1ACY

CRYSTAL STRUCTURE OF THE PRINCIPAL NEUTRALIZING SITE OF HIV-1

Summary for 1ACY

Entry DOI	10.2210/pdb1acy/pdb
Descriptor	IGG1-KAPPA 59.1 FAB (LIGHT CHAIN), IGG1-KAPPA 59.1 FAB (HEAVY CHAIN), HIV-1 GP120 (MN ISOLATE) (3 entities in total)
Functional Keywords	complex(antibody-hiv-1 fragment), complex(antibody-hiv-1 fragment) complex, complex(antibody/hiv-1 fragment)
Biological source	Mus musculus (house mouse) More
Cellular location	Cell membrane; Single-pass membrane protein (Potential): P01869 Transmembrane protein gp41: Virion membrane; Single-pass type I membrane protein. Surface protein gp120: Virion membrane; Peripheral membrane protein: P05877
Total number of polymer chains	3
Total formula weight	50697.83
Authors	Ghiara, J.B.,Wilson, I.A. (deposition date: 1994-02-10, release date: 1994-07-31, Last modification date: 2011-07-13)
Primary citation	Ghiara, J.B.,Stura, E.A.,Stanfield, R.L.,Profy, A.T.,Wilson, I.A. Crystal structure of the principal neutralization site of HIV-1. Science, 264:82-85, 1994 Cited by PubMed: 7511253 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation