7X7T
| Cryo-EM structure of SARS-CoV-2 spike protein in complex with three nAbs X01, X10 and X17 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, X01 heavy chain, ... | 著者 | Sun, H, Liu, L, Zheng, Q, Li, S, Zhang, T, Xia, N. | 登録日 | 2022-03-10 | 公開日 | 2022-08-17 | 最終更新日 | 2022-11-23 | 実験手法 | ELECTRON MICROSCOPY (3.48 Å) | 主引用文献 | The neutralizing breadth of antibodies targeting diverse conserved epitopes between SARS-CoV and SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 119, 2022
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7X7V
| Cryo-EM structure of SARS-CoV spike protein in complex with three nAbs X01, X10 and X17 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, X01 heavy chain, ... | 著者 | Sun, H, Liu, L, Zhang, T, Zheng, Q, Li, S, Xia, N. | 登録日 | 2022-03-10 | 公開日 | 2022-08-17 | 最終更新日 | 2022-11-23 | 実験手法 | ELECTRON MICROSCOPY (3.83 Å) | 主引用文献 | The neutralizing breadth of antibodies targeting diverse conserved epitopes between SARS-CoV and SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 119, 2022
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7X7U
| Cryo-EM structure of SARS-CoV-2 Delta variant spike protein in complex with three nAbs X01, X10 and X17 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, X01 heavy chain, ... | 著者 | Sun, H, Liu, L, Zhang, T, Zheng, Q, Li, S, Xia, N. | 登録日 | 2022-03-10 | 公開日 | 2022-08-17 | 最終更新日 | 2022-11-23 | 実験手法 | ELECTRON MICROSCOPY (3.77 Å) | 主引用文献 | The neutralizing breadth of antibodies targeting diverse conserved epitopes between SARS-CoV and SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 119, 2022
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5C3O
| Crystal structure of the C-terminal truncated Neurospora crassa T7H (NcT7HdeltaC) in apo form | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Thymine dioxygenase | 著者 | Li, W, Zhang, T, Ding, J. | 登録日 | 2015-06-17 | 公開日 | 2015-10-21 | 最終更新日 | 2015-12-02 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Molecular basis for the substrate specificity and catalytic mechanism of thymine-7-hydroxylase in fungi Nucleic Acids Res., 43, 2015
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5C77
| A novel protein arginine methyltransferase | 分子名称: | Protein arginine N-methyltransferase SFM1, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Lv, F, Zhang, T, Ding, J. | 登録日 | 2015-06-24 | 公開日 | 2016-01-13 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis for Sfm1 functioning as a protein arginine methyltransferase. Cell Discov, 1, 2015
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5XYN
| The crystal structure of Csm2-Psy3-Shu1-Shu2 complex from budding yeast | 分子名称: | Chromosome segregation in meiosis protein 2, Platinum sensitivity protein 3, Suppressor of HU sensitivity involved in recombination protein 1, ... | 著者 | Zhang, S, Zhang, T, Ding, J. | 登録日 | 2017-07-09 | 公開日 | 2017-11-08 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structural basis for the functional role of the Shu complex in homologous recombination. Nucleic Acids Res., 45, 2017
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8IR0
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8IQX
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3OV6
| CD1c in complex with MPM (mannosyl-beta1-phosphomycoketide) | 分子名称: | 1-O-[(S)-hydroxy{[(4S,8S,16S,20S)-4,8,12,16,20-pentamethylheptacosyl]oxy}phosphoryl]-beta-D-mannopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ... | 著者 | Scharf, L, Li, N.S, Hawk, A.J, Garzon, D, Zhang, T, Kazen, A.R, Shah, S, Haddadian, E.J, Saghatelian, A, Faraldo-Gomez, J.D, Meredith, S.C, Piccirilli, J.A, Adams, E.J. | 登録日 | 2010-09-15 | 公開日 | 2011-01-19 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.502 Å) | 主引用文献 | The 2.5 A structure of CD1c in complex with a mycobacterial lipid reveals an open groove ideally suited for diverse antigen presentation Immunity, 33, 2010
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4LRV
| Crystal structure of DndE from Escherichia coli B7A involved in DNA phosphorothioation modification | 分子名称: | DNA sulfur modification protein DndE | 著者 | Hu, W, Wang, C.K, Liang, J.D, Zhang, T.L, Yang, M, Hu, Z.P, Wang, Z.J, Lan, W.X, Wu, H.M, Ding, J.P, Wu, G, Deng, Z.X, Cao, C. | 登録日 | 2013-07-21 | 公開日 | 2013-08-28 | 最終更新日 | 2024-10-30 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural insights into DndE from Escherichia coli B7A involved in DNA phosphorothioation modification Cell Res., 22, 2012
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5WQA
| Crystal structure of PDE4D catalytic domain complexed with Selaginpulvilins K | 分子名称: | 1-[2-(4-hydroxyphenyl)ethynyl]-9,9-bis(4-methoxyphenyl)-7-oxidanyl-fluorene-2-carbaldehyde, MAGNESIUM ION, ZINC ION, ... | 著者 | Huang, Y, Zhang, T, Zheng, X, Yin, S, Luo, H.B. | 登録日 | 2016-11-24 | 公開日 | 2017-02-22 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The discovery, complex crystal structure, and recognition mechanism of a novel natural PDE4 inhibitor from Selaginella pulvinata Biochem. Pharmacol., 130, 2017
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6BNB
