5LCV
Structural basis of Zika and Dengue virus potent antibody cross-neutralization
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Polyprotein | polymer | 447 | 48492.5 | 2 | UniProt (A0A120IIH9) Pfam (PF00869) Pfam (PF02832) UniProt (by SIFTS) (A0A024B7W1) In PDB | Zika virus (ZIKV) | |
2 | H | BROADLY NEUTRALIZING HUMAN ANTIBODY EDE2 A11 | polymer | 283 | 30355.5 | 1 | Homo sapiens | ||
3 | L | BROADLY NEUTRALIZING HUMAN ANTIBODY EDE2 A11 | polymer | 216 | 22863.4 | 1 | Homo sapiens | ||
4 | C | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 1 | In PDB GlyTouCan (G32152BH) | |||
5 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
6 | A, B | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
7 | A | FORMIC ACID | non-polymer | 46.0 | 1 | Chemie (FMT) | |||
8 | water | water | 18.0 | 40 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 408 (UniProt: A0A120IIH9)
PDB | External Database | Details |
---|---|---|
Gly 409 | - | expression tag |
Pro 410 | - | expression tag |
Phe 411 | - | expression tag |
Glu 412 | - | expression tag |
Asp 413 | - | expression tag |
Asp 414 | - | expression tag |
Asp 415 | - | expression tag |
Asp 416 | - | expression tag |
Lys 417 | - | expression tag |
Ala 418 | - | expression tag |
Gly 419 | - | expression tag |
Trp 420 | - | expression tag |
Ser 421 | - | expression tag |
His 422 | - | expression tag |
Pro 423 | - | expression tag |
Gln 424 | - | expression tag |
Phe 425 | - | expression tag |
Glu 426 | - | expression tag |
Lys 427 | - | expression tag |
Gly 428 | - | expression tag |
Gly 429 | - | expression tag |
Gly 430 | - | expression tag |
Ser 431 | - | expression tag |
Gly 432 | - | expression tag |
Gly 433 | - | expression tag |
Gly 434 | - | expression tag |
Ser 435 | - | expression tag |
Gly 436 | - | expression tag |
Gly 437 | - | expression tag |
Gly 438 | - | expression tag |
Ser 439 | - | expression tag |
Trp 440 | - | expression tag |
Ser 441 | - | expression tag |
His 442 | - | expression tag |
Pro 443 | - | expression tag |
Gln 444 | - | expression tag |
Phe 445 | - | expression tag |
Glu 446 | - | expression tag |
Lys 447 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 150203.8 | |
Branched | Number of molecules | 1 |
Total formula weight | 732.7 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 543.5 | |
All* | Total formula weight | 151480.0 |