6CK8

Crystal structure of anti-influenza single-domain llama antibody SD38

Summary for 6CK8

• Entry DOI: 10.2210/pdb6ck8/pdb
• Descriptor: Llama antibody SD38, SULFATE ION, PENTAETHYLENE GLYCOL, ... (5 entities in total)
• Functional Keywords: single-domain, multi-domain, llama, antibody, influenza, broad, neutralization, immune system
• Biological source: Lama glama
• Total number of polymer chains: 3
• Total formula weight: 43484.50

Authors

Zhu, X.,Wilson, I.A. (deposition date: 2018-02-27, release date: 2018-11-14, Last modification date: 2023-10-04)

• Primary citation: Laursen, N.S.,Friesen, R.H.E.,Zhu, X.,Jongeneelen, M.,Blokland, S.,Vermond, J.,van Eijgen, A.,Tang, C.,van Diepen, H.,Obmolova, G.,van der Neut Kolfschoten, M.,Zuijdgeest, D.,Straetemans, R.,Hoffman, R.M.B.,Nieusma, T.,Pallesen, J.,Turner, H.L.,Bernard, S.M.,Ward, A.B.,Luo, J.,Poon, L.L.M.,Tretiakova, A.P.,Wilson, J.M.,Limberis, M.P.,Vogels, R.,Brandenburg, B.,Kolkman, J.A.,Wilson, I.A.; Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin.; Science, 362:598-602, 2018; PubMed: 30385580; DOI: 10.1126/science.aaq0620

Experimental method

X-RAY DIFFRACTION (2.05 Å)