7VDF
 
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7VD9
 | | 2.29 A structure of the human catalase | | 分子名称: | Catalase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Fan, H.C, Zhang, Y, Sun, F. | | 登録日 | 2021-09-06 | | 公開日 | 2021-12-29 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (2.29 Å) | | 主引用文献 | A cryo-electron microscopy support film formed by 2D crystals of hydrophobin HFBI.
Nat Commun, 12, 2021
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7C7Q
 | | Cryo-EM structure of the baclofen/BHFF-bound human GABA(B) receptor in active state | | 分子名称: | (3S)-5,7-ditert-butyl-3-oxidanyl-3-(trifluoromethyl)-1-benzofuran-2-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid type B receptor subunit 1, ... | | 著者 | Mao, C, Shen, C, Li, C, Shen, D, Xu, C, Zhang, S, Zhou, R, Shen, Q, Chen, L, Jiang, Z, Liu, J, Zhang, Y. | | 登録日 | 2020-05-26 | | 公開日 | 2020-07-01 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Cryo-EM structures of inactive and active GABABreceptor.
Cell Res., 30, 2020
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7EU8
 | | Structure of the human GluN1-GluN2B NMDA receptor in complex with S-ketamine,glycine and glutamate | | 分子名称: | (2~{S})-2-(2-chlorophenyl)-2-(methylamino)cyclohexan-1-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... | | 著者 | Zhang, T, Zhang, Y, Zhu, S. | | 登録日 | 2021-05-16 | | 公開日 | 2021-07-28 | | 最終更新日 | 2022-10-26 | | 実験手法 | ELECTRON MICROSCOPY (4.07 Å) | | 主引用文献 | Structural basis of ketamine action on human NMDA receptors.
Nature, 596, 2021
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7VMW
 | | Crystal structure of LimF prenyltransferase bound with a peptide substrate and GSPP | | 分子名称: | GERANYL S-THIOLODIPHOSPHATE, LynF/TruF/PatF family peptide O-prenyltransferase, MAGNESIUM ION, ... | | 著者 | Hamada, K, Kobayashi, S, Okada, C, Zhang, Y, Inoue, S, Goto, Y, Suga, H, Ogata, K, Sengoku, T. | | 登録日 | 2021-10-09 | | 公開日 | 2022-08-03 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | LimF is a versatile prenyltransferase for histidine-C-geranylation on diverse non-natural substrates
Nat Catal, 2022
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7C7S
 | | Cryo-EM structure of the CGP54626-bound human GABA(B) receptor in inactive state. | | 分子名称: | (R)-(cyclohexylmethyl)[(2S)-3-{[(1S)-1-(3,4-dichlorophenyl)ethyl]amino}-2-hydroxypropyl]phosphinic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid type B receptor subunit 1, ... | | 著者 | Mao, C, Shen, C, Li, C, Shen, D, Xu, C, Zhang, S, Zhou, R, Shen, Q, Chen, L, Jiang, Z, Liu, J, Zhang, Y. | | 登録日 | 2020-05-26 | | 公開日 | 2020-07-01 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Cryo-EM structures of inactive and active GABABreceptor.
Cell Res., 30, 2020
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7TVK
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7ROM
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7VYU
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8HIG
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7CYQ
 | | Cryo-EM structure of an extended SARS-CoV-2 replication and transcription complex reveals an intermediate state in cap synthesis | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Helicase, MAGNESIUM ION, ... | | 著者 | Yan, L, Ge, J, Zheng, L, Zhang, Y, Gao, Y, Wang, T, Wang, H, Huang, Y, Li, M, Wang, Q, Rao, Z, Lou, Z. | | 登録日 | 2020-09-04 | | 公開日 | 2020-12-09 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (2.83 Å) | | 主引用文献 | Cryo-EM Structure of an Extended SARS-CoV-2 Replication and Transcription Complex Reveals an Intermediate State in Cap Synthesis.
