7XM7
Crystal Structure of the CBP in complex with the Y08188
Summary for 7XM7
Entry DOI | 10.2210/pdb7xm7/pdb |
Descriptor | CREB-binding protein, 3-ethanoyl-~{N}-[2-fluoranyl-3-(1-methylpyrazol-4-yl)phenyl]-7-methoxy-indolizine-1-carboxamide, GLYCEROL, ... (8 entities in total) |
Functional Keywords | bromodomain, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 4 |
Total formula weight | 64902.50 |
Authors | |
Primary citation | Xiang, Q.,Zhang, Y.,Wang, C.,Song, M.,Xu, Y. Discovery and optimization of 1-(1H-indol-1-yl)ethanone derivatives as potent and selective CBP bromodomain inhibitors To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.36 Å) |
Structure validation
Download full validation report