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PDB: 891 results

5CJQ
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Crystal structure of a trimeric influenza hemagglutinin stem in complex with an broadly neutralizing antibody CR9114
Descriptor: CR9114 heavy chain, CR9114 light chain, Designed influenza hemagglutinin stem #4900, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2015-07-14
Release date:2015-09-09
Last modified:2015-09-30
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:A stable trimeric influenza hemagglutinin stem as a broadly protective immunogen.
Science, 349, 2015
5CEX
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Crystal Structure of Fab 32H+109L, a putative precursor of the PGT121 family of potent HIV-1 antibodies
Descriptor: Antibody 9H+3L Fab heavy chain, Antibody 9H+3L Fab light chain, GLYCEROL, ...
Authors:Garces, F, Wilson, I.A.
Deposit date:2015-07-07
Release date:2015-12-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.105 Å)
Cite:Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans.
Immunity, 43, 2015
2F58
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IGG1 FAB FRAGMENT (58.2) COMPLEX WITH 12-RESIDUE CYCLIC PEPTIDE (INCLUDING RESIDUES 315-324 OF HIV-1 GP120) (MN ISOLATE)
Descriptor: 1-IMINO-5-PENTANONE, PROTEIN (HIV-1 GP120), PROTEIN (IGG1 FAB 58.2 ANTIBODY (HEAVY CHAIN)), ...
Authors:Stanfield, R.L, Cabezas, E, Satterthwait, A.C, Stura, E.A, Profy, A.T, Wilson, I.A.
Deposit date:1998-10-23
Release date:1999-02-09
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Dual conformations for the HIV-1 gp120 V3 loop in complexes with different neutralizing fabs.
Structure Fold.Des., 7, 1999
5CJS
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Crystal structure of a monomeric influenza hemagglutinin stem in complex with an broadly neutralizing antibody CR9114
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CR9114 heavy chain, CR9114 light chain, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2015-07-15
Release date:2015-09-09
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (4.3 Å)
Cite:A stable trimeric influenza hemagglutinin stem as a broadly protective immunogen.
Science, 349, 2015
1A3L
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BU of 1a3l by Molmil
CATALYSIS OF A DISFAVORED REACTION: AN ANTIBODY EXO DIELS-ALDERASE-TSA-INHIBITOR COMPLEX AT 1.95 A RESOLUTION
Descriptor: 1-CARBOXY-1'-[(DIMETHYLAMINO)-CARBONYL]FERROCENE, IMMUNOGLOBULIN FAB 13G5 (HEAVY CHAIN), IMMUNOGLOBULIN FAB 13G5 (LIGHT CHAIN)
Authors:Heine, A, Wilson, I.A.
Deposit date:1998-01-22
Release date:1999-02-16
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:An antibody exo Diels-Alderase inhibitor complex at 1.95 angstrom resolution.
Science, 279, 1998
2FX9
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BU of 2fx9 by Molmil
Crystal structure of hiv-1 neutralizing human fab 4e10 in complex with a thioether-linked peptide encompassing the 4e10 epitope on gp41
Descriptor: Fab 4E10, Fragment of HIV glycoprotein gp41
Authors:Cardoso, R.M.F, Brunel, F.M, Ferguson, S, Burton, D.R, Dawson, P.E, Wilson, I.A.
Deposit date:2006-02-03
Release date:2006-12-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of enhanced binding of extended and helically constrained peptide epitopes of the broadly neutralizing HIV-1 antibody 4E10.
J.Mol.Biol., 365, 2007
1AI1
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BU of 1ai1 by Molmil
HIV-1 V3 LOOP MIMIC
Descriptor: AIB142, IGG1-KAPPA 59.1 FAB (HEAVY CHAIN), IGG1-KAPPA 59.1 FAB (LIGHT CHAIN)
Authors:Ghiara, J.B, Wilson, I.A.
Deposit date:1996-11-06
Release date:1997-05-15
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure-based design of a constrained peptide mimic of the HIV-1 V3 loop neutralization site.
J.Mol.Biol., 266, 1997
3CYE
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BU of 3cye by Molmil
Cyrstal structure of the native 1918 H1N1 neuraminidase from a crystal with lattice-translocation defects
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CALCIUM ION, ...
Authors:Zhu, X, Xu, X, Wilson, I.A.
Deposit date:2008-04-25
Release date:2008-08-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure determination of the 1918 H1N1 neuraminidase from a crystal with lattice-translocation defects
Acta Crystallogr.,Sect.D, 64, 2008
2FX8
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Crystal structure of hiv-1 neutralizing human fab 4e10 in complex with an aib-induced peptide encompassing the 4e10 epitope on gp41
Descriptor: Fab 4E10, Fragment of HIV glycoprotein (GP41)
Authors:Cardoso, R.M.F, Brunel, F.M, Ferguson, S, Burton, D.R, Dawson, P.E, Wilson, I.A.
