7XM7
Crystal Structure of the CBP in complex with the Y08188
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | CREB-binding protein | polymer | 133 | 15891.3 | 4 | UniProt (Q92793) Pfam (PF00439) In PDB | Homo sapiens (human) | |
2 | A, B | 3-ethanoyl-~{N}-[2-fluoranyl-3-(1-methylpyrazol-4-yl)phenyl]-7-methoxy-indolizine-1-carboxamide | non-polymer | 406.4 | 2 | Chemie (GAY) | |||
3 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
4 | B, C | NITRATE ION | non-polymer | 62.0 | 2 | Chemie (NO3) | |||
5 | B | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
6 | C | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
7 | D | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
8 | water | water | 18.0 | 72 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1081 - 1197 (UniProt: Q92793)
PDB | External Database | Details |
---|---|---|
Met 1065 | - | expression tag |
Lys 1066 | - | expression tag |
Lys 1067 | - | expression tag |
Gly 1068 | - | expression tag |
His 1069 | - | expression tag |
His 1070 | - | expression tag |
His 1071 | - | expression tag |
His 1072 | - | expression tag |
His 1073 | - | expression tag |
His 1074 | - | expression tag |
Leu 1075 | - | expression tag |
Val 1076 | - | expression tag |
Pro 1077 | - | expression tag |
Arg 1078 | - | expression tag |
Gly 1079 | - | expression tag |
Ser 1080 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 63565.2 | |
Non-Polymers* | Number of molecules | 9 |
Total formula weight | 1337.3 | |
All* | Total formula weight | 64902.5 |