5LCV
Structural basis of Zika and Dengue virus potent antibody cross-neutralization
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Polyprotein | polymer | 447 | 48492.5 | 2 | UniProt (A0A120IIH9) Pfam (PF00869) Pfam (PF02832) UniProt (by SIFTS) (A0A024B7W1) | Zika virus (ZIKV) | |
| 2 | C (H) | BROADLY NEUTRALIZING HUMAN ANTIBODY EDE2 A11 | polymer | 283 | 30355.5 | 1 | Homo sapiens | ||
| 3 | D (L) | BROADLY NEUTRALIZING HUMAN ANTIBODY EDE2 A11 | polymer | 216 | 22863.4 | 1 | Homo sapiens | ||
| 4 | E (C) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 1 | In PDB GlyTouCan (G32152BH) | |||
| 5 | F (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 6 | G, H, J (A, B) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 7 | I (A) | FORMIC ACID | non-polymer | 46.0 | 1 | Chemie (FMT) | |||
| 8 | K, L, M, N (A, B, H, L) | water | water | 18.0 | 40 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 408 (UniProt: A0A120IIH9)
| PDB | External Database | Details |
|---|---|---|
| Gly 409 | - | expression tag |
| Pro 410 | - | expression tag |
| Phe 411 | - | expression tag |
| Glu 412 | - | expression tag |
| Asp 413 | - | expression tag |
| Asp 414 | - | expression tag |
| Asp 415 | - | expression tag |
| Asp 416 | - | expression tag |
| Lys 417 | - | expression tag |
| Ala 418 | - | expression tag |
| Gly 419 | - | expression tag |
| Trp 420 | - | expression tag |
| Ser 421 | - | expression tag |
| His 422 | - | expression tag |
| Pro 423 | - | expression tag |
| Gln 424 | - | expression tag |
| Phe 425 | - | expression tag |
| Glu 426 | - | expression tag |
| Lys 427 | - | expression tag |
| Gly 428 | - | expression tag |
| Gly 429 | - | expression tag |
| Gly 430 | - | expression tag |
| Ser 431 | - | expression tag |
| Gly 432 | - | expression tag |
| Gly 433 | - | expression tag |
| Gly 434 | - | expression tag |
| Ser 435 | - | expression tag |
| Gly 436 | - | expression tag |
| Gly 437 | - | expression tag |
| Gly 438 | - | expression tag |
| Ser 439 | - | expression tag |
| Trp 440 | - | expression tag |
| Ser 441 | - | expression tag |
| His 442 | - | expression tag |
| Pro 443 | - | expression tag |
| Gln 444 | - | expression tag |
| Phe 445 | - | expression tag |
| Glu 446 | - | expression tag |
| Lys 447 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 150203.8 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 732.7 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 543.5 | |
| All* | Total formula weight | 151480.0 |