Cell, 184, 2021
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7VMY
 | | Crystal structure of LimF prenyltransferase bound with GSPP | | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GERANYL S-THIOLODIPHOSPHATE, LynF/TruF/PatF family peptide O-prenyltransferase, ... | | 著者 | Hamada, K, Kobayashi, S, Okada, C, Zhang, Y, Inoue, S, Goto, Y, Suga, H, Ogata, K, Sengoku, T. | | 登録日 | 2021-10-09 | | 公開日 | 2022-08-03 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | LimF is a versatile prenyltransferase for histidine-C-geranylation on diverse non-natural substrates
Nat Catal, 2022
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7XNG
 | | Crystal structure of CBP bromodomain liganded with Y08092(31g) | | 分子名称: | 3-[(1-ethanoylindol-3-yl)carbonylamino]-5-[[(2S)-oxan-2-yl]oxymethyl]benzoic acid, CREB-binding protein, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Xiang, Q, Zhang, Y, Wang, C, Song, M, Xu, Y. | | 登録日 | 2022-04-28 | | 公開日 | 2022-06-01 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Crystal structure of CBP bromodomain liganded with Y08092(31g)
To Be Published
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7XM7
 | | Crystal Structure of the CBP in complex with the Y08188 | | 分子名称: | 1,2-ETHANEDIOL, 3-ethanoyl-~{N}-[2-fluoranyl-3-(1-methylpyrazol-4-yl)phenyl]-7-methoxy-indolizine-1-carboxamide, CREB-binding protein, ... | | 著者 | Xiang, Q, Zhang, Y, Wang, C, Song, M, Xu, Y. | | 登録日 | 2022-04-25 | | 公開日 | 2022-06-22 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | | 主引用文献 | Discovery and optimization of 1-(1H-indol-1-yl)ethanone derivatives as potent and selective CBP bromodomain inhibitors
To Be Published
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7VLB
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5Y1H
 | | Crystal structure of Plasmodium falciparum aminopeptidase N in complex with (S)-2-(3-(2,4-difluorobenzyl)ureido)-N-hydroxy-4-methylpentanamide | | 分子名称: | (2R)-2-[[2,4-bis(fluoranyl)phenyl]methylcarbamoylamino]-4-methyl-N-oxidanyl-pentanamide, GLYCEROL, M1 family aminopeptidase, ... | | 著者 | Marapaka, A.K, Zhang, Y, Addlagatta, A. | | 登録日 | 2017-07-20 | | 公開日 | 2018-08-01 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | Crystal structure of Plasmodium falciparum aminopeptidase N in complex with (S)-2-(3-(2,4-difluorobenzyl)ureido)-N-hydroxy-4-methylpentanamide
To Be Published
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5Y1R
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5Y3I
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5Y1S
 | | Crystal structure of Plasmodium falciparum aminopeptidase N in complex with (S)-2-(3-(3,4-dimethylbenzyl)ureido)-N-hydroxy-4-methylpentanamide | | 分子名称: | (2R)-2-[(3,4-dimethylphenyl)methylcarbamoylamino]-4-methyl-N-oxidanyl-pentanamide, (2S)-2-[(3,4-dimethylphenyl)methylcarbamoylamino]-4-methyl-N-oxidanyl-pentanamide, GLYCEROL, ... | | 著者 | Marapaka, A.K, Zhang, Y, Addlagatta, A. | | 登録日 | 2017-07-21 | | 公開日 | 2018-08-01 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | | 主引用文献 | Crystal structure of Plasmodium falciparum aminopeptidase N in complex with (S)-2-(3-(3,4-dimethylbenzyl)ureido)-N-hydroxy-4-methylpentanamide
To Be Published
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5Y1V
