7WHN
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7WHP
| Pentameric turret of Bombyx mori cytoplasmic polyhedrosis virus after spike detaches. | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, S-ADENOSYLMETHIONINE, Structural protein VP3 | 著者 | Zhang, Y, Cui, Y, Sun, J, Zhou, Z.H. | 登録日 | 2021-12-31 | 公開日 | 2022-02-02 | 最終更新日 | 2022-02-16 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Multiple conformations of trimeric spikes visualized on a non-enveloped virus. Nat Commun, 13, 2022
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7WF9
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7WF8
| Crystal structure of mouse SNX25 RGS domain in space group P212121 | 分子名称: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | 著者 | Zhang, Y, Xu, J, Liu, J. | 登録日 | 2021-12-26 | 公開日 | 2022-10-26 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Structural Studies Reveal Unique Non-canonical Regulators of G Protein Signaling Homology (RH) Domains in Sorting Nexins. J.Mol.Biol., 434, 2022
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7D6E
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7D6D
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7E7S
| WT transporter state1 | 分子名称: | CALCIUM ION, Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | 著者 | Zhang, Y, Watanabe, S, Tsutsumi, A, Inaba, K. | 登録日 | 2021-02-27 | 公開日 | 2021-09-08 | 最終更新日 | 2022-02-23 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Cryo-EM analysis provides new mechanistic insight into ATP binding to Ca 2+ -ATPase SERCA2b. Embo J., 40, 2021
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7XH3
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7XFV
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4URT
| The crystal structure of a fragment of netrin-1 in complex with FN5- FN6 of DCC | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ... | 著者 | Finci, L.I, Krueger, N, Sun, X, Zhang, J, Chegkazi, M, Wu, Y, Schenk, G, Mertens, H.D.T, Svergun, D.I, Zhang, Y, Wang, J.-h, Meijers, R. | 登録日 | 2014-07-02 | 公開日 | 2014-09-10 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | The Crystal Structure of Netrin-1 in Complex with Dcc Reveals the Bi-Functionality of Netrin-1 as a Guidance Cue Neuron, 83, 2014
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6PWW
| Cryo-EM structure of MLL1 in complex with RbBP5 and WDR5 bound to the nucleosome | 分子名称: | DNA (146-MER), Histone H2A type 1, Histone H2B 1.1, ... | 著者 | Park, S.H, Ayoub, A, Lee, Y.T, Xu, J, Zhang, W, Zhang, B, Zhang, Y, Cianfrocco, M.A, Su, M, Dou, Y, Cho, U. | 登録日 | 2019-07-23 | 公開日 | 2019-12-18 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Cryo-EM structure of the human MLL1 core complex bound to the nucleosome. Nat Commun, 10, 2019
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2V0G
| LEUCYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS COMPLEXED WITH A tRNA(leu) transcript with 5-FLUORO-1,3-DIHYDRO-1-HYDROXY-2,1- BENZOXABOROLE (AN2690) forming an adduct to the ribose of adenosine- 76 in the enzyme editing site. | 分子名称: | AMINOACYL-TRNA SYNTHETASE, LEUCINE, MERCURY (II) ION, ... | 著者 | Rock, F, Mao, W, Yaremchuk, A, Tukalo, M, Crepin, T, Zhou, H, Zhang, Y, Hernandez, V, Akama, T, Baker, S, Plattner, J, Shapiro, L, Martinis, S.A, Benkovic, S.J, Cusack, S, Alley, M.R.K. | 登録日 | 2007-05-14 | 公開日 | 2007-07-03 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | An Antifungal Agent Inhibits an Aminoacyl-tRNA Synthetase by Trapping tRNA in the Editing Site. Science, 316, 2007