Deposit date:2006-02-03
Release date:2006-12-19
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis of enhanced binding of extended and helically constrained peptide epitopes of the broadly neutralizing HIV-1 antibody 4E10.
J.Mol.Biol., 365, 2007
5E35
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Crystal structure of H5 hemagglutinin mutant (N224K, Q226L, N158D and L133a deletion) from the influenza virus A/chicken/Vietnam/NCVD-093/2008 (H5N1) with LSTc
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Zhu, X, Wilson, I.A.
Deposit date:2015-10-01
Release date:2015-12-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Basis for a Switch in Receptor Binding Specificity of Two H5N1 Hemagglutinin Mutants.
Cell Rep, 13, 2015
5E2Z
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BU of 5e2z by Molmil
Crystal structure of H5 hemagglutinin Q226L mutant from the influenza virus A/duck/Egypt/10185SS/2010 (H5N1) with LSTa
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2015-10-01
Release date:2015-12-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.624 Å)
Cite:Structural Basis for a Switch in Receptor Binding Specificity of Two H5N1 Hemagglutinin Mutants.
Cell Rep, 13, 2015
5E32
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BU of 5e32 by Molmil
Crystal structure of H5 hemagglutinin mutant (N224K, Q226L, N158D and L133a deletion) from the influenza virus A/chicken/Vietnam/NCVD-093/2008 (H5N1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin
Authors:Zhu, X, Wilson, I.A.
Deposit date:2015-10-01
Release date:2015-12-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Basis for a Switch in Receptor Binding Specificity of Two H5N1 Hemagglutinin Mutants.
Cell Rep, 13, 2015
5E2Y
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BU of 5e2y by Molmil
Crystal structure of H5 hemagglutinin Q226L mutant from the influenza virus A/duck/Egypt/10185SS/2010 (H5N1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, beta-L-fucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2015-10-01
Release date:2015-12-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Basis for a Switch in Receptor Binding Specificity of Two H5N1 Hemagglutinin Mutants.
Cell Rep, 13, 2015
5E99
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BU of 5e99 by Molmil
Bovine Fab fragment F08_B11
Descriptor: Fab F08_B11 heavy chain, Fab F08_B11 light chain
Authors:Stanfield, R.L, Wilson, I.A.
Deposit date:2015-10-14
Release date:2016-08-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Conservation and diversity in the ultralong third heavy-chain complementarity-determining region of bovine antibodies.
Sci Immunol, 1, 2016
5E30
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BU of 5e30 by Molmil
Crystal structure of H5 hemagglutinin Q226L mutant from the influenza virus A/duck/Egypt/10185SS/2010 (H5N1) with LSTc
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2015-10-01
Release date:2015-12-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Basis for a Switch in Receptor Binding Specificity of Two H5N1 Hemagglutinin Mutants.
Cell Rep, 13, 2015
1ACY
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BU of 1acy by Molmil
CRYSTAL STRUCTURE OF THE PRINCIPAL NEUTRALIZING SITE OF HIV-1
Descriptor: HIV-1 GP120 (MN ISOLATE), IGG1-KAPPA 59.1 FAB (HEAVY CHAIN), IGG1-KAPPA 59.1 FAB (LIGHT CHAIN)
Authors:Ghiara, J.B, Wilson, I.A.
Deposit date:1994-02-10
Release date:1994-07-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of the principal neutralization site of HIV-1.
Science, 264, 1994
5E34
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BU of 5e34 by Molmil
Crystal structure of H5 hemagglutinin mutant (N224K, Q226L, N158D and L133a deletion) from the influenza virus A/chicken/Vietnam/NCVD-093/2008 (H5N1) with LSTa
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Zhu, X, Wilson, I.A.
Deposit date:2015-10-01
Release date:2015-12-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Basis for a Switch in Receptor Binding Specificity of Two H5N1 Hemagglutinin Mutants.
Cell Rep, 13, 2015
1AHW
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BU of 1ahw by Molmil
A COMPLEX OF EXTRACELLULAR DOMAIN OF TISSUE FACTOR WITH AN INHIBITORY FAB (5G9)
Descriptor: IMMUNOGLOBULIN FAB 5G9 (HEAVY CHAIN), IMMUNOGLOBULIN FAB 5G9 (LIGHT CHAIN), TISSUE FACTOR
Authors:Huang, M, Syed, R, Stura, E.A, Stone, M.J, Stefanko, R.S, Ruf, W, Edgington, T.S, Wilson, I.A.