 | | Crystal structure of Plasmodium falciparum aminopeptidase N in complex with (S)-2-(3-(2,6-diethylphenyl)ureido)- N-hydroxy-4-methylpentanamide | | 分子名称: | (2R)-2-[(2,6-diethylphenyl)carbamoylamino]-4-methyl-N-oxidanyl-pentanamide, GLYCEROL, M1 family aminopeptidase, ... | | 著者 | Marapaka, A.K, Zhang, Y, Addlagatta, A. | | 登録日 | 2017-07-21 | | 公開日 | 2018-08-01 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | | 主引用文献 | Crystal structure of Plasmodium falciparum aminopeptidase N in complex with (S)-2-(3-(2,6-diethylphenyl)ureido)- N-hydroxy-4-methylpentanamide
To Be Published
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5Y19
 | | Crystal structure of Plasmodium falciparum aminopeptidase N in complex with (S)-2-((2S,3R)-3-amino-2-hydroxy-4-phenylbutanamido)- N-hydroxy-4-methylpentanamide. | | 分子名称: | (2S)-2-[[(2S,3R)-3-azanyl-2-oxidanyl-4-phenyl-butanoyl]amino]-4-methyl-N-oxidanyl-pentanamide, GLYCEROL, M1 family aminopeptidase, ... | | 著者 | Marapaka, A.K, Zhang, Y, Addlagatta, A. | | 登録日 | 2017-07-19 | | 公開日 | 2018-08-01 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Crystal structure of Plasmodium falciparum aminopeptidase N in complex with (S)-2-((2S,3R)-3-amino-2-hydroxy-4-phenylbutanamido)- N-hydroxy-4-methylpentanamide.
To Be Published
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7VCF
 | | Cryo-EM structure of Chlamydomonas TOC-TIC supercomplex | | 分子名称: | 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Wu, J, Yan, Z, Jin, Z, Zhang, Y. | | 登録日 | 2021-09-02 | | 公開日 | 2022-11-30 | | 最終更新日 | 2022-12-21 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | Structure of a TOC-TIC supercomplex spanning two chloroplast envelope membranes.
Cell, 185, 2022
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7CMU
 | | Dopamine Receptor D3R-Gi-Pramipexole complex | | 分子名称: | (6S)-N6-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Xu, P, Huang, S, Mao, C, Krumm, B, Zhou, X, Tan, Y, Huang, X.-P, Liu, Y, Shen, D.-D, Jiang, Y, Yu, X, Jiang, H, Melcher, K, Roth, B, Cheng, X, Zhang, Y, Xu, H. | | 登録日 | 2020-07-29 | | 公開日 | 2021-03-10 | | 最終更新日 | 2021-04-07 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structures of the human dopamine D3 receptor-G i complexes.
Mol.Cell, 81, 2021
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7CMV
 | | Dopamine Receptor D3R-Gi-PD128907 complex | | 分子名称: | (4aR,10bR)-4-propyl-3,4a,5,10b-tetrahydro-2H-chromeno[4,3-b][1,4]oxazin-9-ol, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Xu, P, Huang, S, Mao, C, Krumm, B, Zhou, X, Tan, Y, Huang, X.-P, Liu, Y, Shen, D.-D, Jiang, Y, Yu, X, Jiang, H, Melcher, K, Roth, B, Cheng, X, Zhang, Y, Xu, H. | | 登録日 | 2020-07-29 | | 公開日 | 2021-03-10 | | 最終更新日 | 2021-04-07 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Structures of the human dopamine D3 receptor-G i complexes.
Mol.Cell, 81, 2021
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7C72
 | | Structure of a mycobacterium tuberculosis puromycin-hydrolyzing peptidase | | 分子名称: | D-MALATE, GLYCEROL, Prolyl oligopeptidase | | 著者 | Ruiz-Carrillo, D, Zhao, Y.H, Feng, Q, Zhou, X, Zhang, Y, Jiang, J, Lukman, M. | | 登録日 | 2020-05-22 | | 公開日 | 2021-03-24 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.00004458 Å) | | 主引用文献 | Mycobacterium tuberculosis puromycin hydrolase displays a prolyl oligopeptidase fold and an acyl aminopeptidase activity.
Proteins, 89, 2021
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