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1SPI
| CRYSTAL STRUCTURE OF SPINACH CHLOROPLAST FRUCTOSE-1,6-BISPHOSPHATASE AT 2.8 ANGSTROMS RESOLUTION | 分子名称: | FRUCTOSE 1,6-BISPHOSPHATASE | 著者 | Villeret, V, Huang, S, Zhang, Y, Xue, Y, Lipscomb, W.N. | 登録日 | 1994-12-14 | 公開日 | 1995-02-27 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal structure of spinach chloroplast fructose-1,6-bisphosphatase at 2.8 A resolution. Biochemistry, 34, 1995
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6PWX
| Cryo-EM structure of RbBP5 bound to the nucleosome | 分子名称: | DNA (146-MER), Histone H2A type 1, Histone H2B 1.1, ... | 著者 | Park, S.H, Ayoub, A, Lee, Y.T, Xu, J, Zhang, W, Zhang, B, Zhang, Y, Cianfrocco, M.A, Su, M, Dou, Y, Cho, U. | 登録日 | 2019-07-23 | 公開日 | 2019-12-18 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Cryo-EM structure of the human MLL1 core complex bound to the nucleosome. Nat Commun, 10, 2019
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6PWV
| Cryo-EM structure of MLL1 core complex bound to the nucleosome | 分子名称: | DNA (147-MER), Histone H2A type 1, Histone H2B 1.1, ... | 著者 | Park, S.H, Ayoub, A, Lee, Y.T, Xu, J, Zhang, W, Zhang, B, Zhang, Y, Cianfrocco, M.A, Su, M, Dou, Y, Cho, U. | 登録日 | 2019-07-23 | 公開日 | 2019-12-18 | 最終更新日 | 2023-08-16 | 実験手法 | ELECTRON MICROSCOPY (6.2 Å) | 主引用文献 | Cryo-EM structure of the human MLL1 core complex bound to the nucleosome. Nat Commun, 10, 2019
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2HKO
| Crystal structure of LSD1 | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Lysine-specific histone demethylase 1 | 著者 | Chen, Y, Yang, Y.T, Wang, F, Yanane, K, Zhang, Y, Lei, M. | 登録日 | 2006-07-05 | 公開日 | 2006-08-29 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal structure of human histone lysine-specific demethylase 1 (LSD1). Proc.Natl.Acad.Sci.Usa, 103, 2006
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6VUA
| X-ray structure of human CD38 catalytic domain with 2'-Cl-araNAD+ | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, DI(HYDROXYETHYL)ETHER, ... | 著者 | Dai, Z, Zhang, X.N, Nasertorabi, F, Han, G.W, Stevens, R.C, Zhang, Y. | 登録日 | 2020-02-14 | 公開日 | 2020-06-03 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Synthesis of site-specific antibody-drug conjugates by ADP-ribosyl cyclases. Sci Adv, 6, 2020
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5Y8Y
| Crystal Structure Analysis of the BRD4 | 分子名称: | 1,2-ETHANEDIOL, 5-bromanyl-2-methoxy-N-(6-methoxy-3-methyl-1,2-benzoxazol-5-yl)benzenesulfonamide, Bromodomain-containing protein 4, ... | 著者 | Xu, Y, Zhang, Y, Song, M, Wang, C. | 登録日 | 2017-08-21 | 公開日 | 2018-06-13 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | Structure-Based Discovery and Optimization of Benzo[ d]isoxazole Derivatives as Potent and Selective BET Inhibitors for Potential Treatment of Castration-Resistant Prostate Cancer (CRPC) J. Med. Chem., 61, 2018
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6PB1
