2V0G
 
 | | LEUCYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS COMPLEXED WITH A tRNA(leu) transcript with 5-FLUORO-1,3-DIHYDRO-1-HYDROXY-2,1- BENZOXABOROLE (AN2690) forming an adduct to the ribose of adenosine- 76 in the enzyme editing site. | | 分子名称: | AMINOACYL-TRNA SYNTHETASE, LEUCINE, MERCURY (II) ION, ... | | 著者 | Rock, F, Mao, W, Yaremchuk, A, Tukalo, M, Crepin, T, Zhou, H, Zhang, Y, Hernandez, V, Akama, T, Baker, S, Plattner, J, Shapiro, L, Martinis, S.A, Benkovic, S.J, Cusack, S, Alley, M.R.K. | | 登録日 | 2007-05-14 | | 公開日 | 2007-07-03 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | An Antifungal Agent Inhibits an Aminoacyl-tRNA Synthetase by Trapping tRNA in the Editing Site.
Science, 316, 2007
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2MC7
 | | Structure of Salmonella MgtR | | 分子名称: | Regulatory peptide | | 著者 | Jean-Francois, F, Dai, J, Yu, L, Myrick, A, Rubin, E, Fajer, P, Song, L, Zhou, H, Cross, T. | | 登録日 | 2013-08-15 | | 公開日 | 2013-10-30 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLID-STATE NMR | | 主引用文献 | Binding of MgtR, a Salmonella Transmembrane Regulatory Peptide, to MgtC, a Mycobacterium tuberculosis Virulence Factor: A Structural Study.
J.Mol.Biol., 426, 2014
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1K0S
 | | Solution structure of the chemotaxis protein CheW from the thermophilic organism Thermotoga maritima | | 分子名称: | CHEMOTAXIS PROTEIN CHEW | | 著者 | Griswold, I.J, Zhou, H, Swanson, R.V, Simon, M.I, Dahlquist, F.W. | | 登録日 | 2001-09-20 | | 公開日 | 2002-02-06 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The solution structure and interactions of CheW from Thermotoga maritima.
Nat.Struct.Biol., 9, 2002
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2MMU
 | | Structure of CrgA, a Cell Division Structural and Regulatory Protein from Mycobacterium tuberculosis, in Lipid Bilayers | | 分子名称: | Cell division protein CrgA | | 著者 | Das, N, Dai, J, Hung, I, Rajagopalan, M, Zhou, H, Cross, T.A. | | 登録日 | 2014-03-18 | | 公開日 | 2014-12-17 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLID-STATE NMR | | 主引用文献 | Structure of CrgA, a cell division structural and regulatory protein from Mycobacterium tuberculosis, in lipid bilayers.
Proc.Natl.Acad.Sci.USA, 112, 2015
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5ZNK
 | | Crystal structure of a bacterial ProRS with ligands | | 分子名称: | 7-chloro-6-fluoro-3-{2-oxo-3-[(2S)-piperidin-2-yl]propyl}quinazolin-4(3H)-one, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Cheng, B, Yu, Y, Zhou, H. | | 登録日 | 2018-04-09 | | 公開日 | 2019-05-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | | 主引用文献 | Structure-Guided Design of Halofuginone Derivatives as ATP-Aided Inhibitors Against Bacterial Prolyl-tRNA Synthetase.
J.Med.Chem., 65, 2022
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5ZNJ
 | | Crystal structure of a bacterial ProRS with ligands | | 分子名称: | 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Cheng, B, Yu, Y, Zhou, H. | | 登録日 | 2018-04-09 | | 公開日 | 2019-05-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | Structure-Guided Design of Halofuginone Derivatives as ATP-Aided Inhibitors Against Bacterial Prolyl-tRNA Synthetase.
J.Med.Chem., 65, 2022
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5Z9P
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6L2P
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6L4L
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6L9J
 | | Structure of yeast Snf5 and Swi3 subcomplex | | 分子名称: | GLYCEROL, SWI/SNF chromatin-remodeling complex subunit SNF5, SWI/SNF complex subunit SWI3 | | 著者 | Long, J, Zhou, H. | | 登録日 | 2019-11-10 | | 公開日 | 2020-11-11 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.642 Å) | | 主引用文献 | Snf5 and Swi3 subcomplex formation is required for SWI/SNF complex function in yeast.
Biochem.Biophys.Res.Commun., 526, 2020
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6L2Q
 | | Threonyl-tRNA synthetase from Salmonella enterica in complex with an inhibitor | | 分子名称: | (2S,3R)-2-azanyl-N-[(E)-4-[6,7-bis(chloranyl)-4-oxidanylidene-quinazolin-3-yl]but-2-enyl]-3-oxidanyl-butanamide, 1,2-ETHANEDIOL, Threonine--tRNA ligase, ... | | 著者 | Guo, J, Chen, B, Zhou, H. | | 登録日 | 2019-10-05 | | 公開日 | 2020-01-15 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Discovery of novel tRNA-amino acid dual-site inhibitors against threonyl-tRNA synthetase by fragment-based target hopping.
Eur.J.Med.Chem., 187, 2019
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6LQI
 | | Cryo-EM structure of the mouse Piezo1 isoform Piezo1.1 | | 分子名称: | Piezo-type mechanosensitive ion channel component 1 | | 著者 | Geng, J, Liu, W, Zhou, H, Zhang, T, Wang, L, Zhang, M, Shen, B, Li, X, Xiao, B. | | 登録日 | 2020-01-13 | | 公開日 | 2020-03-04 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | A Plug-and-Latch Mechanism for Gating the Mechanosensitive Piezo Channel.