Deposit date:1997-04-10
Release date:1998-02-25
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (3 Å)
Cite:The mechanism of an inhibitory antibody on TF-initiated blood coagulation revealed by the crystal structures of human tissue factor, Fab 5G9 and TF.5G9 complex.
J.Mol.Biol., 275, 1998
2FX7
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BU of 2fx7 by Molmil
Crystal structure of hiv-1 neutralizing human fab 4e10 in complex with a 16-residue peptide encompassing the 4e10 epitope on gp41
Descriptor: Fab 4E10, Fragment of HIV glycoprotein (GP41), GLYCEROL
Authors:Cardoso, R.M.F, Brunel, F.M, Ferguson, S, Burton, D.R, Dawson, P.E, Wilson, I.A.
Deposit date:2006-02-03
Release date:2006-12-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Structural basis of enhanced binding of extended and helically constrained peptide epitopes of the broadly neutralizing HIV-1 antibody 4E10.
J.Mol.Biol., 365, 2007
2IGF
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BU of 2igf by Molmil
CRYSTAL STRUCTURES OF AN ANTIBODY TO A PEPTIDE AND ITS COMPLEX WITH PEPTIDE ANTIGEN AT 2.8 ANGSTROMS
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, IGG1-KAPPA B13I2 FAB (HEAVY CHAIN), IGG1-KAPPA B13I2 FAB (LIGHT CHAIN), ...
Authors:Stanfield, R.L, Wilson, I.A.
Deposit date:1991-03-21
Release date:1992-04-15
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of an antibody to a peptide and its complex with peptide antigen at 2.8 A.
Science, 248, 1990
8F0I
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BU of 8f0i by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain in complex with human antibody COVA309-22
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, COVA309-22 heavy chain, COVA309-22 light chain, ...
Authors:Yuan, M, Wilson, I.A.
Deposit date:2022-11-03
Release date:2023-09-13
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Broad SARS-CoV-2 neutralization by monoclonal and bispecific antibodies derived from a Gamma-infected individual.
Iscience, 26, 2023
6CK8
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BU of 6ck8 by Molmil
Crystal structure of anti-influenza single-domain llama antibody SD38
Descriptor: GLYCEROL, Llama antibody SD38, PENTAETHYLENE GLYCOL, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2018-02-27
Release date:2018-11-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin.
Science, 362, 2018
7JMW
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BU of 7jmw by Molmil
Crystal structure of SARS-CoV-2 spike protein receptor-binding domain in complex with cross-neutralizing antibody COVA1-16 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COVA1-16 heavy chain, COVA1-16 light chain, ...
Authors:Liu, H, Yuan, M, Zhu, X, Wu, N.C, Wilson, I.A.
Deposit date:2020-08-03
Release date:2020-10-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Cross-Neutralization of a SARS-CoV-2 Antibody to a Functionally Conserved Site Is Mediated by Avidity.
Immunity, 53, 2020
1IAO
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BU of 1iao by Molmil
CLASS II MHC I-AD IN COMPLEX WITH OVALBUMIN PEPTIDE 323-339
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, MHC CLASS II I-AD
Authors:Scott, C.A, Peterson, P.A, Teyton, L, Wilson, I.A.
Deposit date:1998-03-13
Release date:1998-11-04
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures of two I-Ad-peptide complexes reveal that high affinity can be achieved without large anchor residues.
Immunity, 8, 1998
1XZ0
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BU of 1xz0 by Molmil
Crystal structure of CD1a in complex with a synthetic mycobactin lipopeptide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 6-(HYDROXY-HEXADECANOYL-AMINO)-2-{[(4S)-2-(2-HYDROXY-PHENYL)-4,5-DIHYDRO-OXAZOLE-4-CARBONYL]-AMINO}-HEXANOIC ACID 2-[(3S)-1-(TERT-BUTYL-DIPHENYL-SILANYLOXY)-2-OXO-AZEPAN-3-YLCARBAMOYL]-(1S)-1-METHYL-ETHYL ESTER, Beta-2-microglobulin, ...
Authors:Zajonc, D.M, Crispin, M.D, Bowden, T.A, Young, D.C, Cheng, T.Y, Hu, J, Costello, C.E, Miller, M.J, Moody, D.B, Wilson, I.A.
Deposit date:2004-11-11
Release date:2005-03-01
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Molecular Mechanism of Lipopeptide Presentation by CD1a.
Immunity, 22, 2005

224201

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