5LCV

Structural basis of Zika and Dengue virus potent antibody cross-neutralization

Summary for 5LCV

• Entry DOI: 10.2210/pdb5lcv/pdb
• Related: 5LBS 5LBV
• Descriptor: Polyprotein, BROADLY NEUTRALIZING HUMAN ANTIBODY EDE2 A11, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• Functional Keywords: immune system-viral protein complex, zika virus, broadly neutralizing antibody, viral protein, immune system, viral protein-immune system complex, viral protein/immune system
• Biological source: Zika virus (ZIKV); More
• Total number of polymer chains: 4
• Total formula weight: 151480.03

Authors

Barba-Spaeth, G. (deposition date: 2016-06-22, release date: 2016-07-06, Last modification date: 2024-01-10)

• Primary citation: Barba-Spaeth, G.,Dejnirattisai, W.,Rouvinski, A.,Vaney, M.C.,Medits, I.,Sharma, A.,Simon-Loriere, E.,Sakuntabhai, A.,Cao-Lormeau, V.M.,Haouz, A.,England, P.,Stiasny, K.,Mongkolsapaya, J.,Heinz, F.X.,Screaton, G.R.,Rey, F.A.; Structural basis of potent Zika-dengue virus antibody cross-neutralization.; Nature, 536:48-53, 2016; PubMed: 27338953; DOI: 10.1038/nature18938

Experimental method

X-RAY DIFFRACTION (2.64 Å)