6PLK

Crystal structure of ZIKV-116 Fab in complex with ZIKV envelope DIII

Summary for 6PLK

Entry DOI	10.2210/pdb6plk/pdb
Descriptor	ZIKV-116 heavy chain, ZIKV-116 light chain, Env, ... (4 entities in total)
Functional Keywords	human antibody, zikv-diii, antiviral protein, structural genomics, center for structural genomics of infectious diseases, csgid
Biological source	Homo sapiens More
Total number of polymer chains	6
Total formula weight	118949.84
Authors	Zhao, H.,Fremont, D.H.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2019-07-01, release date: 2019-11-20, Last modification date: 2023-10-11)
Primary citation	Zhao, H.,Xu, L.,Bombardi, R.,Nargi, R.,Deng, Z.,Errico, J.M.,Nelson, C.A.,Dowd, K.A.,Pierson, T.C.,Crowe, J.E.,Diamond, M.S.,Fremont, D.H. Mechanism of differential Zika and dengue virus neutralization by a public antibody lineage targeting the DIII lateral ridge. J.Exp.Med., 217:-, 2020 Cited by PubMed: 31757867 DOI: 10.1084/jem.20191792 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation