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PDB: 744 件
9B43
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Mycolicibacterium smegmatis MmpL4 structure
分子名称: MmpL4 protein
著者Maharjan, R, Klenotic, P.A, Zhang, Z, Yu, E.W.
登録日2024-03-20
公開日2024-10-02
実験手法ELECTRON MICROSCOPY (2.95 Å)
主引用文献Mycolicibacterium smegmatis MmpL4 structure
To Be Published
8JHB
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FZD6 Gs complex
分子名称: Frizzled-6, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Xu, F, Zhang, Z.
登録日2023-05-23
公開日2024-01-17
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献A framework for Frizzled-G protein coupling and implications to the PCP signaling pathways.
Cell Discov, 10, 2024
8JHI
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FZD3-Gs complex
分子名称: Frizzled-3, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Xu, F, Zhang, Z.
登録日2023-05-23
公開日2024-01-17
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献A framework for Frizzled-G protein coupling and implications to the PCP signaling pathways.
Cell Discov, 10, 2024
8JH7
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FZD6 in inactive state
分子名称: Frizzled-6,Soluble cytochrome b562, anti-BRIL Fab Heavy chain, anti-BRIL Fab Light chain, ...
著者Xu, F, Zhang, Z.
登録日2023-05-22
公開日2024-01-17
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献A framework for Frizzled-G protein coupling and implications to the PCP signaling pathways.
Cell Discov, 10, 2024
8JHC
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FZD3 in inactive state
分子名称: Frizzled-3,Soluble cytochrome b562, anti-BRIL Fab Heavy chain, anti-BRIL Fab Light chain, ...
著者Xu, F, Zhang, Z.
登録日2023-05-23
公開日2024-01-17
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献A framework for Frizzled-G protein coupling and implications to the PCP signaling pathways.
Cell Discov, 10, 2024
3OMH
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Crystal structure of PTPN22 in complex with SKAP-HOM pTyr75 peptide
分子名称: Src kinase-associated phosphoprotein 2, Tyrosine-protein phosphatase non-receptor type 22
著者Yu, X, Sun, J.-P, Zhang, S, Zhang, Z.-Y.
登録日2010-08-26
公開日2011-06-29
最終更新日2011-09-14
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Substrate Specificity of Lymphoid-specific Tyrosine Phosphatase (Lyp) and Identification of Src Kinase-associated Protein of 55 kDa Homolog (SKAP-HOM) as a Lyp Substrate.
J.Biol.Chem., 286, 2011
8JIN
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The local refined map of XBB spike protein (S) in complex with bispecific antibody G7-Fc
分子名称: 7F3 Fv, GW01 Fv, Spike glycoprotein
著者Ma, Y, Mao, Q, Wang, Y, Zhang, Z.
登録日2023-05-27
公開日2024-05-29
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (2.45 Å)
主引用文献Structure of XBB spike protein (S) di-trimer in complex with bispecific antibody G7-Fc at 3.75 Angstroms resolution.
To Be Published
2MOX
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solution structure of tandem SH3 domain of Sorbin and SH3 domain-containing protein 1
分子名称: Sorbin and SH3 domain-containing protein 1
著者Zhao, D, Wang, C, Zhang, J, Wu, J, Shi, Y, Zhang, Z, Gong, Q.
登録日2014-05-07
公開日2014-05-28
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural investigation of the interaction between the tandem SH3 domains of c-Cbl-associated protein and vinculin
J.Struct.Biol., 187, 2014
4DGX
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LEOPARD Syndrome-Associated SHP2/Y279C mutant
分子名称: Tyrosine-protein phosphatase non-receptor type 11
著者Yu, Z.H, Xu, J, Walls, C.D, Chen, L, Zhang, S, Wu, L, Wang, L.N, Liu, S.J, Zhang, Z.Y.
登録日2012-01-27
公開日2013-03-06
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and Mechanistic Insights into LEOPARD Syndrome-Associated SHP2 Mutations.
J.Biol.Chem., 288, 2013
4UI9
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Atomic structure of the human Anaphase-Promoting Complex
分子名称: ANAPHASE-PROMOTING COMPLEX SUBUNIT 1, ANAPHASE-PROMOTING COMPLEX SUBUNIT 10, ANAPHASE-PROMOTING COMPLEX SUBUNIT 11, ...
著者Chang, L, Zhang, Z, Yang, J, McLaughlin, S.H, Barford, D.
登録日2015-03-27
公開日2015-06-17
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Atomic Structure of the Apc and its Mechanism of Protein Ubiquitination
Nature, 522, 2015
7Y1T
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Complex of integrin alphaV/beta8 and L-TGF-beta1 at a ratio of 1:2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Duan, Z, Zhang, Z.