| Cryo-EM structure of Urocortin 1-bound Corticotropin-releasing factor 2 receptor in complex with Gs protein and Nb35 | 分子名称: | CHOLESTEROL, Corticotropin-releasing factor receptor 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Ma, S, Shen, Q, Zhao, L.-H, Mao, C, Zhou, X.E, Shen, D.-D, de Waal, P.W, Bi, P, Li, C, Jiang, Y, Wang, M.-W, Sexton, P.M, Wootten, D, Melcher, K, Zhang, Y, Xu, H.E. | 登録日 | 2019-06-12 | 公開日 | 2020-02-12 | 最終更新日 | 2020-02-19 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Molecular Basis for Hormone Recognition and Activation of Corticotropin-Releasing Factor Receptors. Mol.Cell, 77, 2020
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5Y93
| Crystal Structure Analysis of the BRD4 | 分子名称: | 1,2-ETHANEDIOL, 2-[[5-[(5-bromanyl-2-methoxy-phenyl)sulfonylamino]-3-methyl-1,2-benzoxazol-6-yl]oxy]-N-(2-morpholin-4-ylethyl)ethanamide, Bromodomain-containing protein 4, ... | 著者 | Xu, Y, Zhang, Y, Song, M, Wang, C. | 登録日 | 2017-08-22 | 公開日 | 2018-06-13 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | Structure-Based Discovery and Optimization of Benzo[ d]isoxazole Derivatives as Potent and Selective BET Inhibitors for Potential Treatment of Castration-Resistant Prostate Cancer (CRPC) J. Med. Chem., 61, 2018
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5BZ0
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5Y8W
| Crystal Structure Analysis of the BRD4 | 分子名称: | 1,2-ETHANEDIOL, 5-bromanyl-2-methoxy-N-(3-methyl-6-oxidanyl-1,2-benzoxazol-5-yl)benzenesulfonamide, Bromodomain-containing protein 4, ... | 著者 | Xu, Y, Zhang, Y, Song, M, Wang, C. | 登録日 | 2017-08-21 | 公開日 | 2018-06-13 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Structure-Based Discovery and Optimization of Benzo[ d]isoxazole Derivatives as Potent and Selective BET Inhibitors for Potential Treatment of Castration-Resistant Prostate Cancer (CRPC) J. Med. Chem., 61, 2018
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5Y94
| Crystal Structure Analysis of the BRD4 | 分子名称: | 5-bromanyl-2-methoxy-N-[3-methyl-6-(methylamino)-1,2-benzoxazol-5-yl]benzenesulfonamide, Bromodomain-containing protein 4, GLYCEROL, ... | 著者 | Xu, Y, Zhang, Y, Song, M, Wang, C. | 登録日 | 2017-08-22 | 公開日 | 2018-06-13 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure-Based Discovery and Optimization of Benzo[ d]isoxazole Derivatives as Potent and Selective BET Inhibitors for Potential Treatment of Castration-Resistant Prostate Cancer (CRPC) J. Med. Chem., 61, 2018
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5YQX
| Crystal Structure Analysis of the BRD4 | 分子名称: | (2R)-2-(cyclopropylmethyl)-7-(3,5-dimethyl-1,2-oxazol-4-yl)-4H-1,4-benzoxazin-3-one, 1,2-ETHANEDIOL, Bromodomain-containing protein 4, ... | 著者 | Xue, X, Zhang, Y, Wang, C, Song, M. | 登録日 | 2017-11-08 | 公開日 | 2018-11-28 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Benzoxazinone-containing 3,5-dimethylisoxazole derivatives as BET bromodomain inhibitors for treatment of castration-resistant prostate cancer. Eur.J.Med.Chem., 152, 2018
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5Y8Z
| Crystal Structure Analysis of the BRD4 | 分子名称: | 1,2-ETHANEDIOL, 5-bromanyl-N-(3,6-dimethyl-1,2-benzoxazol-5-yl)-2-methoxy-benzenesulfonamide, Bromodomain-containing protein 4, ... | 著者 | Xu, Y, Zhang, Y, Song, M, Wang, C. | 登録日 | 2017-08-22 | 公開日 | 2018-06-13 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | Structure-Based Discovery and Optimization of Benzo[ d]isoxazole Derivatives as Potent and Selective BET Inhibitors for Potential Treatment of Castration-Resistant Prostate Cancer (CRPC) J. Med. Chem., 61, 2018
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