Neuron, 106, 2020
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4Y25
 | | Bacterial polysaccharide outer membrane secretin | | 分子名称: | Poly-beta-1,6-N-acetyl-D-glucosamine export protein | | 著者 | Wang, Y, AndolePannuri, A, Ni, D, Zhou, H, Cao, X, Lu, X, Romeo, T, Huang, Y. | | 登録日 | 2015-02-09 | | 公開日 | 2016-03-16 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.821 Å) | | 主引用文献 | Structural Basis for Translocation of a Biofilm-supporting Exopolysaccharide across the Bacterial Outer Membrane
J.Biol.Chem., 291, 2016
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5J0A
 | | Crystal structure of PDZ-binding kinase | | 分子名称: | 4'-HYDROXYCINNAMIC ACID, Lymphokine-activated killer T-cell-originated protein kinase, SULFATE ION | | 著者 | Zou, Q.W, Zhou, H, Yang, X. | | 登録日 | 2016-03-28 | | 公開日 | 2016-09-07 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | | 主引用文献 | The crystal structure of an inactive dimer of PDZ-binding kinase
Biochem.Biophys.Res.Commun., 476, 2016
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8YA4
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8Y9W
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8Y9V
 | | ZIKV NS2B/NS3 protease | | 分子名称: | DAR-LYS-ORN-ARG, Serine protease NS3, Serine protease subunit NS2B | | 著者 | Zhang, C.Y, Xu, Q, Wang, W.W, Zhou, H, Wang, Q.S. | | 登録日 | 2024-02-07 | | 公開日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystallographic data collection using a multilayer monochromator on an undulator beamline at SSRF
To Be Published
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8YA1
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8YA5
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7TSX
 | | Structure of Enterobacter cloacae Cap2 bound to CdnD02 C-terminus, Apo state | | 分子名称: | Cap2, Cyclic AMP-AMP-GMP synthase | | 著者 | Ye, Q, Gu, Y, Ledvina, H.E, Quan, Y, Lau, R.K, Zhou, H, Whiteley, A.T, Corbett, K.D. | | 登録日 | 2022-01-31 | | 公開日 | 2023-01-11 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | An E1-E2 fusion protein primes antiviral immune signalling in bacteria.
Nature, 616, 2023
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7TQD
 | | Structure of Enterobacter cloacae Cap2-CdnD02 2:1 complex | | 分子名称: | ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Gu, Y, Ye, Q, Ledvina, H.E, Quan, Y, Lau, R.K, Zhou, H, Whiteley, A.T, Corbett, K.D. | | 登録日 | 2022-01-26 | | 公開日 | 2023-01-11 | | 最終更新日 | 2023-04-26 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | An E1-E2 fusion protein primes antiviral immune signalling in bacteria.
Nature, 616, 2023
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7TSQ
 | | Structure of Enterobacter cloacae Cap2 bound to CdnD02 C-terminus, AMP state | | 分子名称: | ADENOSINE MONOPHOSPHATE, Cap2, Cyclic AMP-AMP-GMP synthase, ... | | 著者 | Ye, Q, Gu, Y, Ledvina, H.E, Quan, Y, Lau, R.K, Zhou, H, Whiteley, A.T, Corbett, K.D. | | 登録日 | 2022-01-31 | | 公開日 | 2023-01-11 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | | 主引用文献 | An E1-E2 fusion protein primes antiviral immune signalling in bacteria.
Nature, 616, 2023
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7TO3
 | | Structure of Enterobacter cloacae Cap2-CdnD02 2:2 complex | | 分子名称: | ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Gu, Y, Ye, Q, Ledvina, H.E, Quan, Y, Lau, R.K, Zhou, H, Whiteley, A.T, Corbett, K.D. | | 登録日 | 2022-01-22 | | 公開日 | 2023-01-11 | | 最終更新日 | 2023-04-26 | | 実験手法 | ELECTRON MICROSCOPY (2.74 Å) | | 主引用文献 | An E1-E2 fusion protein primes antiviral immune signalling in bacteria.
Nature, 616, 2023
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7TIL
 | | CryoEM structure of JetD from Pseudomonas aeruginosa | | 分子名称: | JetD | | 著者 | Deep, A, Gu, Y, Gao, Y, Ego, K, Herzik, M, Zhou, H, Corbett, K. | | 登録日 | 2022-01-13 | | 公開日 | 2022-10-05 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | The SMC-family Wadjet complex protects bacteria from plasmid transformation by recognition and cleavage of closed-circular DNA.
Mol.Cell, 82, 2022
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5GM2
 | | Crystal structure of methyltransferase TleD complexed with SAH and teleocidin A1 | | 分子名称: | (2S,5S)-9-[(3R)-3,7-dimethylocta-1,6-dien-3-yl]-5-(hydroxymethyl)-1-methyl-2-(propan-2-yl)-1,2,4,5,6,8-hexahydro-3H-[1,4]diazonino[7,6,5-cd]indol-3-one, O-methylransferase, S-ADENOSYL-L-HOMOCYSTEINE | | 著者 | Yu, F, Li, M.J, Xu, C.Y, Zhou, H, Sun, B, Wang, Z.J, Xu, Q, Xie, M.Y, Zuo, G, Huang, P, Wang, Q.S, He, J.H. | | 登録日 | 2016-07-12 | | 公開日 | 2016-09-28 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure and enantioselectivity of terpene cyclization in SAM-dependent methyltransferase TleD
Biochem.J., 473, 2016
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