7CMU

Dopamine Receptor D3R-Gi-Pramipexole complex

Summary for 7CMU

• Entry DOI: 10.2210/pdb7cmu/pdb
• EMDB information: 30410
• Descriptor: Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total)
• Functional Keywords: g protein-coupled receptor, dopamine receptor, membrane protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 5
• Total formula weight: 173685.30

Authors

Xu, P.,Huang, S.,Mao, C.,Krumm, B.,Zhou, X.,Tan, Y.,Huang, X.-P.,Liu, Y.,Shen, D.-D.,Jiang, Y.,Yu, X.,Jiang, H.,Melcher, K.,Roth, B.,Cheng, X.,Zhang, Y.,Xu, H. (deposition date: 2020-07-29, release date: 2021-03-10, Last modification date: 2021-04-07)

• Primary citation: Xu, P.,Huang, S.,Mao, C.,Krumm, B.E.,Zhou, X.E.,Tan, Y.,Huang, X.P.,Liu, Y.,Shen, D.D.,Jiang, Y.,Yu, X.,Jiang, H.,Melcher, K.,Roth, B.L.,Cheng, X.,Zhang, Y.,Xu, H.E.; Structures of the human dopamine D3 receptor-G i complexes.; Mol.Cell, 81:1147-, 2021; PubMed: 33548201; DOI: 10.1016/j.molcel.2021.01.003

Experimental method

ELECTRON MICROSCOPY (3 Å)