| Crystal structure of DDB1-CRBN-BRD4(BD1) complex bound to dBET57 PROTAC | 分子名称: | Bromodomain-containing protein 4, DNA damage-binding protein 1, Protein cereblon, ... | 著者 | Nowak, R.P, DeAngelo, S.L, Buckley, D, Ishoey, M, He, Z, Zhang, T, Bradner, J.E, Fischer, E.S. | 登録日 | 2017-11-16 | 公開日 | 2018-05-30 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (6.343 Å) | 主引用文献 | Plasticity in binding confers selectivity in ligand-induced protein degradation. Nat. Chem. Biol., 14, 2018
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7BTA
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7BTC
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7BTD
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5Y6M
| Zika virus helicase in complex with ADP-AlF3 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Helicase domain from Genome polyprotein, ... | 著者 | Yang, X.Y, Chen, C, Tian, H.L, Chi, H, Mu, Z.Y, Zhang, T.Q, Yang, K.L, Zhao, Q, Liu, X.H, Wang, Z.F, Ji, X.Y, Yang, H.T. | 登録日 | 2017-08-12 | 公開日 | 2018-07-04 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.002 Å) | 主引用文献 | Mechanism of ATP hydrolysis by the Zika virus helicase. FASEB J., 32, 2018
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3RIB
| Human lysine methyltransferase Smyd2 in complex with AdoHcy | 分子名称: | N-lysine methyltransferase SMYD2, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ... | 著者 | Xu, S, Zhang, T, Zhong, C, Ding, J. | 登録日 | 2011-04-13 | 公開日 | 2011-07-20 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | 主引用文献 | Structure of human lysine methyltransferase Smyd2 reveals insights into the substrate divergence in Smyd proteins J Mol Cell Biol, 3, 2011
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5Y6N
| Zika virus helicase in complex with ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Helicase domain from Genome polyprotein, MANGANESE (II) ION | 著者 | Yang, X.Y, Chen, C, Tian, H.L, Chi, H, Mu, Z.Y, Zhang, T.Q, Yang, K.L, Zhao, Q, Liu, X.H, Wang, Z.F, Ji, X.Y, Yang, H.T. | 登録日 | 2017-08-12 | 公開日 | 2018-07-04 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.571 Å) | 主引用文献 | Mechanism of ATP hydrolysis by the Zika virus helicase. FASEB J., 32, 2018
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4M6W
| Crystal structure of the C-terminal segment of FANCM in complex with FAAP24 | 分子名称: | Fanconi anemia group M protein, Fanconi anemia-associated protein of 24 kDa, SULFATE ION | 著者 | Yang, H, Zhang, T, Tong, L, Ding, J. | 登録日 | 2013-08-11 | 公開日 | 2013-10-02 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural insights into the functions of the FANCM-FAAP24 complex in DNA repair. Nucleic Acids Res., 41, 2013
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4LTU
| Crystal Structure of Ferredoxin from Rhodopseudomonas palustris HaA2 | 分子名称: | FE2/S2 (INORGANIC) CLUSTER, Ferredoxin | 著者 | Zhou, W.H, Zhang, T, Yang, H, Bell, S.G, Wong, L.-L. | 登録日 | 2013-07-24 | 公開日 | 2014-10-15 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | Crystal Structure of Ferredoxin from Rhodopseudomonas palustris HaA2 To be Published
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6KEA
| crystal structure of MBP-tagged REV7-IpaB complex | 分子名称: | Maltose-binding periplasmic protein,LINKER,hREV7,LINKER,Invasin IpaB,hREV3 | 著者 | Wang, X, Pernicone, N, Pertz, L, Hua, D.P, Zhang, T.Q, Listovsky, T, Xie, W. | 登録日 | 2019-07-04 | 公開日 | 2019-09-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | REV7 has a dynamic adaptor region to accommodate small GTPase RAN/ShigellaIpaB ligands, and its activity is regulated by the RanGTP/GDP switch. J.Biol.Chem., 294, 2019
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4FBG
| Crystal structure of Treponema denticola trans-2-enoyl-CoA reductase in complex with NAD | 分子名称: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Putative reductase TDE_0597 | 著者 | Hu, K, Zhao, M, Zhang, T, Yang, S, Ding, J. | 登録日 | 2012-05-23 | 公開日 | 2012-11-28 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (3.02 Å) | 主引用文献 | Structures of trans-2-enoyl-CoA reductases from Clostridium acetobutylicum and Treponema denticola: insights into the substrate specificity and the catalytic mechanism Biochem.J., 449, 2013
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3RPN
| Crystal structure of human kappa class glutathione transferase in complex with S-hexylglutathione | 分子名称: | Glutathione S-transferase kappa 1, S-HEXYLGLUTATHIONE | 著者 | Wang, B, Peng, Y, Zhang, T, Ding, J. | 登録日 | 2011-04-27 | 公開日 | 2011-07-13 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structures and kinetic studies of human Kappa class glutathione transferase provide insights into the catalytic mechanism. Biochem.J., 439, 2011
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3RPP
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6V97
| Kindlin-3 double deletion mutant short form | 分子名称: | Fermitin family homolog 3 | 著者 | Xu, Z, Zhang, T.L, Xu, Z, Sun, J.J, Ding, J.P, Ma, Y.Q. | 登録日 | 2019-12-13 | 公開日 | 2020-07-22 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.381 Å) | 主引用文献 | Structure basis of the FERM domain of kindlin-3 in supporting integrin alpha IIb beta 3 activation in platelets. Blood Adv, 4, 2020
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