登録日2022-06-08
公開日2022-08-31
最終更新日2022-09-07
実験手法ELECTRON MICROSCOPY (3.24 Å)
主引用文献Specificity of TGF-beta 1 signal designated by LRRC33 and integrin alpha V beta 8.
Nat Commun, 13, 2022
7Y1R
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Human L-TGF-beta1 in complex with the anchor protein LRRC33
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Duan, Z, Zhang, Z.
登録日2022-06-08
公開日2022-08-31
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (4.01 Å)
主引用文献Specificity of TGF-beta 1 signal designated by LRRC33 and integrin alpha V beta 8.
Nat Commun, 13, 2022
2FF0
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Solution Structure of Steroidogenic Factor 1 DNA Binding Domain Bound to its Target Sequence in the Inhibin alpha-subunit Promoter
分子名称: CTGTGGCCCTGAGCC, GGCTCAGGGCCACAG, Steroidogenic factor 1, ...
著者Little, T.H, Zhang, Y, Matulis, C.K, Weck, J, Zhang, Z, Ramachandran, A, Mayo, K.E, Radhakrishnan, I.
登録日2005-12-17
公開日2006-04-11
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Sequence-specific deoxyribonucleic Acid (DNA) recognition by steroidogenic factor 1: a helix at the carboxy terminus of the DNA binding domain is necessary for complex stability.
Mol.Endocrinol., 20, 2006
9AVG
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Structure of human calcium-sensing receptor in complex with chimeric Gs (miniGis) protein in nanodiscs
分子名称: (19R,22S,25R)-22,25,26-trihydroxy-16,22-dioxo-17,21,23-trioxa-22lambda~5~-phosphahexacosan-19-yl (9Z)-octadec-9-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zuo, H, Park, J, Frangaj, A, Ye, J, Lu, G, Manning, J.J, Asher, W.B, Lu, Z, Hu, G, Wang, L, Mendez, J, Eng, E, Zhang, Z, Lin, X, Grasucci, R, Hendrickson, W.A, Clarke, O.B, Javitch, J.A, Conigrave, A.D, Fan, Q.R.
登録日2024-03-02
公開日2024-04-17
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Promiscuous G-protein activation by the calcium-sensing receptor.
Nature, 629, 2024
9AXF
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Structure of human calcium-sensing receptor in complex with chimeric Gq (miniGisq) protein in detergent
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(2-chlorophenyl)-N-[(1R)-1-(3-methoxyphenyl)ethyl]propan-1-amine, ...
著者Zuo, H, Park, J, Frangaj, A, Ye, J, Lu, G, Manning, J.J, Asher, W.B, Lu, Z, Hu, G, Wang, L, Mendez, J, Eng, E, Zhang, Z, Lin, X, Grasucci, R, Hendrickson, W.A, Clarke, O.B, Javitch, J.A, Conigrave, A.D, Fan, Q.R.
登録日2024-03-06
公開日2024-04-17
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Promiscuous G-protein activation by the calcium-sensing receptor.
Nature, 629, 2024
9AVL
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Structure of human calcium-sensing receptor in complex with Gi3 protein in nanodiscs
分子名称: (19R,22S,25R)-22,25,26-trihydroxy-16,22-dioxo-17,21,23-trioxa-22lambda~5~-phosphahexacosan-19-yl (9Z)-octadec-9-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zuo, H, Park, J, Frangaj, A, Ye, J, Lu, G, Manning, J.J, Asher, W.B, Lu, Z, Hu, G, Wang, L, Mendez, J, Eng, E, Zhang, Z, Lin, X, Grasucci, R, Hendrickson, W.A, Clarke, O.B, Javitch, J.A, Conigrave, A.D, Fan, Q.R.
登録日2024-03-04
公開日2024-04-17
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Promiscuous G-protein activation by the calcium-sensing receptor.
Nature, 629, 2024
9AYF
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Structure of human calcium-sensing receptor in complex with Gi1 (miniGi1) protein in detergent
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(2-chlorophenyl)-N-[(1R)-1-(3-methoxyphenyl)ethyl]propan-1-amine, ...
著者Zuo, H, Park, J, Frangaj, A, Ye, J, Lu, G, Manning, J.J, Asher, W.B, Lu, Z, Hu, G, Wang, L, Mendez, J, Eng, E, Zhang, Z, Lin, X, Grasucci, R, Hendrickson, W.A, Clarke, O.B, Javitch, J.A, Conigrave, A.D, Fan, Q.R.
