1A3L

CATALYSIS OF A DISFAVORED REACTION: AN ANTIBODY EXO DIELS-ALDERASE-TSA-INHIBITOR COMPLEX AT 1.95 A RESOLUTION

Summary for 1A3L

DescriptorIMMUNOGLOBULIN FAB 13G5 (LIGHT CHAIN), IMMUNOGLOBULIN FAB 13G5 (HEAVY CHAIN), 1-CARBOXY-1'-[(DIMETHYLAMINO)-CARBONYL]FERROCENE, ... (4 entities in total)
Functional Keywordsdiels-alder, disfavored reaction, catalytic antibody, immunoglobulin
Biological sourceMus musculus (house mouse)
Total number of polymer chains2
Total molecular weight47308.37
Authors
Heine, A.,Wilson, I.A. (deposition date: 1998-01-22, release date: 1999-02-16, Last modification date: 2011-07-13)
Primary citation
Heine, A.,Stura, E.A.,Yli-Kauhaluoma, J.T.,Gao, C.,Deng, Q.,Beno, B.R.,Houk, K.N.,Janda, K.D.,Wilson, I.A.
An antibody exo Diels-Alderase inhibitor complex at 1.95 angstrom resolution.
Science, 279:1934-1940, 1998
PubMed: 9506943 (PDB entries with the same primary citation)
DOI: 10.1126/science.279.5358.1934
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.95 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers60.7%5.6%0.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution