2FF0

Solution Structure of Steroidogenic Factor 1 DNA Binding Domain Bound to its Target Sequence in the Inhibin alpha-subunit Promoter

Summary for 2FF0

• Entry DOI: 10.2210/pdb2ff0/pdb
• Descriptor: GGCTCAGGGCCACAG, CTGTGGCCCTGAGCC, Steroidogenic factor 1, ... (4 entities in total)
• Functional Keywords: nuclear hormone receptor, protein-dna complex, monomeric receptor-dna complex, hormone-growth factor-dna complex, hormone/growth factor/dna
• Biological source: Mus musculus (house mouse); More
• Cellular location: Nucleus: P33242
• Total number of polymer chains: 3
• Total formula weight: 21203.72

Authors

Little, T.H.,Zhang, Y.,Matulis, C.K.,Weck, J.,Zhang, Z.,Ramachandran, A.,Mayo, K.E.,Radhakrishnan, I. (deposition date: 2005-12-17, release date: 2006-04-11, Last modification date: 2024-05-29)

• Primary citation: Little, T.H.,Zhang, Y.,Matulis, C.K.,Weck, J.,Zhang, Z.,Ramachandran, A.,Mayo, K.E.,Radhakrishnan, I.; Sequence-specific deoxyribonucleic Acid (DNA) recognition by steroidogenic factor 1: a helix at the carboxy terminus of the DNA binding domain is necessary for complex stability.; Mol.Endocrinol., 20:831-843, 2006; PubMed: 16339274; DOI: 10.1210/me.2005-0384

Experimental method

SOLUTION NMR