登録日2024-03-07
公開日2024-04-17
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Promiscuous G-protein activation by the calcium-sensing receptor.
Nature, 629, 2024
9ASB
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Structure of human calcium-sensing receptor in complex with chimeric Gq (miniGisq) protein in nanodiscs
分子名称: (19R,22S,25R)-22,25,26-trihydroxy-16,22-dioxo-17,21,23-trioxa-22lambda~5~-phosphahexacosan-19-yl (9Z)-octadec-9-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zuo, H, Park, J, Frangaj, A, Ye, J, Lu, G, Manning, J.J, Asher, W.B, Lu, Z, Hu, G, Wang, L, Mendez, J, Eng, E, Zhang, Z, Lin, X, Grasucci, R, Hendrickson, W.A, Clarke, O.B, Javitch, J.A, Conigrave, A.D, Fan, Q.R.
登録日2024-02-24
公開日2024-04-17
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Promiscuous G-protein activation by the calcium-sensing receptor.
Nature, 629, 2024
1SG0
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Crystal structure analysis of QR2 in complex with resveratrol
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, NRH dehydrogenase [quinone] 2, RESVERATROL, ...
著者Buryanovskyy, L, Fu, Y, Boyd, M, Ma, Y, Tsieh, T.C, Wu, J.M, Zhang, Z.
登録日2004-02-22
公開日2005-01-25
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of quinone reductase 2 in complex with resveratrol
Biochemistry, 43, 2004
4BH6
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Insights into degron recognition by APC coactivators from the structure of an Acm1-Cdh1 complex
分子名称: APC/C ACTIVATOR PROTEIN CDH1, APC/C-CDH1 MODULATOR 1
著者He, J, Chao, W.C.H, Zhang, Z, Yang, J, Cronin, N, Barford, D.
登録日2013-03-29
公開日2013-06-05
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Insights Into Degron Recognition by Apc/C Coactivators from the Structure of an Acm1-Cdh1 Complex.
Mol.Cell, 50, 2013
5G04
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Structure of the human APC-Cdc20-Hsl1 complex
分子名称: ANAPHASE-PROMOTING COMPLEX SUBUNIT 1, ANAPHASE-PROMOTING COMPLEX SUBUNIT 10, ANAPHASE-PROMOTING COMPLEX SUBUNIT 11, ...
著者Zhang, S, Chang, L, Alfieri, C, Zhang, Z, Yang, J, Maslen, S, Skehel, M, Barford, D.
登録日2016-03-16
公開日2016-05-25
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Molecular Mechanism of Apc/C Activation by Mitotic Phosphorylation.
Nature, 533, 2016
7YE6
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BAM-EspP complex structure with BamA-N427C/EspP-R1297C mutations in nanodisc
分子名称: Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, Outer membrane protein assembly factor BamC, ...
著者Shen, C, Chang, S, Luo, Q, Zhang, Z, Luo, B, Lu, G, Zhu, X, Wei, X, Dong, C, Zhang, X, Tang, X, Dong, H.
登録日2022-07-05
公開日2023-07-12
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis of BAM-mediated outer membrane beta-barrel protein assembly.
Nature, 617, 2023
7YE4
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BAM-EspP complex structure with BamA-G431C and G781C/EspP-N1293C and A1043C mutations in nanodisc
分子名称: Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, Outer membrane protein assembly factor BamC, ...
著者Shen, C, Chang, S, Luo, Q, Zhang, Z, Luo, B, Lu, G, Zhu, X, Wei, X, Dong, C, Zhang, X, Tang, X, Dong, H.
登録日2022-07-05
公開日2023-07-12
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis of BAM-mediated outer membrane beta-barrel protein assembly.
Nature, 617, 2023
8JMX
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The crystal structure of human aurka kinase domain in complex with AURKA-A2
分子名称: 5-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2-oxidanyl-benzaldehyde, Aurora kinase A
著者Zhu, C.J, Zhang, Z.M.
登録日2023-06-05
公開日2023-10-18
実験手法X-RAY DIFFRACTION (2.95020175 Å)
主引用文献Multitarget inhibitors/probes that target LRRK2 and AURORA A kinases noncovalently and covalently.
Chem.Commun.(Camb.), 59, 2023
1RXD
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Crystal structure of human protein tyrosine phosphatase 4A1
分子名称: protein tyrosine phosphatase type IVA, member 1; Protein tyrosine phosphatase IVA1
著者Sun, J.P, Fedorov, A.A, Almo, S.C, Zhang, Z.Y, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2003-12-18
公開日2004-12-28
最終更新日2021-02-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural genomics of protein phosphatases.
J.STRUCT.FUNCT.GENOM., 8, 2007

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