF/2013 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, structural protein E, structural protein M | Authors: | Kostyuchenko, V.A, Zhang, S, Fibriansah, G, Lok, S.M. | Deposit date: | 2016-03-25 | Release date: | 2016-05-25 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structure of the thermally stable Zika virus Nature, 533, 2016
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5IRE
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![BU of 5ire by Molmil](/molmil-images/mine/5ire) | The cryo-EM structure of Zika Virus | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, E protein, M protein | Authors: | Sirohi, D, Chen, Z, Sun, L, Klose, T, Pierson, T, Rossmann, M, Kuhn, R. | Deposit date: | 2016-03-13 | Release date: | 2016-03-30 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | The 3.8 angstrom resolution cryo-EM structure of Zika virus. Science, 352, 2016
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7BU8
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![BU of 7bu8 by Molmil](/molmil-images/mine/7bu8) | Cryo-EM structure of zika virus complexed with Fab SIgN-3C at pH 6.5 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Genome polyprotein, SIgN-3C Fab heavy chain, ... | Authors: | Zhang, S, Chew, S.V, Lim, X.N, Ng, T.S, Kostyuchenko, V.A, Lok, S.M. | Deposit date: | 2020-04-05 | Release date: | 2020-05-13 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | A Human Antibody Neutralizes Different Flaviviruses by Using Different Mechanisms. Cell Rep, 31, 2020
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6I7P
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![BU of 6i7p by Molmil](/molmil-images/mine/6i7p) | Crystal structure of the full-length Zika virus NS5 protein (Human isolate Z1106033) | Descriptor: | NS5, PHOSPHATE ION, S-ADENOSYL-L-HOMOCYSTEINE, ... | Authors: | Ferrero, D.S, Ruiz-Arroyo, V.M, Soler, N, Uson, I, Verdaguer, N. | Deposit date: | 2018-11-16 | Release date: | 2019-04-24 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.975 Å) | Cite: | Supramolecular arrangement of the full-length Zika virus NS5. Plos Pathog., 15, 2019
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6MID
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5H37
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![BU of 5h37 by Molmil](/molmil-images/mine/5h37) | Cryo-EM structure of zika virus complexed with Fab C10 at pH 8.0 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, C10 IgG heavy chain variable region, C10 IgG light chain variable region, ... | Authors: | Zhang, S, Kostyuchenko, V, Ng, T.-S, Lim, X.-N, Ooi, J.S.G, Lambert, S, Tan, T.Y, Widman, D, Shi, J, Baric, R.S, Lok, S.-M. | Deposit date: | 2016-10-20 | Release date: | 2016-11-30 | Last modified: | 2022-03-23 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Neutralization mechanism of a highly potent antibody against Zika virus Nat Commun, 7, 2016
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